(-)-Epigallocatechin is a lipid of Polyketides (PK) class. The involved functions are known as Protective Agents, inhibitors, Process, Drug Kinetics and Fermentation. (-)-epigallocatechin often locates in Hepatic, Blood, Membrane, Back and apical membrane. The associated genes with (-)-Epigallocatechin are ADRBK1 gene and FASTK Gene. The related lipids are 1,2-dilinolenoyl-3-(4-aminobutyryl)propane-1,2,3-triol. The related experimental models are Rodent Model and Transgenic Model.
To understand associated biological information of (-)-Epigallocatechin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
There are no associated biomedical information in the current reference collection.
We collected disease MeSH terms mapped to the references associated with (-)-Epigallocatechin
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
| Mammary Neoplasms, Experimental | D008325 | 67 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Liver Diseases | D008107 | 31 associated lipids |
| Glioblastoma | D005909 | 27 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
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| Function | Cross reference | Weighted score | Related literatures |
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| Lipid concept | Cross reference | Weighted score | Related literatures |
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| Gene | Cross reference | Weighted score | Related literatures |
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Rodent Model are used in the study 'Dietary (-)-epicatechin as a potent inhibitor of βγ-secretase amyloid precursor protein processing.' (Cox CJ et al., 2015) and Rodent Model are used in the study 'Effects of dosing condition on the oral bioavailability of green tea catechins after single-dose administration of Polyphenon E in healthy individuals.' (Chow HH et al., 2005).
Transgenic Model are used in the study 'Dietary (-)-epicatechin as a potent inhibitor of βγ-secretase amyloid precursor protein processing.' (Cox CJ et al., 2015).
| Model | Cross reference | Weighted score | Related literatures |
|---|
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Dauer A et al. | Polymeric proanthocyanidins from the bark of Hamamelis virginiana. | 2003 | Planta Med. | pmid:12567291 |
| Lin YS et al. | Determination of tea polyphenols and caffeine in tea flowers (Camellia sinensis) and their hydroxyl radical scavenging and nitric oxide suppressing effects. | 2003 | J. Agric. Food Chem. | pmid:12568558 |
| Behrens A et al. | MALDI-TOF mass spectrometry and PSD fragmentation as means for the analysis of condensed tannins in plant leaves and needles. | 2003 | Phytochemistry | pmid:12591272 |
| Lu H et al. | Glucuronides of tea catechins: enzymology of biosynthesis and biological activities. | 2003 | Drug Metab. Dispos. | pmid:12642472 |
| Lin YS et al. | Factors affecting the levels of tea polyphenols and caffeine in tea leaves. | 2003 | J. Agric. Food Chem. | pmid:12643643 |
| Lu H et al. | Enzymology of methylation of tea catechins and inhibition of catechol-O-methyltransferase by (-)-epigallocatechin gallate. | 2003 | Drug Metab. Dispos. | pmid:12695345 |
| Yang LL et al. | Antitumor principle constituents of Myrica rubra Var. acuminata. | 2003 | J. Agric. Food Chem. | pmid:12720379 |
| Malik A et al. | DNA degradation by water extract of green tea in the presence of copper ions: implications for anticancer properties. | 2003 | Phytother Res | pmid:12722140 |
| Levine L | Does the release of arachidonic acid from cells play a role in cancer chemoprevention? | 2003 | FASEB J. | pmid:12724337 |
| Mun'im A et al. | Antioxidative compounds from Crotalaria sessiliflora. | 2003 | Biosci. Biotechnol. Biochem. | pmid:12729010 |
| Weber JM et al. | Inhibition of adenovirus infection and adenain by green tea catechins. | 2003 | Antiviral Res. | pmid:12742577 |
| Hagerman AE et al. | Radical chemistry of epigallocatechin gallate and its relevance to protein damage. | 2003 | Arch. Biochem. Biophys. | pmid:12745262 |
| Pomponio R et al. | Microemulsion electrokinetic chromatography for the analysis of green tea catechins: effect of the cosurfactant on the separation selectivity. | 2003 | Electrophoresis | pmid:12761797 |
| Roginsky V | Chain-breaking antioxidant activity of natural polyphenols as determined during the chain oxidation of methyl linoleate in Triton X-100 micelles. | 2003 | Arch. Biochem. Biophys. | pmid:12781778 |
| Zhang N et al. | An inducible nitric oxide synthase-luciferase reporter system for in vivo testing of anti-inflammatory compounds in transgenic mice. | 2003 | J. Immunol. | pmid:12794164 |
| Taylor AW et al. | Hop (Humulus lupulus L.) proanthocyanidins characterized by mass spectrometry, acid catalysis, and gel permeation chromatography. | 2003 | J. Agric. Food Chem. | pmid:12822954 |
| Lill G et al. | Complex effects of different green tea catechins on human platelets. | 2003 | FEBS Lett. | pmid:12832052 |
| Cabrera C et al. | Determination of tea components with antioxidant activity. | 2003 | J. Agric. Food Chem. | pmid:12848521 |
| Palermo CM et al. | Identification of potential aryl hydrocarbon receptor antagonists in green tea. | 2003 | Chem. Res. Toxicol. | pmid:12870889 |
| Mizooku Y et al. | Analysis of oxidized epigallocatechin gallate by liquid chromatography/mass spectrometry. | 2003 | Rapid Commun. Mass Spectrom. | pmid:12876693 |