(-)-Epigallocatechin is a lipid of Polyketides (PK) class. The involved functions are known as Protective Agents, inhibitors, Process, Drug Kinetics and Fermentation. (-)-epigallocatechin often locates in Hepatic, Blood, Membrane, Back and apical membrane. The associated genes with (-)-Epigallocatechin are ADRBK1 gene and FASTK Gene. The related lipids are 1,2-dilinolenoyl-3-(4-aminobutyryl)propane-1,2,3-triol. The related experimental models are Rodent Model and Transgenic Model.
To understand associated biological information of (-)-Epigallocatechin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
There are no associated biomedical information in the current reference collection.
We collected disease MeSH terms mapped to the references associated with (-)-Epigallocatechin
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Adenocarcinoma | D000230 | 166 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Glioblastoma | D005909 | 27 associated lipids |
| Hemolysis | D006461 | 131 associated lipids |
| Liver Diseases | D008107 | 31 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Mammary Neoplasms, Experimental | D008325 | 67 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
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| Function | Cross reference | Weighted score | Related literatures |
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| Lipid concept | Cross reference | Weighted score | Related literatures |
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| Gene | Cross reference | Weighted score | Related literatures |
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Rodent Model are used in the study 'Dietary (-)-epicatechin as a potent inhibitor of βγ-secretase amyloid precursor protein processing.' (Cox CJ et al., 2015) and Rodent Model are used in the study 'Effects of dosing condition on the oral bioavailability of green tea catechins after single-dose administration of Polyphenon E in healthy individuals.' (Chow HH et al., 2005).
Transgenic Model are used in the study 'Dietary (-)-epicatechin as a potent inhibitor of βγ-secretase amyloid precursor protein processing.' (Cox CJ et al., 2015).
| Model | Cross reference | Weighted score | Related literatures |
|---|
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Wang Z et al. | Bioactivity-guided identification and cell signaling technology to delineate the lactate dehydrogenase A inhibition effects of Spatholobus suberectus on breast cancer. | 2013 | PLoS ONE | pmid:23457597 |
| Ly BT et al. | Inhibition of FLT3 expression by green tea catechins in FLT3 mutated-AML cells. | 2013 | PLoS ONE | pmid:23840454 |
| Teixeira N et al. | Structural features of copigmentation of oenin with different polyphenol copigments. | 2013 | J. Agric. Food Chem. | pmid:23829187 |
| Bai LP et al. | Aminoglycosylation can enhance the G-quadruplex binding activity of epigallocatechin. | 2013 | PLoS ONE | pmid:23335983 |
| Li F et al. | Inhibitory effect of catechin-related compounds on renin activity. | 2013 | Biomed. Res. | pmid:23782751 |
| Hong YH et al. | Enzymatic improvement in the polyphenol extractability and antioxidant activity of green tea extracts. | 2013 | Biosci. Biotechnol. Biochem. | pmid:23291774 |
| Zhao L et al. | Green tea catechins quench the fluorescence of bacteria-conjugated Alexa fluor dyes. | 2013 | Inflamm Allergy Drug Targets | pmid:24011199 |
| Lee LS et al. | Optimization of ultrasonic extraction of phenolic antioxidants from green tea using response surface methodology. | 2013 | Molecules | pmid:24184822 |
| Chen XQ et al. | Blood anticoagulation and antiplatelet activity of green tea (-)-epigallocatechin (EGC) in mice. | 2013 | Food Funct | pmid:24056410 |
| Olšovská J et al. | Ultra-high-performance liquid chromatography profiling method for chemical screening of proanthocyanidins in Czech hops. | 2013 | Talanta | pmid:24148495 |