(-)-Epigallocatechin is a lipid of Polyketides (PK) class. The involved functions are known as Protective Agents, inhibitors, Process, Drug Kinetics and Fermentation. (-)-epigallocatechin often locates in Hepatic, Blood, Membrane, Back and apical membrane. The associated genes with (-)-Epigallocatechin are ADRBK1 gene and FASTK Gene. The related lipids are 1,2-dilinolenoyl-3-(4-aminobutyryl)propane-1,2,3-triol. The related experimental models are Rodent Model and Transgenic Model.
To understand associated biological information of (-)-Epigallocatechin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
There are no associated biomedical information in the current reference collection.
We collected disease MeSH terms mapped to the references associated with (-)-Epigallocatechin
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
| Mammary Neoplasms, Experimental | D008325 | 67 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Liver Diseases | D008107 | 31 associated lipids |
| Glioblastoma | D005909 | 27 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
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| Function | Cross reference | Weighted score | Related literatures |
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| Lipid concept | Cross reference | Weighted score | Related literatures |
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| Gene | Cross reference | Weighted score | Related literatures |
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Rodent Model are used in the study 'Dietary (-)-epicatechin as a potent inhibitor of βγ-secretase amyloid precursor protein processing.' (Cox CJ et al., 2015) and Rodent Model are used in the study 'Effects of dosing condition on the oral bioavailability of green tea catechins after single-dose administration of Polyphenon E in healthy individuals.' (Chow HH et al., 2005).
Transgenic Model are used in the study 'Dietary (-)-epicatechin as a potent inhibitor of βγ-secretase amyloid precursor protein processing.' (Cox CJ et al., 2015).
| Model | Cross reference | Weighted score | Related literatures |
|---|
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Theisen LL and Muller CP | EPs® 7630 (Umckaloabo®), an extract from Pelargonium sidoides roots, exerts anti-influenza virus activity in vitro and in vivo. | 2012 | Antiviral Res. | pmid:22475498 |
| Nakashima H et al. | Inhibition of human immunodeficiency viral replication by tannins and related compounds. | 1992 | Antiviral Res. | pmid:1416904 |
| Song JM et al. | Antiviral effect of catechins in green tea on influenza virus. | 2005 | Antiviral Res. | pmid:16137775 |
| Fathima A and Rao JR | Selective toxicity of Catechin-a natural flavonoid towards bacteria. | 2016 | Appl. Microbiol. Biotechnol. | pmid:27052380 |
| Kondo K et al. | Mechanistic studies of catechins as antioxidants against radical oxidation. | 1999 | Arch. Biochem. Biophys. | pmid:9917331 |
| Farhan M et al. | Mobilization of copper ions in human peripheral lymphocytes by catechins leading to oxidative DNA breakage: A structure activity study. | 2015 | Arch. Biochem. Biophys. | pmid:26142371 |
| Roginsky V | Chain-breaking antioxidant activity of natural polyphenols as determined during the chain oxidation of methyl linoleate in Triton X-100 micelles. | 2003 | Arch. Biochem. Biophys. | pmid:12781778 |
| Hagerman AE et al. | Radical chemistry of epigallocatechin gallate and its relevance to protein damage. | 2003 | Arch. Biochem. Biophys. | pmid:12745262 |
| Bors W et al. | Electron paramagnetic resonance studies of radical species of proanthocyanidins and gallate esters. | 2000 | Arch. Biochem. Biophys. | pmid:10666317 |
| Nie G et al. | Distinct effects of tea catechins on 6-hydroxydopamine-induced apoptosis in PC12 cells. | 2002 | Arch. Biochem. Biophys. | pmid:11747313 |