(-)-Epigallocatechin is a lipid of Polyketides (PK) class. The involved functions are known as Protective Agents, inhibitors, Process, Drug Kinetics and Fermentation. (-)-epigallocatechin often locates in Hepatic, Blood, Membrane, Back and apical membrane. The associated genes with (-)-Epigallocatechin are ADRBK1 gene and FASTK Gene. The related lipids are 1,2-dilinolenoyl-3-(4-aminobutyryl)propane-1,2,3-triol. The related experimental models are Rodent Model and Transgenic Model.
To understand associated biological information of (-)-Epigallocatechin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
There are no associated biomedical information in the current reference collection.
We collected disease MeSH terms mapped to the references associated with (-)-Epigallocatechin
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
| Mammary Neoplasms, Experimental | D008325 | 67 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Liver Diseases | D008107 | 31 associated lipids |
| Glioblastoma | D005909 | 27 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
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| Lipid concept | Cross reference | Weighted score | Related literatures |
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| Gene | Cross reference | Weighted score | Related literatures |
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Rodent Model are used in the study 'Dietary (-)-epicatechin as a potent inhibitor of βγ-secretase amyloid precursor protein processing.' (Cox CJ et al., 2015) and Rodent Model are used in the study 'Effects of dosing condition on the oral bioavailability of green tea catechins after single-dose administration of Polyphenon E in healthy individuals.' (Chow HH et al., 2005).
Transgenic Model are used in the study 'Dietary (-)-epicatechin as a potent inhibitor of βγ-secretase amyloid precursor protein processing.' (Cox CJ et al., 2015).
| Model | Cross reference | Weighted score | Related literatures |
|---|
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Zhang YN et al. | Improving the sweet aftertaste of green tea infusion with tannase. | 2016 | Food Chem | pmid:26304374 |
| Xia G et al. | Tannase-mediated biotransformation assisted separation and purification of theaflavin and epigallocatechin by high speed counter current chromatography and preparative high performance liquid chromatography: A comparative study. | 2016 | Microsc. Res. Tech. | pmid:27389804 |
| Matsuo Y et al. | Stereochemistry of the Black Tea Pigments Theacitrins A and C. | 2016 | J. Nat. Prod. | pmid:26689950 |
| Fan FY et al. | Differential behaviors of tea catechins under thermal processing: Formation of non-enzymatic oligomers. | 2016 | Food Chem | pmid:26593500 |
| Abourashed EA et al. | Content Variation of Catechin Markers, Total Phenolics and Caffeine in Green Tea Dietary Supplements. | 2016 | J Diet Suppl | pmid:25299974 |
| Takagaki A and Nanjo F | Effects of Metabolites Produced from (-)-Epigallocatechin Gallate by Rat Intestinal Bacteria on Angiotensin I-Converting Enzyme Activity and Blood Pressure in Spontaneously Hypertensive Rats. | 2015 | J. Agric. Food Chem. | pmid:26323573 |
| Ramasamy C | Potential natural antioxidants: adjuvant effect of green tea polyphenols in periodontal infections. | 2015 | Infect Disord Drug Targets | pmid:26321324 |
| Farhan M et al. | Mobilization of copper ions in human peripheral lymphocytes by catechins leading to oxidative DNA breakage: A structure activity study. | 2015 | Arch. Biochem. Biophys. | pmid:26142371 |
| López-Gutiérrez N et al. | Identification and quantification of phytochemicals in nutraceutical products from green tea by UHPLC-Orbitrap-MS. | 2015 | Food Chem | pmid:25466066 |
| Song BJ et al. | Thermal degradation of green tea flavan-3-ols and formation of hetero- and homocatechin dimers in model dairy beverages. | 2015 | Food Chem | pmid:25466027 |
| Wong IL et al. | Potent and Nontoxic Chemosensitizer of P-Glycoprotein-Mediated Multidrug Resistance in Cancer: Synthesis and Evaluation of Methylated Epigallocatechin, Gallocatechin, and Dihydromyricetin Derivatives. | 2015 | J. Med. Chem. | pmid:25985195 |
| Takagaki A and Nanjo F | Bioconversion of (-)-epicatechin, (+)-epicatechin, (-)-catechin, and (+)-catechin by (-)-epigallocatechin-metabolizing bacteria. | 2015 | Biol. Pharm. Bull. | pmid:25947926 |
| Kaneko YK et al. | Structure-dependent inhibitory effects of green tea catechins on insulin secretion from pancreatic β-cells. | 2015 | Biol. Pharm. Bull. | pmid:25757931 |
| Takagaki A and Nanjo F | Biotransformation of (-)-epigallocatechin and (-)-gallocatechin by intestinal bacteria involved in isoflavone metabolism. | 2015 | Biol. Pharm. Bull. | pmid:25747993 |
| Butler LM et al. | Urinary biomarkers of catechins and risk of hepatocellular carcinoma in the Shanghai Cohort Study. | 2015 | Am. J. Epidemiol. | pmid:25713334 |
| Zhang Y et al. | Simultaneous quantification of ten constituents of Xanthoceras sorbifolia Bunge using UHPLC-MS methods and evaluation of their radical scavenging, DNA scission protective, and α-glucosidase inhibitory activities. | 2015 | Chin J Nat Med | pmid:26614463 |
| Macomber L et al. | Reduction of urease activity by interaction with the flap covering the active site. | 2015 | J Chem Inf Model | pmid:25594724 |
| Cox CJ et al. | Dietary (-)-epicatechin as a potent inhibitor of βγ-secretase amyloid precursor protein processing. | 2015 | Neurobiol. Aging | pmid:25316600 |
| Ferrer-Gallego R et al. | Characterization of Sensory Properties of Flavanols - A Molecular Dynamic Approach. | 2015 | Chem. Senses | pmid:25934978 |
| Cui Y et al. | Protective effects of polyphenols-enriched extract from Huangshan Maofeng green tea against CCl4-induced liver injury in mice. | 2014 | Chem. Biol. Interact. | pmid:24973642 |