(-)-Epigallocatechin is a lipid of Polyketides (PK) class. The involved functions are known as Protective Agents, inhibitors, Process, Drug Kinetics and Fermentation. (-)-epigallocatechin often locates in Hepatic, Blood, Membrane, Back and apical membrane. The associated genes with (-)-Epigallocatechin are ADRBK1 gene and FASTK Gene. The related lipids are 1,2-dilinolenoyl-3-(4-aminobutyryl)propane-1,2,3-triol. The related experimental models are Rodent Model and Transgenic Model.
To understand associated biological information of (-)-Epigallocatechin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
There are no associated biomedical information in the current reference collection.
We collected disease MeSH terms mapped to the references associated with (-)-Epigallocatechin
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Body Weight | D001835 | 333 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Hemolysis | D006461 | 131 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
| Mammary Neoplasms, Experimental | D008325 | 67 associated lipids |
| Liver Diseases | D008107 | 31 associated lipids |
| Glioblastoma | D005909 | 27 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
| Gene | Cross reference | Weighted score | Related literatures |
|---|
Rodent Model are used in the study 'Dietary (-)-epicatechin as a potent inhibitor of βγ-secretase amyloid precursor protein processing.' (Cox CJ et al., 2015) and Rodent Model are used in the study 'Effects of dosing condition on the oral bioavailability of green tea catechins after single-dose administration of Polyphenon E in healthy individuals.' (Chow HH et al., 2005).
Transgenic Model are used in the study 'Dietary (-)-epicatechin as a potent inhibitor of βγ-secretase amyloid precursor protein processing.' (Cox CJ et al., 2015).
| Model | Cross reference | Weighted score | Related literatures |
|---|
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Li C and Choi JS | Effects of epigallocatechin gallate on the bioavailability and pharmacokinetics of diltiazem in rats. | 2008 | Pharmazie | pmid:19069242 |
| Chan EW et al. | Antioxidant and antibacterial properties of green, black, and herbal teas of Camellia sinensis. | 2011 | Pharmacognosy Res | pmid:22224051 |
| Sánchez JC et al. | 1,1-Diphenyl-2-picrylhydrazyl radical and superoxide anion scavenging activity of Rhizophora mangle (L.) bark. | 2010 | Pharmacognosy Res | pmid:21589751 |
| Saraf S and Kaur CD | Phytoconstituents as photoprotective novel cosmetic formulations. | 2010 | Pharmacogn Rev | pmid:22228936 |
| Chahar MK et al. | Flavonoids: A versatile source of anticancer drugs. | 2011 | Pharmacogn Rev | pmid:22096313 |
| Ahmed F and Urooj A | Anticholinesterase activities of cold and hot aqueous extracts of F. racemosa stem bark. | 2010 | Pharmacogn Mag | pmid:20668582 |
| Momtaz S et al. | Investigation of the possible biological activities of a poisonous South African plant; Hyaenanche globosa (Euphorbiaceae). | 2010 | Pharmacogn Mag | pmid:20548934 |
| Yeh CW et al. | Suppression of fatty acid synthase in MCF-7 breast cancer cells by tea and tea polyphenols: a possible mechanism for their hypolipidemic effects. | 2003 | Pharmacogenomics J. | pmid:12931129 |
| Yoshino S et al. | Effect of emulsification on the skin permeation and UV protection of catechin. | 2014 | Pharm Dev Technol | pmid:23639253 |
| Qa'dan F et al. | Proanthocyanidins from Ginkgo biloba leaf extract and their radical scavenging activity. | 2011 | Pharm Biol | pmid:21388236 |