(-)-Epigallocatechin is a lipid of Polyketides (PK) class. The involved functions are known as Protective Agents, inhibitors, Process, Drug Kinetics and Fermentation. (-)-epigallocatechin often locates in Hepatic, Blood, Membrane, Back and apical membrane. The associated genes with (-)-Epigallocatechin are ADRBK1 gene and FASTK Gene. The related lipids are 1,2-dilinolenoyl-3-(4-aminobutyryl)propane-1,2,3-triol. The related experimental models are Rodent Model and Transgenic Model.
To understand associated biological information of (-)-Epigallocatechin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
There are no associated biomedical information in the current reference collection.
We collected disease MeSH terms mapped to the references associated with (-)-Epigallocatechin
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Glioblastoma | D005909 | 27 associated lipids |
| Liver Diseases | D008107 | 31 associated lipids |
| Mammary Neoplasms, Experimental | D008325 | 67 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
| Hemolysis | D006461 | 131 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
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| Function | Cross reference | Weighted score | Related literatures |
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| Lipid concept | Cross reference | Weighted score | Related literatures |
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| Gene | Cross reference | Weighted score | Related literatures |
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Rodent Model are used in the study 'Dietary (-)-epicatechin as a potent inhibitor of βγ-secretase amyloid precursor protein processing.' (Cox CJ et al., 2015) and Rodent Model are used in the study 'Effects of dosing condition on the oral bioavailability of green tea catechins after single-dose administration of Polyphenon E in healthy individuals.' (Chow HH et al., 2005).
Transgenic Model are used in the study 'Dietary (-)-epicatechin as a potent inhibitor of βγ-secretase amyloid precursor protein processing.' (Cox CJ et al., 2015).
| Model | Cross reference | Weighted score | Related literatures |
|---|
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Ikeda H et al. | [Mechanism of interaction between risperidone and tea catechin (2) influence of presence of galloyl group in catechin on insoluble complex formation with risperidone]. | 2012 | Yakugaku Zasshi | pmid:22214589 |
| Sasaki T et al. | Green tea catechins increase the force of contraction in isolated guinea pig atrial muscle preparations by increasing the amplitude of intracellular Ca2+ concentration. | 2012 | J. Vet. Med. Sci. | pmid:22864409 |
| Mak JC | Potential role of green tea catechins in various disease therapies: progress and promise. | 2012 | Clin. Exp. Pharmacol. Physiol. | pmid:22229384 |
| Long LH and Halliwell B | The effects of oxaloacetate on hydrogen peroxide generation from ascorbate and epigallocatechin gallate in cell culture media: potential for altering cell metabolism. | 2012 | Biochem. Biophys. Res. Commun. | pmid:22166196 |
| Ghiringhelli F et al. | Immunomodulation and anti-inflammatory roles of polyphenols as anticancer agents. | 2012 | Anticancer Agents Med Chem | pmid:22292769 |
| Maeda-Yamamoto M et al. | Epicatechin-3-O-(3″-O-methyl)-gallate content in various tea cultivars (Camellia sinensis L.) and its in vitro inhibitory effect on histamine release. | 2012 | J. Agric. Food Chem. | pmid:22339247 |
| Samanidou V et al. | Simultaneous determination of polyphenols and major purine alkaloids in Greek Sideritis species, herbal extracts, green tea, black tea, and coffee by high-performance liquid chromatography-diode array detection. | 2012 | J Sep Sci | pmid:22282422 |
| Narotzki B et al. | Green tea: a promising natural product in oral health. | 2012 | Arch. Oral Biol. | pmid:22226360 |
| Iovanna J et al. | Current knowledge on pancreatic cancer. | 2012 | Front Oncol | pmid:22655256 |
| de-Faria FM et al. | Antioxidant action of mangrove polyphenols against gastric damage induced by absolute ethanol and ischemia-reperfusion in the rat. | 2012 | ScientificWorldJournal | pmid:22654592 |
| Park CH et al. | Protective Effects of Corni Fructus against Advanced Glycation Endproducts and Radical Scavenging. | 2012 | Evid Based Complement Alternat Med | pmid:22649473 |
| Umar KM et al. | Engineering the production of major catechins by Escherichia coli carrying metabolite genes of Camellia sinensis. | 2012 | ScientificWorldJournal | pmid:22645428 |
| Jimenez-Del-Rio M and Velez-Pardo C | The bad, the good, and the ugly about oxidative stress. | 2012 | Oxid Med Cell Longev | pmid:22619696 |
| Zhang X et al. | Characterisation of anthocyanidin reductase from Shuchazao green tea. | 2012 | J. Sci. Food Agric. | pmid:22173936 |
| Margina D et al. | Quercetin and epigallocatechin gallate induce in vitro a dose-dependent stiffening and hyperpolarizing effect on the cell membrane of human mononuclear blood cells. | 2012 | Int J Mol Sci | pmid:22606013 |
| Koppula S et al. | Reactive oxygen species and inhibitors of inflammatory enzymes, NADPH oxidase, and iNOS in experimental models of Parkinson's disease. | 2012 | Mediators Inflamm. | pmid:22577256 |
| Nickerson NK et al. | Decreased autocrine EGFR signaling in metastatic breast cancer cells inhibits tumor growth in bone and mammary fat pad. | 2012 | PLoS ONE | pmid:22276166 |
| Cohen SD et al. | Impact of diurnal temperature variation on grape berry development, proanthocyanidin accumulation, and the expression of flavonoid pathway genes. | 2012 | J. Exp. Bot. | pmid:22268158 |
| Wen KC et al. | Ixora parviflora Protects against UVB-Induced Photoaging by Inhibiting the Expression of MMPs, MAP Kinases, and COX-2 and by Promoting Type I Procollagen Synthesis. | 2012 | Evid Based Complement Alternat Med | pmid:22203872 |
| Rathore K et al. | Green tea catechin intervention of reactive oxygen species-mediated ERK pathway activation and chronically induced breast cell carcinogenesis. | 2012 | Carcinogenesis | pmid:22045026 |