(-)-Epigallocatechin

(-)-Epigallocatechin is a lipid of Polyketides (PK) class. The involved functions are known as Protective Agents, inhibitors, Process, Drug Kinetics and Fermentation. (-)-epigallocatechin often locates in Hepatic, Blood, Membrane, Back and apical membrane. The associated genes with (-)-Epigallocatechin are ADRBK1 gene and FASTK Gene. The related lipids are 1,2-dilinolenoyl-3-(4-aminobutyryl)propane-1,2,3-triol. The related experimental models are Rodent Model and Transgenic Model.

Cross Reference

Introduction

To understand associated biological information of (-)-Epigallocatechin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with (-)-Epigallocatechin?

There are no associated biomedical information in the current reference collection.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with (-)-Epigallocatechin

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Adenocarcinoma D000230 166 associated lipids
Lung Neoplasms D008175 171 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Body Weight D001835 333 associated lipids
Liver Diseases D008107 31 associated lipids
Glioblastoma D005909 27 associated lipids
Total 8

PubChem Associated disorders and diseases

What pathways are associated with (-)-Epigallocatechin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with (-)-Epigallocatechin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with (-)-Epigallocatechin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with (-)-Epigallocatechin?

Related references are published most in these journals:

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What genes are associated with (-)-Epigallocatechin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with (-)-Epigallocatechin?

Rodent Model

Rodent Model are used in the study 'Dietary (-)-epicatechin as a potent inhibitor of βγ-secretase amyloid precursor protein processing.' (Cox CJ et al., 2015) and Rodent Model are used in the study 'Effects of dosing condition on the oral bioavailability of green tea catechins after single-dose administration of Polyphenon E in healthy individuals.' (Chow HH et al., 2005).

Transgenic Model

Transgenic Model are used in the study 'Dietary (-)-epicatechin as a potent inhibitor of βγ-secretase amyloid precursor protein processing.' (Cox CJ et al., 2015).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with (-)-Epigallocatechin

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Authors Title Published Journal PubMed Link
Stammler G and Volm M Green tea catechins (EGCG and EGC) have modulating effects on the activity of doxorubicin in drug-resistant cell lines. 1997 Anticancer Drugs pmid:9095331
Shin SC and Choi JS Effects of epigallocatechin gallate on the oral bioavailability and pharmacokinetics of tamoxifen and its main metabolite, 4-hydroxytamoxifen, in rats. 2009 Anticancer Drugs pmid:19491656
Chisholm K et al. Tamoxifen and epigallocatechin gallate are synergistically cytotoxic to MDA-MB-231 human breast cancer cells. 2004 Anticancer Drugs pmid:15457130
Ghiringhelli F et al. Immunomodulation and anti-inflammatory roles of polyphenols as anticancer agents. 2012 Anticancer Agents Med Chem pmid:22292769
Oliveras G et al. Novel anti-fatty acid synthase compounds with anti-cancer activity in HER2+ breast cancer. 2010 Ann. N. Y. Acad. Sci. pmid:20973802
Lee SJ et al. Phenolic phytochemicals derived from red pine (Pinus densiflora) inhibit the invasion and migration of SK-Hep-1 human hepatocellular carcinoma cells. 2007 Ann. N. Y. Acad. Sci. pmid:17404067
Jovanovic SV and Simic MG Antioxidants in nutrition. 2000 Ann. N. Y. Acad. Sci. pmid:10863550
Butnariu M Detection of the polyphenolic components in Ribes nigrum L. 2014 Ann Agric Environ Med pmid:24742033
Patel T et al. Anti inflammatory activity of Myrica nagi Linn. Bark. 2011 Anc Sci Life pmid:22557437
Yang B et al. Determination of catechins in human urine subsequent to tea ingestion by high-performance liquid chromatography with electrochemical detection. 2000 Anal. Biochem. pmid:10929811