(-)-Epigallocatechin is a lipid of Polyketides (PK) class. The involved functions are known as Protective Agents, inhibitors, Process, Drug Kinetics and Fermentation. (-)-epigallocatechin often locates in Hepatic, Blood, Membrane, Back and apical membrane. The associated genes with (-)-Epigallocatechin are ADRBK1 gene and FASTK Gene. The related lipids are 1,2-dilinolenoyl-3-(4-aminobutyryl)propane-1,2,3-triol. The related experimental models are Rodent Model and Transgenic Model.
To understand associated biological information of (-)-Epigallocatechin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
There are no associated biomedical information in the current reference collection.
We collected disease MeSH terms mapped to the references associated with (-)-Epigallocatechin
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
| Mammary Neoplasms, Experimental | D008325 | 67 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Liver Diseases | D008107 | 31 associated lipids |
| Glioblastoma | D005909 | 27 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
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| Function | Cross reference | Weighted score | Related literatures |
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| Lipid concept | Cross reference | Weighted score | Related literatures |
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| Gene | Cross reference | Weighted score | Related literatures |
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Rodent Model are used in the study 'Dietary (-)-epicatechin as a potent inhibitor of βγ-secretase amyloid precursor protein processing.' (Cox CJ et al., 2015) and Rodent Model are used in the study 'Effects of dosing condition on the oral bioavailability of green tea catechins after single-dose administration of Polyphenon E in healthy individuals.' (Chow HH et al., 2005).
Transgenic Model are used in the study 'Dietary (-)-epicatechin as a potent inhibitor of βγ-secretase amyloid precursor protein processing.' (Cox CJ et al., 2015).
| Model | Cross reference | Weighted score | Related literatures |
|---|
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Kumamoto M et al. | Effects of pH and metal ions on antioxidative activities of catechins. | 2001 | Biosci. Biotechnol. Biochem. | pmid:11272815 |
| Hayakawa F et al. | Prooxidative activities of tea catechins in the presence of Cu2+. | 2004 | Biosci. Biotechnol. Biochem. | pmid:15388955 |
| Suzuki Y et al. | Dose-dependent suppression of tea catechins with a galloyl moiety on postprandial hypertriglyceridemia in rats. | 2005 | Biosci. Biotechnol. Biochem. | pmid:16041132 |
| Hayashi N et al. | Reduction of catechin astringency by the complexation of gallate-type catechins with pectin. | 2005 | Biosci. Biotechnol. Biochem. | pmid:16041135 |
| Mun'im A et al. | Antioxidative compounds from Crotalaria sessiliflora. | 2003 | Biosci. Biotechnol. Biochem. | pmid:12729010 |
| Cheruiyot EK et al. | Shoot epicatechin and epigallocatechin contents respond to water stress in tea [Camellia sinensis (L.) O. Kuntze]. | 2008 | Biosci. Biotechnol. Biochem. | pmid:18460799 |
| Sakanaka S et al. | Inhibitory effects of green tea polyphenols on growth and cellular adherence of an oral bacterium, Porphyromonas gingivalis. | 1996 | Biosci. Biotechnol. Biochem. | pmid:8704303 |
| Nakagawa K et al. | Dose-dependent incorporation of tea catechins, (-)-epigallocatechin-3-gallate and (-)-epigallocatechin, into human plasma. | 1997 | Biosci. Biotechnol. Biochem. | pmid:9438978 |
| Nomizu K et al. | Antioxidants from steamed used tea leaves and their reaction behavior. | 2008 | Biosci. Biotechnol. Biochem. | pmid:18603807 |
| Kakuda T et al. | Effects of tea (Camellia sinensis) chemical compounds on ethanol metabolism in ICR mice. | 1996 | Biosci. Biotechnol. Biochem. | pmid:8987593 |
| Furuyashiki T et al. | Tea catechin suppresses adipocyte differentiation accompanied by down-regulation of PPARgamma2 and C/EBPalpha in 3T3-L1 cells. | 2004 | Biosci. Biotechnol. Biochem. | pmid:15564676 |
| Kajiya K et al. | Effects of external factors on the interaction of tea catechins with lipid bilayers. | 2002 | Biosci. Biotechnol. Biochem. | pmid:12506968 |
| Yoshioka H et al. | Spin-trapping study on the hydroxyl radical formed from a tea catechin-Cu(II) system. | 2001 | Biosci. Biotechnol. Biochem. | pmid:11577706 |
| Kida K et al. | Deodorizing effects of tea catechins on amines and ammonia. | 2002 | Biosci. Biotechnol. Biochem. | pmid:11999411 |
| Murakami C et al. | Effect of tea catechins on cellular lipid peroxidation and cytotoxicity in HepG2 cells. | 2002 | Biosci. Biotechnol. Biochem. | pmid:12224642 |
| Hashimoto T et al. | Interaction of tea catechins with lipid bilayers investigated with liposome systems. | 1999 | Biosci. Biotechnol. Biochem. | pmid:10664864 |
| Monobe M et al. | Effect on the epigallocatechin gallate/epigallocatechin ratio in a green tea (Camellia sinensis L.) extract of different extraction temperatures and its effect on IgA production in mice. | 2010 | Biosci. Biotechnol. Biochem. | pmid:21150115 |
| Ishii T et al. | Human serum albumin as an antioxidant in the oxidation of (-)-epigallocatechin gallate: participation of reversible covalent binding for interaction and stabilization. | 2011 | Biosci. Biotechnol. Biochem. | pmid:21228463 |
| Monobe M et al. | Increased plasma concentration of epigallocatechin in mice after orally administering a green tea (Camellia sinensis L.) extract supplemented by steamed rice. | 2011 | Biosci. Biotechnol. Biochem. | pmid:21228465 |
| Jiang Y et al. | Immunoregulatory and anti-HIV-1 enzyme activities of antioxidant components from lotus (Nelumbo nucifera Gaertn.) rhizome. | 2011 | Biosci. Rep. | pmid:21114474 |