(-)-Epigallocatechin is a lipid of Polyketides (PK) class. The involved functions are known as Protective Agents, inhibitors, Process, Drug Kinetics and Fermentation. (-)-epigallocatechin often locates in Hepatic, Blood, Membrane, Back and apical membrane. The associated genes with (-)-Epigallocatechin are ADRBK1 gene and FASTK Gene. The related lipids are 1,2-dilinolenoyl-3-(4-aminobutyryl)propane-1,2,3-triol. The related experimental models are Rodent Model and Transgenic Model.
To understand associated biological information of (-)-Epigallocatechin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
There are no associated biomedical information in the current reference collection.
We collected disease MeSH terms mapped to the references associated with (-)-Epigallocatechin
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Adenocarcinoma | D000230 | 166 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Glioblastoma | D005909 | 27 associated lipids |
| Hemolysis | D006461 | 131 associated lipids |
| Liver Diseases | D008107 | 31 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Mammary Neoplasms, Experimental | D008325 | 67 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
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| Function | Cross reference | Weighted score | Related literatures |
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| Lipid concept | Cross reference | Weighted score | Related literatures |
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| Gene | Cross reference | Weighted score | Related literatures |
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Rodent Model are used in the study 'Dietary (-)-epicatechin as a potent inhibitor of βγ-secretase amyloid precursor protein processing.' (Cox CJ et al., 2015) and Rodent Model are used in the study 'Effects of dosing condition on the oral bioavailability of green tea catechins after single-dose administration of Polyphenon E in healthy individuals.' (Chow HH et al., 2005).
Transgenic Model are used in the study 'Dietary (-)-epicatechin as a potent inhibitor of βγ-secretase amyloid precursor protein processing.' (Cox CJ et al., 2015).
| Model | Cross reference | Weighted score | Related literatures |
|---|
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Fujimura Y et al. | A tea catechin suppresses the expression of the high-affinity IgE receptor Fc epsilon RI in human basophilic KU812 cells. | 2001 | J. Agric. Food Chem. | pmid:11368631 |
| Kumamoto M et al. | Effects of pH and metal ions on antioxidative activities of catechins. | 2001 | Biosci. Biotechnol. Biochem. | pmid:11272815 |
| Krul C et al. | Antimutagenic activity of green tea and black tea extracts studied in a dynamic in vitro gastrointestinal model. | 2001 | Mutat. Res. | pmid:11239964 |
| Chung LY et al. | Induction of apoptosis by green tea catechins in human prostate cancer DU145 cells. | 2001 | Life Sci. | pmid:11228105 |
| Chen Z et al. | Degradation of green tea catechins in tea drinks. | 2001 | J. Agric. Food Chem. | pmid:11170614 |
| Crouvezier S et al. | The effects of phenolic components of tea on the production of pro- and anti-inflammatory cytokines by human leukocytes in vitro. | 2001 | Cytokine | pmid:11243706 |
| Yoshioka H et al. | Spin-trapping study on the hydroxyl radical formed from a tea catechin-Cu(II) system. | 2001 | Biosci. Biotechnol. Biochem. | pmid:11577706 |
| Zhu BT et al. | Rapid conversion of tea catechins to monomethylated products by rat liver cytosolic catechol-O-methyltransferase. | 2001 | Xenobiotica | pmid:11780762 |
| Van Amelsvoort JM et al. | Plasma concentrations of individual tea catechins after a single oral dose in humans. | 2001 | Xenobiotica | pmid:11780763 |
| Baumann D et al. | A simple isolation method for the major catechins in green tea using high-speed countercurrent chromatography. | 2001 | J. Nat. Prod. | pmid:11277755 |
| Opare Kennedy D et al. | Growth inhibitory effect of green tea extract and (-)-epigallocatechin in Ehrlich ascites tumor cells involves a cellular thiol-dependent activation of mitogenic-activated protein kinases. | 2001 | Chem. Biol. Interact. | pmid:11311209 |
| Bhatia N and Agarwal R | Detrimental effect of cancer preventive phytochemicals silymarin, genistein and epigallocatechin 3-gallate on epigenetic events in human prostate carcinoma DU145 cells. | 2001 | Prostate | pmid:11170137 |
| Smith DM and Dou QP | Green tea polyphenol epigallocatechin inhibits DNA replication and consequently induces leukemia cell apoptosis. | 2001 | Int. J. Mol. Med. | pmid:11351279 |
| Zhu M et al. | Pharmacokinetics and system linearity of tea catechins in rat. | 2001 | Xenobiotica | pmid:11334265 |
| Warden BA et al. | Catechins are bioavailable in men and women drinking black tea throughout the day. | 2001 | J. Nutr. | pmid:11385060 |
| Bertoldi M et al. | Green tea polyphenols: novel irreversible inhibitors of dopa decarboxylase. | 2001 | Biochem. Biophys. Res. Commun. | pmid:11374875 |
| Elmets CA et al. | Cutaneous photoprotection from ultraviolet injury by green tea polyphenols. | 2001 | J. Am. Acad. Dermatol. | pmid:11209110 |
| Yonezawa Y et al. | Mut-Test to detect substances suppressing spontaneous mutation due to oxidative damage. | 2001 | Mutat. Res. | pmid:11152968 |
| Tang FY and Meydani M | Green tea catechins and vitamin E inhibit angiogenesis of human microvascular endothelial cells through suppression of IL-8 production. | 2001 | Nutr Cancer | pmid:12094614 |
| Tsuchiya H | Stereospecificity in membrane effects of catechins. | 2001 | Chem. Biol. Interact. | pmid:11248221 |