(-)-Epigallocatechin is a lipid of Polyketides (PK) class. The involved functions are known as Protective Agents, inhibitors, Process, Drug Kinetics and Fermentation. (-)-epigallocatechin often locates in Hepatic, Blood, Membrane, Back and apical membrane. The associated genes with (-)-Epigallocatechin are ADRBK1 gene and FASTK Gene. The related lipids are 1,2-dilinolenoyl-3-(4-aminobutyryl)propane-1,2,3-triol. The related experimental models are Rodent Model and Transgenic Model.
To understand associated biological information of (-)-Epigallocatechin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
There are no associated biomedical information in the current reference collection.
We collected disease MeSH terms mapped to the references associated with (-)-Epigallocatechin
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Adenocarcinoma | D000230 | 166 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Glioblastoma | D005909 | 27 associated lipids |
| Hemolysis | D006461 | 131 associated lipids |
| Liver Diseases | D008107 | 31 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Mammary Neoplasms, Experimental | D008325 | 67 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
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| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
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| Gene | Cross reference | Weighted score | Related literatures |
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Rodent Model are used in the study 'Dietary (-)-epicatechin as a potent inhibitor of βγ-secretase amyloid precursor protein processing.' (Cox CJ et al., 2015) and Rodent Model are used in the study 'Effects of dosing condition on the oral bioavailability of green tea catechins after single-dose administration of Polyphenon E in healthy individuals.' (Chow HH et al., 2005).
Transgenic Model are used in the study 'Dietary (-)-epicatechin as a potent inhibitor of βγ-secretase amyloid precursor protein processing.' (Cox CJ et al., 2015).
| Model | Cross reference | Weighted score | Related literatures |
|---|
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
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| Song DK et al. | Polyphenol (-)-epigallocatechin gallate during ischemia limits infarct size via mitochondrial K(ATP) channel activation in isolated rat hearts. | 2010 | J. Korean Med. Sci. | pmid:20191036 |
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| Kim CJ et al. | Polyphenol (-)-epigallocatechin gallate targeting myocardial reperfusion limits infarct size and improves cardiac function. | 2010 | Korean J Anesthesiol | pmid:20498796 |
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| Miyata M et al. | The crystal structure of the green tea polyphenol (-)-epigallocatechin gallate-transthyretin complex reveals a novel binding site distinct from the thyroxine binding site. | 2010 | Biochemistry | pmid:20565072 |
| Vu HA et al. | Green tea epigallocatechin gallate exhibits anticancer effect in human pancreatic carcinoma cells via the inhibition of both focal adhesion kinase and insulin-like growth factor-I receptor. | 2010 | J. Biomed. Biotechnol. | pmid:21318151 |
| Karth A et al. | A case report of atrial fibrillation potentially induced by hydroxycut: a multicomponent dietary weight loss supplement devoid of sympathomimetic amines. | 2010 | J Pharm Pract | pmid:21507821 |
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| Hellmann JK et al. | Synergistic and additive effects of epigallocatechin gallate and digitonin on Plasmodium sporozoite survival and motility. | 2010 | PLoS ONE | pmid:20072627 |
| Luo T et al. | (-)-Epigallocatechin gallate sensitizes breast cancer cells to paclitaxel in a murine model of breast carcinoma. | 2010 | Breast Cancer Res. | pmid:20078855 |
| Ashihara H et al. | Distribution and biosynthesis of flavan-3-ols in Camellia sinensis seedlings and expression of genes encoding biosynthetic enzymes. | 2010 | Phytochemistry | pmid:20189205 |
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| Mullen W et al. | Identification of metabolites in human plasma and urine after consumption of a polyphenol-rich juice drink. | 2010 | J. Agric. Food Chem. | pmid:20088510 |
| Oliveras G et al. | Novel anti-fatty acid synthase compounds with anti-cancer activity in HER2+ breast cancer. | 2010 | Ann. N. Y. Acad. Sci. | pmid:20973802 |
| Ranjith-Kumar CT et al. | Green tea catechin, epigallocatechin gallate, suppresses signaling by the dsRNA innate immune receptor RIG-I. | 2010 | PLoS ONE | pmid:20877565 |
| Gundimeda U et al. | Green tea polyphenols potentiate the action of nerve growth factor to induce neuritogenesis: possible role of reactive oxygen species. | 2010 | J. Neurosci. Res. | pmid:20936703 |
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| Chan CM et al. | Effects of (-)-epigallocatechin gallate on RPE cell migration and adhesion. | 2010 | Mol. Vis. | pmid:20376327 |
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| Lin SF et al. | Synthesis and structure-activity relationship of 3-O-acylated (-)-epigallocatechins as 5α-reductase inhibitors. | 2010 | Eur J Med Chem | pmid:21044810 |
| Ikeda H et al. | [Mechanism of interaction between risperidone and tea catechin(1)complex formation of risperidone with epigallocatechin gallate]. | 2010 | Yakugaku Zasshi | pmid:21048420 |
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