MeSH term | MeSH ID | Detail |
---|---|---|
Diabetes Mellitus, Type 2 | D003924 | 87 associated lipids |
Body Weight | D001835 | 333 associated lipids |
Familial Mediterranean Fever | D010505 | 12 associated lipids |
9-hode is a lipid of Fatty Acyls (FA) class. 9-hode is associated with abnormalities such as Atherosclerosis, Chronic disease and Rheumatoid Arthritis. The involved functions are known as Oxidation, Transcriptional Activation, Esthesia, Signal Transduction and Process. 9-hode often locates in viral nucleocapsid location, Blood, Body tissue, Protoplasm and Lysosomal. The associated genes with 9-HODE are CD1A gene, CD276 Antigen, CD14 gene, IMPACT gene and GPR132 gene. The related lipids are Fatty Acids, 9-hydroxy-10,12-octadecadienoic acid, Nonesterified Fatty Acids, octadecadienoic acid and Total cholesterol.
To understand associated biological information of 9-HODE, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
9-HODE is suspected in Atherosclerosis, Chronic disease, Rheumatoid Arthritis and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with 9-HODE
MeSH term | MeSH ID | Detail |
---|---|---|
Diabetes Mellitus, Type 2 | D003924 | 87 associated lipids |
Body Weight | D001835 | 333 associated lipids |
Familial Mediterranean Fever | D010505 | 12 associated lipids |
Lipid pathways are not clear in current pathway databases. We organized associated pathways with 9-HODE through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Pathway name | Related literatures |
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Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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pmid:25330944 | ||||
pmid:28923202 | ||||
pmid:27018002 | ||||
pmid:25899850 | ||||
pmid:25381799 | ||||
pmid:28886714 | ||||
pmid:9679335 | ||||
pmid: | ||||
Hamberg M and Samuelsson B | Stereochemistry in the formation of 9-hydroxy-10,12-octadecadienoic acid and 13-hydroxy-9,11-octadecadienoic acid from linoleic acid by fatty acid cyclooxygenase. | 1980 | Biochim. Biophys. Acta | pmid:6768399 |
Claeys M et al. | Characterization of monohydroxylated lipoxygenase metabolites of arachidonic and linoleic acid in rabbit peritoneal tissue. | 1982 | Biochim. Biophys. Acta | pmid:6814493 |