(-)-Epigallocatechin is a lipid of Polyketides (PK) class. The involved functions are known as Protective Agents, inhibitors, Process, Drug Kinetics and Fermentation. (-)-epigallocatechin often locates in Hepatic, Blood, Membrane, Back and apical membrane. The associated genes with (-)-Epigallocatechin are ADRBK1 gene and FASTK Gene. The related lipids are 1,2-dilinolenoyl-3-(4-aminobutyryl)propane-1,2,3-triol. The related experimental models are Rodent Model and Transgenic Model.
To understand associated biological information of (-)-Epigallocatechin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
There are no associated biomedical information in the current reference collection.
We collected disease MeSH terms mapped to the references associated with (-)-Epigallocatechin
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
| Mammary Neoplasms, Experimental | D008325 | 67 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Liver Diseases | D008107 | 31 associated lipids |
| Glioblastoma | D005909 | 27 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
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| Function | Cross reference | Weighted score | Related literatures |
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| Lipid concept | Cross reference | Weighted score | Related literatures |
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| Gene | Cross reference | Weighted score | Related literatures |
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Rodent Model are used in the study 'Dietary (-)-epicatechin as a potent inhibitor of βγ-secretase amyloid precursor protein processing.' (Cox CJ et al., 2015) and Rodent Model are used in the study 'Effects of dosing condition on the oral bioavailability of green tea catechins after single-dose administration of Polyphenon E in healthy individuals.' (Chow HH et al., 2005).
Transgenic Model are used in the study 'Dietary (-)-epicatechin as a potent inhibitor of βγ-secretase amyloid precursor protein processing.' (Cox CJ et al., 2015).
| Model | Cross reference | Weighted score | Related literatures |
|---|
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Bindon KA and Smith PA | Comparison of the affinity and selectivity of insoluble fibres and commercial proteins for wine proanthocyanidins. | 2013 | Food Chem | pmid:23122145 |
| Ghosh S et al. | (-)-Epicatechin gallate prevents alkali-salt mediated fibrillogenesis of hen egg white lysozyme. | 2013 | Int. J. Biol. Macromol. | pmid:23219698 |
| Roy S et al. | Combination therapy of dexamethasone with epigallocatechin enhances tibiotarsal bone articulation and modulates oxidative status correlates with cartilage cytokines expression in the early phase of experimental arthritis. | 2013 | Eur. J. Pharmacol. | pmid:23183110 |
| Koga K et al. | Proanthocyanidin oligomers isolated from Salacia reticulata leaves potently inhibit pancreatic lipase activity. | 2013 | J. Food Sci. | pmid:23278351 |
| Yano T et al. | Unified approach to catechin hetero-oligomers: first total synthesis of trimer EZ-EG-CA isolated from Ziziphus jujuba. | 2012 | Org. Biomol. Chem. | pmid:22930202 |
| Arimboor R and Arumughan C | Effect of polymerization on antioxidant and xanthine oxidase inhibitory potential of sea buckthorn (H. rhamnoides) proanthocyanidins. | 2012 | J. Food Sci. | pmid:22938149 |
| Zhou YB et al. | Polyphenol content of plasma and litter after the oral administration of green tea and tea polyphenols in chickens. | 2012 | J. Agric. Food Chem. | pmid:22224899 |
| Wang H et al. | Profiles and α-amylase inhibition activity of proanthocyanidins in unripe Manilkara zapota (chiku). | 2012 | J. Agric. Food Chem. | pmid:22394060 |
| Li D et al. | Development of an isocratic HPLC method for catechin quantification and its application to formulation studies. | 2012 | Fitoterapia | pmid:22735602 |
| Delcambre A and Saucier C | Identification of new flavan-3-ol monoglycosides by UHPLC-ESI-Q-TOF in grapes and wine. | 2012 | J Mass Spectrom | pmid:22707165 |
| Bustos I et al. | Effect of flavan-3-ols on the adhesion of potential probiotic lactobacilli to intestinal cells. | 2012 | J. Agric. Food Chem. | pmid:22889010 |
| de-Faria FM et al. | Antioxidant action of mangrove polyphenols against gastric damage induced by absolute ethanol and ischemia-reperfusion in the rat. | 2012 | ScientificWorldJournal | pmid:22654592 |
| Park CH et al. | Protective Effects of Corni Fructus against Advanced Glycation Endproducts and Radical Scavenging. | 2012 | Evid Based Complement Alternat Med | pmid:22649473 |
| Umar KM et al. | Engineering the production of major catechins by Escherichia coli carrying metabolite genes of Camellia sinensis. | 2012 | ScientificWorldJournal | pmid:22645428 |
| Jimenez-Del-Rio M and Velez-Pardo C | The bad, the good, and the ugly about oxidative stress. | 2012 | Oxid Med Cell Longev | pmid:22619696 |
| Margina D et al. | Quercetin and epigallocatechin gallate induce in vitro a dose-dependent stiffening and hyperpolarizing effect on the cell membrane of human mononuclear blood cells. | 2012 | Int J Mol Sci | pmid:22606013 |
| Koppula S et al. | Reactive oxygen species and inhibitors of inflammatory enzymes, NADPH oxidase, and iNOS in experimental models of Parkinson's disease. | 2012 | Mediators Inflamm. | pmid:22577256 |
| Berindan-Neagoe I et al. | Early apoptosis signals induced by a low dose of epigallocatechin 3-gallate interfere with apoptotic and cell death pathways. | 2012 | J Nanosci Nanotechnol | pmid:22755028 |
| Cohen SD et al. | Impact of diurnal temperature variation on grape berry development, proanthocyanidin accumulation, and the expression of flavonoid pathway genes. | 2012 | J. Exp. Bot. | pmid:22268158 |
| Wen KC et al. | Ixora parviflora Protects against UVB-Induced Photoaging by Inhibiting the Expression of MMPs, MAP Kinases, and COX-2 and by Promoting Type I Procollagen Synthesis. | 2012 | Evid Based Complement Alternat Med | pmid:22203872 |