(-)-Epigallocatechin is a lipid of Polyketides (PK) class. The involved functions are known as Protective Agents, inhibitors, Process, Drug Kinetics and Fermentation. (-)-epigallocatechin often locates in Hepatic, Blood, Membrane, Back and apical membrane. The associated genes with (-)-Epigallocatechin are ADRBK1 gene and FASTK Gene. The related lipids are 1,2-dilinolenoyl-3-(4-aminobutyryl)propane-1,2,3-triol. The related experimental models are Rodent Model and Transgenic Model.
To understand associated biological information of (-)-Epigallocatechin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
There are no associated biomedical information in the current reference collection.
We collected disease MeSH terms mapped to the references associated with (-)-Epigallocatechin
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
| Mammary Neoplasms, Experimental | D008325 | 67 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Liver Diseases | D008107 | 31 associated lipids |
| Glioblastoma | D005909 | 27 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
| Gene | Cross reference | Weighted score | Related literatures |
|---|
Rodent Model are used in the study 'Dietary (-)-epicatechin as a potent inhibitor of βγ-secretase amyloid precursor protein processing.' (Cox CJ et al., 2015) and Rodent Model are used in the study 'Effects of dosing condition on the oral bioavailability of green tea catechins after single-dose administration of Polyphenon E in healthy individuals.' (Chow HH et al., 2005).
Transgenic Model are used in the study 'Dietary (-)-epicatechin as a potent inhibitor of βγ-secretase amyloid precursor protein processing.' (Cox CJ et al., 2015).
| Model | Cross reference | Weighted score | Related literatures |
|---|
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Xiao JS et al. | Characterization of oligomeric procyanidins and identification of quercetin glucuronide from lotus ( Nelumbo nucifera Gaertn.) seedpod. | 2012 | J. Agric. Food Chem. | pmid:22369273 |
| Lee YH et al. | EGCG suppresses prostate cancer cell growth modulating acetylation of androgen receptor by anti-histone acetyltransferase activity. | 2012 | Int. J. Mol. Med. | pmid:22505206 |
| Roy S et al. | A novel combination of methotrexate and epigallocatechin attenuates the overexpression of pro-inflammatory cartilage cytokines and modulates antioxidant status in adjuvant arthritic rats. | 2012 | Inflammation | pmid:22453361 |
| Sasaki T et al. | Green tea catechins increase the force of contraction in isolated guinea pig atrial muscle preparations by increasing the amplitude of intracellular Ca2+ concentration. | 2012 | J. Vet. Med. Sci. | pmid:22864409 |
| Wink M et al. | Secondary Metabolites from Plants Inhibiting ABC Transporters and Reversing Resistance of Cancer Cells and Microbes to Cytotoxic and Antimicrobial Agents. | 2012 | Front Microbiol | pmid:22536197 |
| Jaiswal R et al. | Identification and characterization of proanthocyanidins of 16 members of the Rhododendron genus (Ericaceae) by tandem LC-MS. | 2012 | J Mass Spectrom | pmid:22689627 |
| Theisen LL and Muller CP | EPs® 7630 (Umckaloabo®), an extract from Pelargonium sidoides roots, exerts anti-influenza virus activity in vitro and in vivo. | 2012 | Antiviral Res. | pmid:22475498 |
| Zhu L et al. | Phenolic contents and compositions in skins of red wine grape cultivars among various genetic backgrounds and originations. | 2012 | Int J Mol Sci | pmid:22489164 |
| Apak R et al. | Selective determination of catechin among phenolic antioxidants with the use of a novel optical fiber reflectance sensor based on indophenol dye formation on nano-sized TiOâ‚‚. | 2012 | J. Agric. Food Chem. | pmid:22339278 |
| Maeda-Yamamoto M et al. | Epicatechin-3-O-(3″-O-methyl)-gallate content in various tea cultivars (Camellia sinensis L.) and its in vitro inhibitory effect on histamine release. | 2012 | J. Agric. Food Chem. | pmid:22339247 |
| Huang R et al. | NMR characterization of monomeric and oligomeric conformations of human calcitonin and its interaction with EGCG. | 2012 | J. Mol. Biol. | pmid:22200484 |
| Miller RJ et al. | A preliminary investigation of the impact of catechol-O-methyltransferase genotype on the absorption and metabolism of green tea catechins. | 2012 | Eur J Nutr | pmid:21445620 |
| Grabber JH et al. | Identifying new lignin bioengineering targets: impact of epicatechin, quercetin glycoside, and gallate derivatives on the lignification and fermentation of maize cell walls. | 2012 | J. Agric. Food Chem. | pmid:22475000 |
| Joo SY et al. | Epigallocatechin-3-gallate Inhibits LPS-Induced NF-κB and MAPK Signaling Pathways in Bone Marrow-Derived Macrophages. | 2012 | Gut Liver | pmid:22570747 |
| Sabry M and Al-Hendy A | Innovative oral treatments of uterine leiomyoma. | 2012 | Obstet Gynecol Int | pmid:22518167 |
| Gates PJ and Lopes NP | Characterisation of flavonoid aglycones by negative ion chip-based nanospray tandem mass spectrometry. | 2012 | Int J Anal Chem | pmid:22505914 |
| Chen YY et al. | Ethanol extracts of fruiting bodies of Antrodia cinnamomea suppress CL1-5 human lung adenocarcinoma cells migration by inhibiting matrix metalloproteinase-2/9 through ERK, JNK, p38, and PI3K/Akt signaling pathways. | 2012 | Evid Based Complement Alternat Med | pmid:22454661 |
| Sabhapondit S et al. | Diversity of catechin in northeast Indian tea cultivars. | 2012 | ScientificWorldJournal | pmid:22448135 |
| Saldanha SN and Tollefsbol TO | The role of nutraceuticals in chemoprevention and chemotherapy and their clinical outcomes. | 2012 | J Oncol | pmid:22187555 |
| Kang MY et al. | Preventive effects of green tea (Camellia sinensis var. assamica) on diabetic nephropathy. | 2012 | Yonsei Med. J. | pmid:22187244 |