(-)-Epigallocatechin

(-)-Epigallocatechin is a lipid of Polyketides (PK) class. The involved functions are known as Protective Agents, inhibitors, Process, Drug Kinetics and Fermentation. (-)-epigallocatechin often locates in Hepatic, Blood, Membrane, Back and apical membrane. The associated genes with (-)-Epigallocatechin are ADRBK1 gene and FASTK Gene. The related lipids are 1,2-dilinolenoyl-3-(4-aminobutyryl)propane-1,2,3-triol. The related experimental models are Rodent Model and Transgenic Model.

Cross Reference

Introduction

To understand associated biological information of (-)-Epigallocatechin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with (-)-Epigallocatechin?

There are no associated biomedical information in the current reference collection.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with (-)-Epigallocatechin

MeSH term MeSH ID Detail
Body Weight D001835 333 associated lipids
Lung Neoplasms D008175 171 associated lipids
Adenocarcinoma D000230 166 associated lipids
Hemolysis D006461 131 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Liver Diseases D008107 31 associated lipids
Glioblastoma D005909 27 associated lipids
Total 8

PubChem Associated disorders and diseases

What pathways are associated with (-)-Epigallocatechin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with (-)-Epigallocatechin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with (-)-Epigallocatechin?


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What lipids are associated with (-)-Epigallocatechin?

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What genes are associated with (-)-Epigallocatechin?

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Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with (-)-Epigallocatechin?

Rodent Model

Rodent Model are used in the study 'Dietary (-)-epicatechin as a potent inhibitor of βγ-secretase amyloid precursor protein processing.' (Cox CJ et al., 2015) and Rodent Model are used in the study 'Effects of dosing condition on the oral bioavailability of green tea catechins after single-dose administration of Polyphenon E in healthy individuals.' (Chow HH et al., 2005).

Transgenic Model

Transgenic Model are used in the study 'Dietary (-)-epicatechin as a potent inhibitor of βγ-secretase amyloid precursor protein processing.' (Cox CJ et al., 2015).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with (-)-Epigallocatechin

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Authors Title Published Journal PubMed Link
Qaâdan F et al. Polyphenols from Ginkgo biloba. 2010 Oct-Dec Sci Pharm pmid:21179324
Kang H et al. Green tea consumption and stomach cancer risk: a meta-analysis. 2010 Epidemiol Health pmid:21191454
Wagner AE et al. Ascorbic acid partly antagonizes resveratrol mediated heme oxygenase-1 but not paraoxonase-1 induction in cultured hepatocytes - role of the redox-regulated transcription factor Nrf2. 2011 BMC Complement Altern Med pmid:21199573
Maeda-Yamamoto M et al. Effect of green tea powder (Camellia sinensis L. cv. Benifuuki) particle size on O-methylated EGCG absorption in rats; The Kakegawa Study. 2011 Cytotechnology pmid:21207145
Ali MB et al. Berry skin development in Norton grape: distinct patterns of transcriptional regulation and flavonoid biosynthesis. 2011 BMC Plant Biol. pmid:21219654
Ishii T et al. Human serum albumin as an antioxidant in the oxidation of (-)-epigallocatechin gallate: participation of reversible covalent binding for interaction and stabilization. 2011 Biosci. Biotechnol. Biochem. pmid:21228463
Monobe M et al. Increased plasma concentration of epigallocatechin in mice after orally administering a green tea (Camellia sinensis L.) extract supplemented by steamed rice. 2011 Biosci. Biotechnol. Biochem. pmid:21228465
Minoda K et al. Influence of the galloyl moiety in tea catechins on binding affinity for human serum albumin. 2010 J. Nutr. Sci. Vitaminol. pmid:21228505
Mounsey RB and Teismann P Mitochondrial dysfunction in Parkinson's disease: pathogenesis and neuroprotection. 2010 Parkinsons Dis pmid:21234411
Javed T et al. In-vitro antiviral activity of Solanum nigrum against Hepatitis C Virus. 2011 Virol. J. pmid:21247464
Narukawa M et al. Evaluation of the bitterness of green tea catechins by a cell-based assay with the human bitter taste receptor hTAS2R39. 2011 Biochem. Biophys. Res. Commun. pmid:21272567
Sanna V et al. Targeted biocompatible nanoparticles for the delivery of (-)-epigallocatechin 3-gallate to prostate cancer cells. 2011 J. Med. Chem. pmid:21306166
Mukai K et al. Kinetic study of the quenching reaction of singlet oxygen by Pyrroloquinolinequinol (PQQH(2), a reduced form of Pyrroloquinolinequinone) in micellar solution. 2011 J. Agric. Food Chem. pmid:21309575
Wolf A et al. Targeting metabolic remodeling in glioblastoma multiforme. 2010 Oncotarget pmid:21317451
Vu HA et al. Green tea epigallocatechin gallate exhibits anticancer effect in human pancreatic carcinoma cells via the inhibition of both focal adhesion kinase and insulin-like growth factor-I receptor. 2010 J. Biomed. Biotechnol. pmid:21318151
Yang H et al. Characterization of unusual proanthocyanidins in leaves of bayberry ( Myrica rubra Sieb. et Zucc.). 2011 J. Agric. Food Chem. pmid:21319804
Wisuitiprot W et al. A novel technique for chitosan microparticle preparation using a water/silicone emulsion: green tea model. 2011 Int J Cosmet Sci pmid:21323933
Ziaedini A et al. Extraction of antioxidants and caffeine from green tea (Camelia sinensis) leaves: kinetics and modeling. 2010 Food Sci Technol Int pmid:21339166
Mazzio EA et al. The biochemical and cellular basis for nutraceutical strategies to attenuate neurodegeneration in Parkinson's disease. 2011 Int J Mol Sci pmid:21340000
Lv L et al. Genistein inhibits advanced glycation end product formation by trapping methylglyoxal. 2011 Chem. Res. Toxicol. pmid:21344933
Khalifé S and Zafarullah M Molecular targets of natural health products in arthritis. 2011 Arthritis Res. Ther. pmid:21345249
Pękal A et al. Evaluation of the antioxidant properties of fruit and flavoured black teas. 2011 Eur J Nutr pmid:21360165
Kylli P et al. Lingonberry (Vaccinium vitis-idaea) and European cranberry (Vaccinium microcarpon) proanthocyanidins: isolation, identification, and bioactivities. 2011 J. Agric. Food Chem. pmid:21370878
Lee YS et al. Inhibitory effect of glucodistylin from the bark of Quercus acutissima on human recombinant aldose reductase and sorbitol accumulation. 2011 Arch. Pharm. Res. pmid:21380803
Qa'dan F et al. Proanthocyanidins from Ginkgo biloba leaf extract and their radical scavenging activity. 2011 Pharm Biol pmid:21388236
Ras RT et al. Tea consumption enhances endothelial-dependent vasodilation; a meta-analysis. 2011 PLoS ONE pmid:21394199
Gavrilova V et al. Separation, characterization and quantification of phenolic compounds in blueberries and red and black currants by HPLC-DAD-ESI-MSn. 2011 J. Agric. Food Chem. pmid:21401099
Terra X et al. Procyanidin dimer B1 and trimer C1 impair inflammatory response signalling in human monocytes. 2011 Free Radic. Res. pmid:21405989
Cudmore MJ et al. Loss of Akt activity increases circulating soluble endoglin release in preeclampsia: identification of inter-dependency between Akt-1 and heme oxygenase-1. 2012 Eur. Heart J. pmid:21411816
Tachibana H Green tea polyphenol sensing. 2011 Proc. Jpn. Acad., Ser. B, Phys. Biol. Sci. pmid:21422740
Kim Y et al. The impact of packaging materials on the antioxidant phytochemical stability of aqueous infusions of green tea (Camellia sinensis) and yaupon holly (Ilex vomitoria) during cold storage. 2011 J. Agric. Food Chem. pmid:21434687
Tucci SA et al. The role of lipid and carbohydrate digestive enzyme inhibitors in the management of obesity: a review of current and emerging therapeutic agents. 2010 Diabetes Metab Syndr Obes pmid:21437083
Chandrasekara N and Shahidi F Effect of roasting on phenolic content and antioxidant activities of whole cashew nuts, kernels, and testa. 2011 J. Agric. Food Chem. pmid:21438525
Miller RJ et al. A preliminary investigation of the impact of catechol-O-methyltransferase genotype on the absorption and metabolism of green tea catechins. 2012 Eur J Nutr pmid:21445620
Riccio P et al. May diet and dietary supplements improve the wellness of multiple sclerosis patients? A molecular approach. 2011 Autoimmune Dis pmid:21461338
Sithranga Boopathy N and Kathiresan K Anticancer drugs from marine flora: an overview. 2010 J Oncol pmid:21461373
Park BJ et al. In vitro antifungal activity of epigallocatechin 3-O-gallate against clinical isolates of dermatophytes. 2011 Yonsei Med. J. pmid:21488200
Kim JA et al. New monoterpene glycosides and phenolic compounds from Distylium racemosum and their inhibitory activity against ribonuclease H. 2011 Bioorg. Med. Chem. Lett. pmid:21489793
Matsuda H et al. Structural requirements of flavonoids for the adipogenesis of 3T3-L1 cells. 2011 Bioorg. Med. Chem. pmid:21493073
Hu Y et al. Bioactive components from the tea polyphenols influence on endogenous antioxidant defense system and modulate inflammatory cytokines after total-body irradiation in mice. 2011 Phytomedicine pmid:21498061
Karth A et al. A case report of atrial fibrillation potentially induced by hydroxycut: a multicomponent dietary weight loss supplement devoid of sympathomimetic amines. 2010 J Pharm Pract pmid:21507821
Rajavelu A et al. The inhibition of the mammalian DNA methyltransferase 3a (Dnmt3a) by dietary black tea and coffee polyphenols. 2011 BMC Biochem. pmid:21510884
Chen Y et al. Effect of girdling at various positions of 'Huang Zhi Xiang' tea tree (Camellia sinensis) on the contents of catechins and starch in fresh leaf. 2011 Plant Foods Hum Nutr pmid:21523413
Erdogan S et al. Pressurized liquid extraction of phenolic compounds from Anatolia propolis and their radical scavenging capacities. 2011 Food Chem. Toxicol. pmid:21530603
Sivam AS et al. Properties of bread dough with added fiber polysaccharides and phenolic antioxidants: a review. 2010 J. Food Sci. pmid:21535512
de Jesus Reis Rosa L et al. The inhibitory effect of Camellia sinensis extracts against the neuromuscular blockade of Crotalus durissus terrificus venom. 2010 J Venom Res pmid:21544176
Sánchez JC et al. 1,1-Diphenyl-2-picrylhydrazyl radical and superoxide anion scavenging activity of Rhizophora mangle (L.) bark. 2010 Pharmacognosy Res pmid:21589751
Wei IH et al. (-)-Epigallocatechin gallate attenuates NADPH-d/nNOS expression in motor neurons of rats following peripheral nerve injury. 2011 BMC Neurosci pmid:21627848
Ankolekar C et al. Inhibitory potential of tea polyphenolics and influence of extraction time against Helicobacter pylori and lack of inhibition of beneficial lactic acid bacteria. 2011 J Med Food pmid:21663484
Zhao H et al. Changes of constituents and activity to apoptosis and cell cycle during fermentation of tea. 2011 Int J Mol Sci pmid:21673927
Yoo S et al. Antimicrobial traits of tea- and cranberry-derived polyphenols against Streptococcus mutans. 2011 Caries Res. pmid:21720161
Knott L et al. Regulation of osteoarthritis by omega-3 (n-3) polyunsaturated fatty acids in a naturally occurring model of disease. 2011 Osteoarthr. Cartil. pmid:21723952
Li S et al. Epigallocatechin gallate inhibits the HIV reverse transcription step. 2011 Antivir. Chem. Chemother. pmid:21730371
Brown AL et al. Health effects of green tea catechins in overweight and obese men: a randomised controlled cross-over trial. 2011 Br. J. Nutr. pmid:21736785
Venkateswara B et al. Green tea extract for periodontal health. 2011 J Indian Soc Periodontol pmid:21772716
Kudva P et al. Effect of green tea catechin, a local drug delivery system as an adjunct to scaling and root planing in chronic periodontitis patients: A clinicomicrobiological study. 2011 J Indian Soc Periodontol pmid:21772720
Kaur T et al. Short interfering RNA against STAT1 attenuates cisplatin-induced ototoxicity in the rat by suppressing inflammation. 2011 Cell Death Dis pmid:21776018
Babich H et al. Research strategies in the study of the pro-oxidant nature of polyphenol nutraceuticals. 2011 J Toxicol pmid:21776260
Ueda M et al. Tea catechins modulate the glucose transport system in 3T3-L1 adipocytes. 2010 Food Funct pmid:21776468
Tibe O et al. Condensed tannins and flavonoids from the forage legume sulla (Hedysarum coronarium). 2011 J. Agric. Food Chem. pmid:21780793
Wisuitiprot W et al. In vitro human skin permeation and cutaneous metabolism of catechins from green tea extract and green tea extract-loaded chitosan microparticles. 2011 Int J Cosmet Sci pmid:21790662
Gibellini L et al. Quercetin and cancer chemoprevention. 2011 Evid Based Complement Alternat Med pmid:21792362
Abib RT et al. Epigallocatechin-3-gallate protects rat brain mitochondria against cadmium-induced damage. 2011 Food Chem. Toxicol. pmid:21798304
Wu X et al. Analysis of binding interaction between (-)-epigallocatechin (EGC) and β-lactoglobulin by multi-spectroscopic method. 2011 Spectrochim Acta A Mol Biomol Spectrosc pmid:21820944
Obara K et al. Mechanism of potentiation by tea epigallocatechin of contraction in porcine coronary artery: the role of protein kinase Cδ-mediated CPI-17 phosphorylation. 2011 Eur. J. Pharmacol. pmid:21827748
Chawla R et al. Himalayan Bioresource Rhodiola imbricata as a promising radioprotector for nuclear and radiological emergencies. 2010 J Pharm Bioallied Sci pmid:21829317
Ciesek S et al. The green tea polyphenol, epigallocatechin-3-gallate, inhibits hepatitis C virus entry. 2011 Hepatology pmid:21837753
Stingl JC et al. Protocol for minimizing the risk of metachronous adenomas of the colorectum with green tea extract (MIRACLE): a randomised controlled trial of green tea extract versus placebo for nutriprevention of metachronous colon adenomas in the elderly population. 2011 BMC Cancer pmid:21851602
Fujimura Y et al. Metabolomics-driven nutraceutical evaluation of diverse green tea cultivars. 2011 PLoS ONE pmid:21853132
Chuu CP et al. Androgens as therapy for androgen receptor-positive castration-resistant prostate cancer. 2011 J. Biomed. Sci. pmid:21859492
Katiyar SK and Raman C Green tea: a new option for the prevention or control of osteoarthritis. 2011 Arthritis Res. Ther. pmid:21861859
Li Y et al. Epigenetic regulation of caloric restriction in aging. 2011 BMC Med pmid:21867551
Ko CH et al. Pro-bone and antifat effects of green tea and its polyphenol, epigallocatechin, in rat mesenchymal stem cells in vitro. 2011 J. Agric. Food Chem. pmid:21877759
Ingólfsson HI et al. Effects of green tea catechins on gramicidin channel function and inferred changes in bilayer properties. 2011 FEBS Lett. pmid:21896274
Lee JE et al. Metabolic dependence of green tea on plucking positions revisited: a metabolomic study. 2011 J. Agric. Food Chem. pmid:21899366
Salem MM et al. In vitro anti-uveal melanoma activity of phenolic compounds from the Egyptian medicinal plant Acacia nilotica. 2011 Fitoterapia pmid:21903153
Rahman S et al. In vitro antioxidant and anticancer activity of young Zingiber officinale against human breast carcinoma cell lines. 2011 BMC Complement Altern Med pmid:21933433
Tanaka T et al. Pathobiology and chemoprevention of bladder cancer. 2011 J Oncol pmid:21941546
Rodríguez-Durán LV et al. Novel strategies for upstream and downstream processing of tannin acyl hydrolase. 2011 Enzyme Res pmid:21941633
Derdemezis CS et al. Effect of Plant Polyphenols on Adipokine Secretion from Human SGBS Adipocytes. 2011 Biochem Res Int pmid:21949907
Zheng R et al. A comparative reverse docking strategy to identify potential antineoplastic targets of tea functional components and binding mode. 2011 Int J Mol Sci pmid:21954353
Atawodi SE Nigerian foodstuffs with prostate cancer chemopreventive polyphenols. 2011 Infect. Agents Cancer pmid:21992488
Arola-Arnal A and Bladé C Proanthocyanidins modulate microRNA expression in human HepG2 cells. 2011 PLoS ONE pmid:21998738
Chen CH et al. An in vitro hyperbaric oxygen system for evaluation of free radical damage and protection by catechins on hemorheological parameters. 2011 Clin. Hemorheol. Microcirc. pmid:22012826
Singh T and Katiyar SK Green tea catechins reduce invasive potential of human melanoma cells by targeting COX-2, PGE2 receptors and epithelial-to-mesenchymal transition. 2011 PLoS ONE pmid:22022384
Herges K et al. Neuroprotective effect of combination therapy of glatiramer acetate and epigallocatechin-3-gallate in neuroinflammation. 2011 PLoS ONE pmid:22022398
Song LL et al. β-carotene radical cation addition to green tea polyphenols. Mechanism of antioxidant antagonism in peroxidizing liposomes. 2011 J. Agric. Food Chem. pmid:22023371
Xu SF et al. Characterization of a highly polymeric proanthocyanidin fraction from persimmon pulp with strong Chinese cobra PLA2 inhibition effects. 2012 Fitoterapia pmid:22037569
Rathore K et al. Green tea catechin intervention of reactive oxygen species-mediated ERK pathway activation and chronically induced breast cell carcinogenesis. 2012 Carcinogenesis pmid:22045026
Kelsey N et al. Neuroprotective effects of anthocyanins on apoptosis induced by mitochondrial oxidative stress. 2011 Nutr Neurosci pmid:22053756
Horáková L Flavonoids in prevention of diseases with respect to modulation of Ca-pump function. 2011 Interdiscip Toxicol pmid:22058652
Petraglia AL et al. Stuck at the bench: Potential natural neuroprotective compounds for concussion. 2011 Surg Neurol Int pmid:22059141
Russo M et al. Phytochemicals in cancer prevention and therapy: truth or dare? 2010 Toxins (Basel) pmid:22069598
Nabekura T Overcoming multidrug resistance in human cancer cells by natural compounds. 2010 Toxins (Basel) pmid:22069634
Feucht W et al. Nuclei of Tsuga canadensis: role of flavanols in chromatin organization. 2011 Int J Mol Sci pmid:22072922
Lee UL and Choi SW The chemopreventive properties and therapeutic modulation of green tea polyphenols in oral squamous cell carcinoma. 2011 ISRN Oncol pmid:22084729
Hanlin RL et al. Detailed characterization of proanthocyanidins in skin, seeds, and wine of Shiraz and Cabernet Sauvignon wine grapes (Vitis vinifera). 2011 J. Agric. Food Chem. pmid:22085086
Chahar MK et al. Flavonoids: A versatile source of anticancer drugs. 2011 Pharmacogn Rev pmid:22096313
Wang Y et al. Simultaneous determination of seven bioactive components in Oolong tea Camellia sinensis: quality control by chemical composition and HPLC fingerprints. 2012 J. Agric. Food Chem. pmid:22098505
Calland N et al. (-)-Epigallocatechin-3-gallate is a new inhibitor of hepatitis C virus entry. 2012 Hepatology pmid:22105803