(-)-Epigallocatechin is a lipid of Polyketides (PK) class. The involved functions are known as Protective Agents, inhibitors, Process, Drug Kinetics and Fermentation. (-)-epigallocatechin often locates in Hepatic, Blood, Membrane, Back and apical membrane. The associated genes with (-)-Epigallocatechin are ADRBK1 gene and FASTK Gene. The related lipids are 1,2-dilinolenoyl-3-(4-aminobutyryl)propane-1,2,3-triol. The related experimental models are Rodent Model and Transgenic Model.
To understand associated biological information of (-)-Epigallocatechin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
There are no associated biomedical information in the current reference collection.
We collected disease MeSH terms mapped to the references associated with (-)-Epigallocatechin
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Glioblastoma | D005909 | 27 associated lipids |
| Liver Diseases | D008107 | 31 associated lipids |
| Mammary Neoplasms, Experimental | D008325 | 67 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
| Hemolysis | D006461 | 131 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
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| Function | Cross reference | Weighted score | Related literatures |
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| Lipid concept | Cross reference | Weighted score | Related literatures |
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| Gene | Cross reference | Weighted score | Related literatures |
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Rodent Model are used in the study 'Dietary (-)-epicatechin as a potent inhibitor of βγ-secretase amyloid precursor protein processing.' (Cox CJ et al., 2015) and Rodent Model are used in the study 'Effects of dosing condition on the oral bioavailability of green tea catechins after single-dose administration of Polyphenon E in healthy individuals.' (Chow HH et al., 2005).
Transgenic Model are used in the study 'Dietary (-)-epicatechin as a potent inhibitor of βγ-secretase amyloid precursor protein processing.' (Cox CJ et al., 2015).
| Model | Cross reference | Weighted score | Related literatures |
|---|
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Ko CH et al. | Pro-bone and antifat effects of green tea and its polyphenol, epigallocatechin, in rat mesenchymal stem cells in vitro. | 2011 | J. Agric. Food Chem. | pmid:21877759 |
| Li Y et al. | Epigenetic regulation of caloric restriction in aging. | 2011 | BMC Med | pmid:21867551 |
| Katiyar SK and Raman C | Green tea: a new option for the prevention or control of osteoarthritis. | 2011 | Arthritis Res. Ther. | pmid:21861859 |
| Chuu CP et al. | Androgens as therapy for androgen receptor-positive castration-resistant prostate cancer. | 2011 | J. Biomed. Sci. | pmid:21859492 |
| Fujimura Y et al. | Metabolomics-driven nutraceutical evaluation of diverse green tea cultivars. | 2011 | PLoS ONE | pmid:21853132 |
| Stingl JC et al. | Protocol for minimizing the risk of metachronous adenomas of the colorectum with green tea extract (MIRACLE): a randomised controlled trial of green tea extract versus placebo for nutriprevention of metachronous colon adenomas in the elderly population. | 2011 | BMC Cancer | pmid:21851602 |
| Ciesek S et al. | The green tea polyphenol, epigallocatechin-3-gallate, inhibits hepatitis C virus entry. | 2011 | Hepatology | pmid:21837753 |
| Chawla R et al. | Himalayan Bioresource Rhodiola imbricata as a promising radioprotector for nuclear and radiological emergencies. | 2010 | J Pharm Bioallied Sci | pmid:21829317 |
| Obara K et al. | Mechanism of potentiation by tea epigallocatechin of contraction in porcine coronary artery: the role of protein kinase Cδ-mediated CPI-17 phosphorylation. | 2011 | Eur. J. Pharmacol. | pmid:21827748 |
| Wu X et al. | Analysis of binding interaction between (-)-epigallocatechin (EGC) and β-lactoglobulin by multi-spectroscopic method. | 2011 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:21820944 |
| Abib RT et al. | Epigallocatechin-3-gallate protects rat brain mitochondria against cadmium-induced damage. | 2011 | Food Chem. Toxicol. | pmid:21798304 |
| Gibellini L et al. | Quercetin and cancer chemoprevention. | 2011 | Evid Based Complement Alternat Med | pmid:21792362 |
| Wisuitiprot W et al. | In vitro human skin permeation and cutaneous metabolism of catechins from green tea extract and green tea extract-loaded chitosan microparticles. | 2011 | Int J Cosmet Sci | pmid:21790662 |
| Tibe O et al. | Condensed tannins and flavonoids from the forage legume sulla (Hedysarum coronarium). | 2011 | J. Agric. Food Chem. | pmid:21780793 |
| Ueda M et al. | Tea catechins modulate the glucose transport system in 3T3-L1 adipocytes. | 2010 | Food Funct | pmid:21776468 |
| Babich H et al. | Research strategies in the study of the pro-oxidant nature of polyphenol nutraceuticals. | 2011 | J Toxicol | pmid:21776260 |
| Kaur T et al. | Short interfering RNA against STAT1 attenuates cisplatin-induced ototoxicity in the rat by suppressing inflammation. | 2011 | Cell Death Dis | pmid:21776018 |
| Kudva P et al. | Effect of green tea catechin, a local drug delivery system as an adjunct to scaling and root planing in chronic periodontitis patients: A clinicomicrobiological study. | 2011 | J Indian Soc Periodontol | pmid:21772720 |
| Venkateswara B et al. | Green tea extract for periodontal health. | 2011 | J Indian Soc Periodontol | pmid:21772716 |
| Brown AL et al. | Health effects of green tea catechins in overweight and obese men: a randomised controlled cross-over trial. | 2011 | Br. J. Nutr. | pmid:21736785 |