(-)-Epigallocatechin

(-)-Epigallocatechin is a lipid of Polyketides (PK) class. The involved functions are known as Protective Agents, inhibitors, Process, Drug Kinetics and Fermentation. (-)-epigallocatechin often locates in Hepatic, Blood, Membrane, Back and apical membrane. The associated genes with (-)-Epigallocatechin are ADRBK1 gene and FASTK Gene. The related lipids are 1,2-dilinolenoyl-3-(4-aminobutyryl)propane-1,2,3-triol. The related experimental models are Rodent Model and Transgenic Model.

Cross Reference

Introduction

To understand associated biological information of (-)-Epigallocatechin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with (-)-Epigallocatechin?

There are no associated biomedical information in the current reference collection.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with (-)-Epigallocatechin

MeSH term MeSH ID Detail
Body Weight D001835 333 associated lipids
Lung Neoplasms D008175 171 associated lipids
Adenocarcinoma D000230 166 associated lipids
Hemolysis D006461 131 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Liver Diseases D008107 31 associated lipids
Glioblastoma D005909 27 associated lipids
Total 8

PubChem Associated disorders and diseases

What pathways are associated with (-)-Epigallocatechin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with (-)-Epigallocatechin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with (-)-Epigallocatechin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with (-)-Epigallocatechin?

Related references are published most in these journals:

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What genes are associated with (-)-Epigallocatechin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with (-)-Epigallocatechin?

Rodent Model

Rodent Model are used in the study 'Dietary (-)-epicatechin as a potent inhibitor of βγ-secretase amyloid precursor protein processing.' (Cox CJ et al., 2015) and Rodent Model are used in the study 'Effects of dosing condition on the oral bioavailability of green tea catechins after single-dose administration of Polyphenon E in healthy individuals.' (Chow HH et al., 2005).

Transgenic Model

Transgenic Model are used in the study 'Dietary (-)-epicatechin as a potent inhibitor of βγ-secretase amyloid precursor protein processing.' (Cox CJ et al., 2015).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with (-)-Epigallocatechin

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Authors Title Published Journal PubMed Link
Ikeda I et al. Tea catechins decrease micellar solubility and intestinal absorption of cholesterol in rats. 1992 Biochim. Biophys. Acta pmid:1643098
Ikigai H et al. Bactericidal catechins damage the lipid bilayer. 1993 Biochim. Biophys. Acta pmid:8466924
Amici M et al. Wheat sprout extract induces changes on 20S proteasomes functionality. 2008 Biochimie pmid:18190797
Dai F et al. Antioxidant synergism of green tea polyphenols with alpha-tocopherol and L-ascorbic acid in SDS micelles. 2008 Biochimie pmid:18554517
Luximon-Ramma A et al. Assessment of the polyphenolic composition of the organic extracts of Mauritian black teas: a potential contributor to their antioxidant functions. 2006 Biofactors pmid:17012766
Suganuma M et al. Mechanisms of cancer prevention by tea polyphenols based on inhibition of TNF-alpha expression. 2000 Biofactors pmid:11237202
Inaba H et al. Comparative examination of anti-proliferative activities of (-)-epigallocatechin gallate and (--)-epigallocatechin against HCT116 colorectal carcinoma cells. 2008 Biol. Pharm. Bull. pmid:18175946
Furuno K et al. The contribution of the pyrogallol moiety to the superoxide radical scavenging activity of flavonoids. 2002 Biol. Pharm. Bull. pmid:11824550
Kang HW et al. Isolation and characterization of alkyl peroxy radical scavenging compound from leaves of Laurus nobilis. 2002 Biol. Pharm. Bull. pmid:11824536
Yokozawa T et al. Study on the components of luobuma with peroxynitrite-scavenging activity. 2002 Biol. Pharm. Bull. pmid:12081141