(-)-Epigallocatechin is a lipid of Polyketides (PK) class. The involved functions are known as Protective Agents, inhibitors, Process, Drug Kinetics and Fermentation. (-)-epigallocatechin often locates in Hepatic, Blood, Membrane, Back and apical membrane. The associated genes with (-)-Epigallocatechin are ADRBK1 gene and FASTK Gene. The related lipids are 1,2-dilinolenoyl-3-(4-aminobutyryl)propane-1,2,3-triol. The related experimental models are Rodent Model and Transgenic Model.
To understand associated biological information of (-)-Epigallocatechin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
There are no associated biomedical information in the current reference collection.
We collected disease MeSH terms mapped to the references associated with (-)-Epigallocatechin
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Glioblastoma | D005909 | 27 associated lipids |
| Liver Diseases | D008107 | 31 associated lipids |
| Mammary Neoplasms, Experimental | D008325 | 67 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
| Hemolysis | D006461 | 131 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
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| Function | Cross reference | Weighted score | Related literatures |
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| Lipid concept | Cross reference | Weighted score | Related literatures |
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| Gene | Cross reference | Weighted score | Related literatures |
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Rodent Model are used in the study 'Dietary (-)-epicatechin as a potent inhibitor of βγ-secretase amyloid precursor protein processing.' (Cox CJ et al., 2015) and Rodent Model are used in the study 'Effects of dosing condition on the oral bioavailability of green tea catechins after single-dose administration of Polyphenon E in healthy individuals.' (Chow HH et al., 2005).
Transgenic Model are used in the study 'Dietary (-)-epicatechin as a potent inhibitor of βγ-secretase amyloid precursor protein processing.' (Cox CJ et al., 2015).
| Model | Cross reference | Weighted score | Related literatures |
|---|
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Chung JH et al. | Green tea formulations with vitamin C and xylitol on enhanced intestinal transport of green tea catechins. | 2013 | J. Food Sci. | pmid:23551173 |
| Wang Z et al. | Bioactivity-guided identification and cell signaling technology to delineate the lactate dehydrogenase A inhibition effects of Spatholobus suberectus on breast cancer. | 2013 | PLoS ONE | pmid:23457597 |
| Cryan LM et al. | 1,2,3,4,6-Penta-O-galloyl-β-D-glucopyranose inhibits angiogenesis via inhibition of capillary morphogenesis gene 2. | 2013 | J. Med. Chem. | pmid:23394144 |
| Lin G et al. | Enantioselective total syntheses of (+)-gallocatechin, (-)-epigallocatechin, and 8-C-ascorbyl-(-)-epigallocatechin. | 2013 | Chem Asian J | pmid:23362126 |
| Park JS et al. | EGCG inhibits recepteur d'origine nantais expression by suppressing Egr-1 in gastric cancer cells. | 2013 | Int. J. Oncol. | pmid:23337910 |
| Bai LP et al. | Aminoglycosylation can enhance the G-quadruplex binding activity of epigallocatechin. | 2013 | PLoS ONE | pmid:23335983 |
| Hong YH et al. | Enzymatic improvement in the polyphenol extractability and antioxidant activity of green tea extracts. | 2013 | Biosci. Biotechnol. Biochem. | pmid:23291774 |
| Koga K et al. | Proanthocyanidin oligomers isolated from Salacia reticulata leaves potently inhibit pancreatic lipase activity. | 2013 | J. Food Sci. | pmid:23278351 |
| Ghosh S et al. | (-)-Epicatechin gallate prevents alkali-salt mediated fibrillogenesis of hen egg white lysozyme. | 2013 | Int. J. Biol. Macromol. | pmid:23219698 |
| Kamihira-Ishijima M et al. | Inhibitory mechanism of pancreatic amyloid fibril formation: formation of the complex between tea catechins and the fragment of residues 22-27. | 2012 | Biochemistry | pmid:23205879 |
| Roy S et al. | Combination therapy of dexamethasone with epigallocatechin enhances tibiotarsal bone articulation and modulates oxidative status correlates with cartilage cytokines expression in the early phase of experimental arthritis. | 2013 | Eur. J. Pharmacol. | pmid:23183110 |
| Bindon KA and Smith PA | Comparison of the affinity and selectivity of insoluble fibres and commercial proteins for wine proanthocyanidins. | 2013 | Food Chem | pmid:23122145 |
| Thakur D et al. | Antimicrobial activities of tocklai vegetative tea clones. | 2011 | Indian J. Microbiol. | pmid:23024406 |
| Bandaruk Y et al. | Evaluation of the inhibitory effects of quercetin-related flavonoids and tea catechins on the monoamine oxidase-A reaction in mouse brain mitochondria. | 2012 | J. Agric. Food Chem. | pmid:23009399 |
| Unno T et al. | Gallated form of tea catechin, not nongallated form, increases fecal starch excretion in rats. | 2012 | J. Nutr. Sci. Vitaminol. | pmid:23007066 |
| Skrt M et al. | Interactions of different polyphenols with bovine serum albumin using fluorescence quenching and molecular docking. | 2012 | Food Chem | pmid:22980822 |
| Ikeda H et al. | Incompatibility between propericiazine oral solution and tea-based drink. | 2012 | Chem. Pharm. Bull. | pmid:22976331 |
| Colon M and Nerin C | Role of catechins in the antioxidant capacity of an active film containing green tea, green coffee, and grapefruit extracts. | 2012 | J. Agric. Food Chem. | pmid:22973940 |
| Trabelsi N et al. | Isolation of powerful antioxidants from the medicinal halophyte Limoniastrum guyonianum. | 2012 | Food Chem | pmid:22953875 |
| Arimboor R and Arumughan C | Effect of polymerization on antioxidant and xanthine oxidase inhibitory potential of sea buckthorn (H. rhamnoides) proanthocyanidins. | 2012 | J. Food Sci. | pmid:22938149 |