(-)-Epigallocatechin is a lipid of Polyketides (PK) class. The involved functions are known as Protective Agents, inhibitors, Process, Drug Kinetics and Fermentation. (-)-epigallocatechin often locates in Hepatic, Blood, Membrane, Back and apical membrane. The associated genes with (-)-Epigallocatechin are ADRBK1 gene and FASTK Gene. The related lipids are 1,2-dilinolenoyl-3-(4-aminobutyryl)propane-1,2,3-triol. The related experimental models are Rodent Model and Transgenic Model.
To understand associated biological information of (-)-Epigallocatechin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
There are no associated biomedical information in the current reference collection.
We collected disease MeSH terms mapped to the references associated with (-)-Epigallocatechin
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Body Weight | D001835 | 333 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Hemolysis | D006461 | 131 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
| Mammary Neoplasms, Experimental | D008325 | 67 associated lipids |
| Liver Diseases | D008107 | 31 associated lipids |
| Glioblastoma | D005909 | 27 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
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| Function | Cross reference | Weighted score | Related literatures |
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| Lipid concept | Cross reference | Weighted score | Related literatures |
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| Gene | Cross reference | Weighted score | Related literatures |
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Rodent Model are used in the study 'Dietary (-)-epicatechin as a potent inhibitor of βγ-secretase amyloid precursor protein processing.' (Cox CJ et al., 2015) and Rodent Model are used in the study 'Effects of dosing condition on the oral bioavailability of green tea catechins after single-dose administration of Polyphenon E in healthy individuals.' (Chow HH et al., 2005).
Transgenic Model are used in the study 'Dietary (-)-epicatechin as a potent inhibitor of βγ-secretase amyloid precursor protein processing.' (Cox CJ et al., 2015).
| Model | Cross reference | Weighted score | Related literatures |
|---|
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
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| Matsumoto Y et al. | Antibacterial and antifungal activities of new acylated derivatives of epigallocatechin gallate. | 2012 | Front Microbiol | pmid:22355295 |
| Egert S et al. | Simultaneous ingestion of dietary proteins reduces the bioavailability of galloylated catechins from green tea in humans. | 2013 | Eur J Nutr | pmid:22366739 |
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| Wang H et al. | Profiles and α-amylase inhibition activity of proanthocyanidins in unripe Manilkara zapota (chiku). | 2012 | J. Agric. Food Chem. | pmid:22394060 |
| Choi SK et al. | Suppression of oxidative stress by grape seed supplementation in rats. | 2012 | Nutr Res Pract | pmid:22413034 |
| Yang YJ et al. | Dietary flavan-3-ols intake and metabolic syndrome risk in Korean adults. | 2012 | Nutr Res Pract | pmid:22413043 |
| Al-Rejaie SS et al. | Gender difference following high cholesterol diet induced renal injury and the protective role of rutin and ascorbic acid combination in Wistar albino rats. | 2012 | Lipids Health Dis | pmid:22423898 |
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| Blaylock RL and Maroon J | Natural plant products and extracts that reduce immunoexcitotoxicity-associated neurodegeneration and promote repair within the central nervous system. | 2012 | Surg Neurol Int | pmid:22439110 |
| Margina D et al. | Quercetin and epigallocatechin gallate effects on the cell membranes biophysical properties correlate with their antioxidant potential. | 2012 | Gen. Physiol. Biophys. | pmid:22447830 |
| Sabhapondit S et al. | Diversity of catechin in northeast Indian tea cultivars. | 2012 | ScientificWorldJournal | pmid:22448135 |
| Roy S et al. | A novel combination of methotrexate and epigallocatechin attenuates the overexpression of pro-inflammatory cartilage cytokines and modulates antioxidant status in adjuvant arthritic rats. | 2012 | Inflammation | pmid:22453361 |
| Chen YY et al. | Ethanol extracts of fruiting bodies of Antrodia cinnamomea suppress CL1-5 human lung adenocarcinoma cells migration by inhibiting matrix metalloproteinase-2/9 through ERK, JNK, p38, and PI3K/Akt signaling pathways. | 2012 | Evid Based Complement Alternat Med | pmid:22454661 |
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| Joo SY et al. | Epigallocatechin-3-gallate Inhibits LPS-Induced NF-κB and MAPK Signaling Pathways in Bone Marrow-Derived Macrophages. | 2012 | Gut Liver | pmid:22570747 |
| Koppula S et al. | Reactive oxygen species and inhibitors of inflammatory enzymes, NADPH oxidase, and iNOS in experimental models of Parkinson's disease. | 2012 | Mediators Inflamm. | pmid:22577256 |
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| Margina D et al. | Quercetin and epigallocatechin gallate induce in vitro a dose-dependent stiffening and hyperpolarizing effect on the cell membrane of human mononuclear blood cells. | 2012 | Int J Mol Sci | pmid:22606013 |
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