9-HODE

9-hode is a lipid of Fatty Acyls (FA) class. 9-hode is associated with abnormalities such as Atherosclerosis, Chronic disease and Rheumatoid Arthritis. The involved functions are known as Oxidation, Transcriptional Activation, Esthesia, Signal Transduction and Process. 9-hode often locates in viral nucleocapsid location, Blood, Body tissue, Protoplasm and Lysosomal. The associated genes with 9-HODE are CD1A gene, CD276 Antigen, CD14 gene, IMPACT gene and GPR132 gene. The related lipids are Fatty Acids, 9-hydroxy-10,12-octadecadienoic acid, Nonesterified Fatty Acids, octadecadienoic acid and Total cholesterol.

Cross Reference

Introduction

To understand associated biological information of 9-HODE, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 9-HODE?

9-HODE is suspected in Atherosclerosis, Chronic disease, Rheumatoid Arthritis and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 9-HODE

MeSH term MeSH ID Detail
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Body Weight D001835 333 associated lipids
Familial Mediterranean Fever D010505 12 associated lipids
Total 3

PubChem Associated disorders and diseases

What pathways are associated with 9-HODE

Lipid pathways are not clear in current pathway databases. We organized associated pathways with 9-HODE through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
Loading... please refresh the page if content is not showing up.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 9-HODE?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with 9-HODE?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 9-HODE?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with 9-HODE?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 9-HODE?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 9-HODE

Download all related citations
Per page 10 20 50 100 | Total 107
Authors Title Published Journal PubMed Link
pmid:
Bürger F et al. Constitutive expression of 8-lipoxygenase in papillomas and clastogenic effects of lipoxygenase-derived arachidonic acid metabolites in keratinocytes. 1999 Mol. Carcinog. pmid:10078938
Inouye M et al. Formation of 9-hydroxy linoleic acid as a product of phospholipid peroxidation in diabetic erythrocyte membranes. 1999 Biochim. Biophys. Acta pmid:10320803
Truitt A et al. Antiplatelet effects of conjugated linoleic acid isomers. 1999 Biochim. Biophys. Acta pmid:10320806
Garcia-Cruset S et al. Oxysterols in cap and core of human advanced atherosclerotic lesions. 1999 Free Radic. Res. pmid:10342328
Sarraf P et al. Loss-of-function mutations in PPAR gamma associated with human colon cancer. 1999 Mol. Cell pmid:10394368
Chen NG et al. PPARgamma agonists enhance human vascular endothelial adhesiveness by increasing ICAM-1 expression. 1999 Biochem. Biophys. Res. Commun. pmid:10512746
Jang MK et al. Regulation of ferritin light chain gene expression by oxidized low-density lipoproteins in human monocytic THP-1 cells. 1999 Biochem. Biophys. Res. Commun. pmid:10558912
Bürger F et al. Positional- and stereo-selectivity of fatty acid oxygenation catalysed by mouse (12S)-lipoxygenase isoenzymes. 2000 Biochem. J. pmid:10816426
Han KH et al. Oxidized LDL reduces monocyte CCR2 expression through pathways involving peroxisome proliferator-activated receptor gamma. 2000 J. Clin. Invest. pmid:10995790