(-)-Epigallocatechin is a lipid of Polyketides (PK) class. The involved functions are known as Protective Agents, inhibitors, Process, Drug Kinetics and Fermentation. (-)-epigallocatechin often locates in Hepatic, Blood, Membrane, Back and apical membrane. The associated genes with (-)-Epigallocatechin are ADRBK1 gene and FASTK Gene. The related lipids are 1,2-dilinolenoyl-3-(4-aminobutyryl)propane-1,2,3-triol. The related experimental models are Rodent Model and Transgenic Model.
To understand associated biological information of (-)-Epigallocatechin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
There are no associated biomedical information in the current reference collection.
We collected disease MeSH terms mapped to the references associated with (-)-Epigallocatechin
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
| Mammary Neoplasms, Experimental | D008325 | 67 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Liver Diseases | D008107 | 31 associated lipids |
| Glioblastoma | D005909 | 27 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
| Gene | Cross reference | Weighted score | Related literatures |
|---|
Rodent Model are used in the study 'Dietary (-)-epicatechin as a potent inhibitor of βγ-secretase amyloid precursor protein processing.' (Cox CJ et al., 2015) and Rodent Model are used in the study 'Effects of dosing condition on the oral bioavailability of green tea catechins after single-dose administration of Polyphenon E in healthy individuals.' (Chow HH et al., 2005).
Transgenic Model are used in the study 'Dietary (-)-epicatechin as a potent inhibitor of βγ-secretase amyloid precursor protein processing.' (Cox CJ et al., 2015).
| Model | Cross reference | Weighted score | Related literatures |
|---|
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Bindon KA and Smith PA | Comparison of the affinity and selectivity of insoluble fibres and commercial proteins for wine proanthocyanidins. | 2013 | Food Chem | pmid:23122145 |
| Egert S et al. | Simultaneous ingestion of dietary proteins reduces the bioavailability of galloylated catechins from green tea in humans. | 2013 | Eur J Nutr | pmid:22366739 |
| Teixeira N et al. | Structural features of copigmentation of oenin with different polyphenol copigments. | 2013 | J. Agric. Food Chem. | pmid:23829187 |
| Tsujita T et al. | α-Amylase inhibitory activity from nut seed skin polyphenols. 1. Purification and characterization of almond seed skin polyphenols. | 2013 | J. Agric. Food Chem. | pmid:23614772 |
| Zhang ZZ et al. | Transcriptional activation of flavan-3-ols biosynthesis in grape berries by UV irradiation depending on developmental stage. | 2013 | Plant Sci. | pmid:23683931 |
| Trnková L et al. | Green tea catechins can bind and modify ERp57/PDIA3 activity. | 2013 | Biochim. Biophys. Acta | pmid:23671928 |
| Ghosh S et al. | (-)-Epicatechin gallate prevents alkali-salt mediated fibrillogenesis of hen egg white lysozyme. | 2013 | Int. J. Biol. Macromol. | pmid:23219698 |
| Park JS et al. | EGCG inhibits recepteur d'origine nantais expression by suppressing Egr-1 in gastric cancer cells. | 2013 | Int. J. Oncol. | pmid:23337910 |
| Lin G et al. | Enantioselective total syntheses of (+)-gallocatechin, (-)-epigallocatechin, and 8-C-ascorbyl-(-)-epigallocatechin. | 2013 | Chem Asian J | pmid:23362126 |
| Krych J and Gebicka L | Catalase is inhibited by flavonoids. | 2013 | Int. J. Biol. Macromol. | pmid:23567286 |
| Chung JH et al. | Green tea formulations with vitamin C and xylitol on enhanced intestinal transport of green tea catechins. | 2013 | J. Food Sci. | pmid:23551173 |
| Hong YH et al. | Tannase-converted green tea catechins and their anti-wrinkle activity in humans. | 2013 | J Cosmet Dermatol | pmid:23725307 |
| Roy S et al. | Combination therapy of dexamethasone with epigallocatechin enhances tibiotarsal bone articulation and modulates oxidative status correlates with cartilage cytokines expression in the early phase of experimental arthritis. | 2013 | Eur. J. Pharmacol. | pmid:23183110 |
| Zhao L et al. | Green tea catechins quench the fluorescence of bacteria-conjugated Alexa fluor dyes. | 2013 | Inflamm Allergy Drug Targets | pmid:24011199 |
| Yu SY et al. | Phenolic composition, antioxidant activity and anti-adipogenic effect of hot water extract from safflower (Carthamus tinctorius L.) seed. | 2013 | Nutrients | pmid:24288028 |
| Lee LS et al. | Optimization of ultrasonic extraction of phenolic antioxidants from green tea using response surface methodology. | 2013 | Molecules | pmid:24184822 |
| Chen XQ et al. | Blood anticoagulation and antiplatelet activity of green tea (-)-epigallocatechin (EGC) in mice. | 2013 | Food Funct | pmid:24056410 |
| Koga K et al. | Proanthocyanidin oligomers isolated from Salacia reticulata leaves potently inhibit pancreatic lipase activity. | 2013 | J. Food Sci. | pmid:23278351 |
| Cryan LM et al. | 1,2,3,4,6-Penta-O-galloyl-β-D-glucopyranose inhibits angiogenesis via inhibition of capillary morphogenesis gene 2. | 2013 | J. Med. Chem. | pmid:23394144 |
| Allen CL et al. | Augmented dried versus cryopreserved amniotic membrane as an ocular surface dressing. | 2013 | PLoS ONE | pmid:24205233 |