(-)-Epigallocatechin is a lipid of Polyketides (PK) class. The involved functions are known as Protective Agents, inhibitors, Process, Drug Kinetics and Fermentation. (-)-epigallocatechin often locates in Hepatic, Blood, Membrane, Back and apical membrane. The associated genes with (-)-Epigallocatechin are ADRBK1 gene and FASTK Gene. The related lipids are 1,2-dilinolenoyl-3-(4-aminobutyryl)propane-1,2,3-triol. The related experimental models are Rodent Model and Transgenic Model.
To understand associated biological information of (-)-Epigallocatechin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
There are no associated biomedical information in the current reference collection.
We collected disease MeSH terms mapped to the references associated with (-)-Epigallocatechin
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
| Mammary Neoplasms, Experimental | D008325 | 67 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Liver Diseases | D008107 | 31 associated lipids |
| Glioblastoma | D005909 | 27 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
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| Function | Cross reference | Weighted score | Related literatures |
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| Lipid concept | Cross reference | Weighted score | Related literatures |
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| Gene | Cross reference | Weighted score | Related literatures |
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Rodent Model are used in the study 'Dietary (-)-epicatechin as a potent inhibitor of βγ-secretase amyloid precursor protein processing.' (Cox CJ et al., 2015) and Rodent Model are used in the study 'Effects of dosing condition on the oral bioavailability of green tea catechins after single-dose administration of Polyphenon E in healthy individuals.' (Chow HH et al., 2005).
Transgenic Model are used in the study 'Dietary (-)-epicatechin as a potent inhibitor of βγ-secretase amyloid precursor protein processing.' (Cox CJ et al., 2015).
| Model | Cross reference | Weighted score | Related literatures |
|---|
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Harakeh S et al. | Effects of nutrients on matrix metalloproteinases in human T-lymphotropic virus type 1 positive and negative malignant T-lymphocytes. | 2014 | Int. J. Oncol. | pmid:25189759 |
| Mirasoli M et al. | Electronic nose and chiral-capillary electrophoresis in evaluation of the quality changes in commercial green tea leaves during a long-term storage. | 2014 | Talanta | pmid:25127562 |
| Murphy A et al. | Impact of antioxidants on the ability of phenolic phytochemicals to kill HCT116 colon cancer cells. | 2014 | Free Radic. Res. | pmid:24256565 |
| Yoshino S et al. | Effect of emulsification on the skin permeation and UV protection of catechin. | 2014 | Pharm Dev Technol | pmid:23639253 |
| Takagaki A et al. | Isolation and characterization of rat intestinal bacteria involved in biotransformation of (-)-epigallocatechin. | 2014 | Arch. Microbiol. | pmid:24947740 |
| Suedee A et al. | Anti-HIV-1 integrase activity of Mimusops elengi leaf extracts. | 2014 | Pharm Biol | pmid:24033292 |
| Xiao YH et al. | Transcriptome and biochemical analyses revealed a detailed proanthocyanidin biosynthesis pathway in brown cotton fiber. | 2014 | PLoS ONE | pmid:24466041 |
| Mocanu MM et al. | Epigallocatechin 3-O-gallate induces 67 kDa laminin receptor-mediated cell death accompanied by downregulation of ErbB proteins and altered lipid raft clustering in mammary and epidermoid carcinoma cells. | 2014 | J. Nat. Prod. | pmid:24456004 |
| Magrone T et al. | Human use of Leucoselect® Phytosome® with special reference to inflammatory-allergic pathologies in frail elderly patients. | 2014 | Curr. Pharm. Des. | pmid:23701566 |
| Cui Y et al. | Protective effects of polyphenols-enriched extract from Huangshan Maofeng green tea against CCl4-induced liver injury in mice. | 2014 | Chem. Biol. Interact. | pmid:24973642 |
| Lee EJ et al. | Hyaluronic acid/poly(lactic-co-glycolic acid) core/shell fiber meshes loaded with epigallocatechin-3-O-gallate as skin tissue engineering scaffolds. | 2014 | J Nanosci Nanotechnol | pmid:25958546 |
| Zhao C et al. | The galloyl catechins contributing to main antioxidant capacity of tea made from Camellia sinensis in China. | 2014 | ScientificWorldJournal | pmid:25243234 |
| Kang SN et al. | In vitro anti-osteoporosis properties of diverse Korean Drynariae rhizoma phenolic extracts. | 2014 | Nutrients | pmid:24763116 |
| Xie H et al. | Catechins and procyanidins of Ginkgo biloba show potent activities towards the inhibition of β-amyloid peptide aggregation and destabilization of preformed fibrils. | 2014 | Molecules | pmid:24759072 |
| Butnariu M | Detection of the polyphenolic components in Ribes nigrum L. | 2014 | Ann Agric Environ Med | pmid:24742033 |
| Jang JH et al. | Analysis of green tea compounds and their stability in dentifrices of different pH levels. | 2014 | Chem. Pharm. Bull. | pmid:24695342 |
| van Duynhoven J et al. | Rapid and sustained systemic circulation of conjugated gut microbial catabolites after single-dose black tea extract consumption. | 2014 | J. Proteome Res. | pmid:24673575 |
| Snoussi C et al. | Green tea decoction improves glucose tolerance and reduces weight gain of rats fed normal and high-fat diet. | 2014 | J. Nutr. Biochem. | pmid:24656388 |
| Bindon KA and Smith PA | Comparison of the affinity and selectivity of insoluble fibres and commercial proteins for wine proanthocyanidins. | 2013 | Food Chem | pmid:23122145 |
| Cryan LM et al. | 1,2,3,4,6-Penta-O-galloyl-β-D-glucopyranose inhibits angiogenesis via inhibition of capillary morphogenesis gene 2. | 2013 | J. Med. Chem. | pmid:23394144 |