(-)-Epigallocatechin is a lipid of Polyketides (PK) class. The involved functions are known as Protective Agents, inhibitors, Process, Drug Kinetics and Fermentation. (-)-epigallocatechin often locates in Hepatic, Blood, Membrane, Back and apical membrane. The associated genes with (-)-Epigallocatechin are ADRBK1 gene and FASTK Gene. The related lipids are 1,2-dilinolenoyl-3-(4-aminobutyryl)propane-1,2,3-triol. The related experimental models are Rodent Model and Transgenic Model.
To understand associated biological information of (-)-Epigallocatechin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
There are no associated biomedical information in the current reference collection.
We collected disease MeSH terms mapped to the references associated with (-)-Epigallocatechin
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Body Weight | D001835 | 333 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Hemolysis | D006461 | 131 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
| Mammary Neoplasms, Experimental | D008325 | 67 associated lipids |
| Liver Diseases | D008107 | 31 associated lipids |
| Glioblastoma | D005909 | 27 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
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| Function | Cross reference | Weighted score | Related literatures |
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| Lipid concept | Cross reference | Weighted score | Related literatures |
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| Gene | Cross reference | Weighted score | Related literatures |
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Rodent Model are used in the study 'Dietary (-)-epicatechin as a potent inhibitor of βγ-secretase amyloid precursor protein processing.' (Cox CJ et al., 2015) and Rodent Model are used in the study 'Effects of dosing condition on the oral bioavailability of green tea catechins after single-dose administration of Polyphenon E in healthy individuals.' (Chow HH et al., 2005).
Transgenic Model are used in the study 'Dietary (-)-epicatechin as a potent inhibitor of βγ-secretase amyloid precursor protein processing.' (Cox CJ et al., 2015).
| Model | Cross reference | Weighted score | Related literatures |
|---|
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Alemdaroglu NC et al. | Inhibition of folic acid uptake by catechins and tea extracts in Caco-2 cells. | 2007 | Planta Med. | pmid:17117344 |
| Koyama Y et al. | Effects of green tea on gene expression of hepatic gluconeogenic enzymes in vivo. | 2004 | Planta Med. | pmid:15549673 |
| Dauer A et al. | Polymeric proanthocyanidins from the bark of Hamamelis virginiana. | 2003 | Planta Med. | pmid:12567291 |
| Shim JS et al. | The effects of panduratin A isolated from Kaempferia pandurata on the expression of matrix metalloproteinase-1 and type-1 procollagen in human skin fibroblasts. | 2008 | Planta Med. | pmid:18253916 |
| Kuo YC et al. | Isolation and immunomodulatory effect of flavonoids from Syzygium samarangense. | 2004 | Planta Med. | pmid:15643565 |
| Kao CC et al. | Green tea catechins: inhibitors of glycerol-3-phosphate dehydrogenase. | 2010 | Planta Med. | pmid:19937554 |
| Kuzuhara T et al. | Green tea catechins inhibit the endonuclease activity of influenza A virus RNA polymerase. | 2009 | PLoS Curr | pmid:20025206 |
| Wang P et al. | Limitations of MTT and MTS-based assays for measurement of antiproliferative activity of green tea polyphenols. | 2010 | PLoS ONE | pmid:20419137 |
| Sun Z et al. | Phosphorylation of Nrf2 at multiple sites by MAP kinases has a limited contribution in modulating the Nrf2-dependent antioxidant response. | 2009 | PLoS ONE | pmid:19668370 |
| Fujimura Y et al. | Metabolomics-driven nutraceutical evaluation of diverse green tea cultivars. | 2011 | PLoS ONE | pmid:21853132 |