(-)-Epigallocatechin is a lipid of Polyketides (PK) class. The involved functions are known as Protective Agents, inhibitors, Process, Drug Kinetics and Fermentation. (-)-epigallocatechin often locates in Hepatic, Blood, Membrane, Back and apical membrane. The associated genes with (-)-Epigallocatechin are ADRBK1 gene and FASTK Gene. The related lipids are 1,2-dilinolenoyl-3-(4-aminobutyryl)propane-1,2,3-triol. The related experimental models are Rodent Model and Transgenic Model.
To understand associated biological information of (-)-Epigallocatechin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
There are no associated biomedical information in the current reference collection.
We collected disease MeSH terms mapped to the references associated with (-)-Epigallocatechin
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
| Mammary Neoplasms, Experimental | D008325 | 67 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Liver Diseases | D008107 | 31 associated lipids |
| Glioblastoma | D005909 | 27 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
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| Function | Cross reference | Weighted score | Related literatures |
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| Lipid concept | Cross reference | Weighted score | Related literatures |
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| Gene | Cross reference | Weighted score | Related literatures |
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Rodent Model are used in the study 'Dietary (-)-epicatechin as a potent inhibitor of βγ-secretase amyloid precursor protein processing.' (Cox CJ et al., 2015) and Rodent Model are used in the study 'Effects of dosing condition on the oral bioavailability of green tea catechins after single-dose administration of Polyphenon E in healthy individuals.' (Chow HH et al., 2005).
Transgenic Model are used in the study 'Dietary (-)-epicatechin as a potent inhibitor of βγ-secretase amyloid precursor protein processing.' (Cox CJ et al., 2015).
| Model | Cross reference | Weighted score | Related literatures |
|---|
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Bors W et al. | Electron paramagnetic resonance studies of radical species of proanthocyanidins and gallate esters. | 2000 | Arch. Biochem. Biophys. | pmid:10666317 |
| Lee MH et al. | EBV DNA polymerase inhibition of tannins from Eugenia uniflora. | 2000 | Cancer Lett. | pmid:10806300 |
| Zhu N et al. | Identification of oxidation products of (-)-epigallocatechin gallate and (-)-epigallocatechin with H(2)O(2). | 2000 | J. Agric. Food Chem. | pmid:10775337 |
| Yee YK and Koo MW | Anti-Helicobacter pylori activity of Chinese tea: in vitro study. | 2000 | Aliment. Pharmacol. Ther. | pmid:10792128 |
| Uesato S et al. | Antitumor promoting activities of 3-O-acyl-(-)epigallocatechins. | 2000 | Bioorg. Med. Chem. Lett. | pmid:10937722 |
| Jovanovic SV and Simic MG | Antioxidants in nutrition. | 2000 | Ann. N. Y. Acad. Sci. | pmid:10863550 |
| Yang B et al. | Determination of catechins in human urine subsequent to tea ingestion by high-performance liquid chromatography with electrochemical detection. | 2000 | Anal. Biochem. | pmid:10929811 |
| Long LH et al. | Artifacts in cell culture: rapid generation of hydrogen peroxide on addition of (-)-epigallocatechin, (-)-epigallocatechin gallate, (+)-catechin, and quercetin to commonly used cell culture media. | 2000 | Biochem. Biophys. Res. Commun. | pmid:10873562 |
| Liu Z et al. | Antioxidative effects of green tea polyphenols on free radical initiated and photosensitized peroxidation of human low density lipoprotein. | 2000 | Chem. Phys. Lipids | pmid:10878235 |
| Abe I et al. | Green tea polyphenols: novel and potent inhibitors of squalene epoxidase. | 2000 | Biochem. Biophys. Res. Commun. | pmid:10679280 |
| Tanaka T et al. | Oxidation and epimerization of epigallocatechin in banana fruits. | 2000 | Phytochemistry | pmid:10680189 |
| Hong J et al. | Effects of purified green and black tea polyphenols on cyclooxygenase- and lipoxygenase-dependent metabolism of arachidonic acid in human colon mucosa and colon tumor tissues. | 2001 | Biochem. Pharmacol. | pmid:11705450 |
| Chow HH et al. | Phase I pharmacokinetic study of tea polyphenols following single-dose administration of epigallocatechin gallate and polyphenon E. | 2001 | Cancer Epidemiol. Biomarkers Prev. | pmid:11205489 |
| Wang LQ et al. | The heterocyclic ring fission and dehydroxylation of catechins and related compounds by Eubacterium sp. strain SDG-2, a human intestinal bacterium. | 2001 | Chem. Pharm. Bull. | pmid:11767089 |
| Beppu M et al. | Water-soluble antioxidants inhibit macrophage recognition of oxidized erythrocytes. | 2001 | Biol. Pharm. Bull. | pmid:11379784 |
| Meng X et al. | Formation and identification of 4'-O-methyl-(-)-epigallocatechin in humans. | 2001 | Drug Metab. Dispos. | pmid:11353745 |
| Kennedy JA et al. | Composition of grape skin proanthocyanidins at different stages of berry development. | 2001 | J. Agric. Food Chem. | pmid:11714327 |
| Jin CF et al. | Different effects of five catechins on 6-hydroxydopamine-induced apoptosis in PC12 cells. | 2001 | J. Agric. Food Chem. | pmid:11743804 |
| Tanaka T et al. | Two types of oxidative dimerization of the black tea polyphenol theaflavin. | 2001 | J. Agric. Food Chem. | pmid:11743764 |
| Anderson RF et al. | Green tea catechins partially protect DNA from (.)OH radical-induced strand breaks and base damage through fast chemical repair of DNA radicals. | 2001 | Carcinogenesis | pmid:11470748 |