MeSH term | MeSH ID | Detail |
---|---|---|
Diabetes Mellitus, Type 2 | D003924 | 87 associated lipids |
Body Weight | D001835 | 333 associated lipids |
Familial Mediterranean Fever | D010505 | 12 associated lipids |
9-hode is a lipid of Fatty Acyls (FA) class. 9-hode is associated with abnormalities such as Atherosclerosis, Chronic disease and Rheumatoid Arthritis. The involved functions are known as Oxidation, Transcriptional Activation, Esthesia, Signal Transduction and Process. 9-hode often locates in viral nucleocapsid location, Blood, Body tissue, Protoplasm and Lysosomal. The associated genes with 9-HODE are CD1A gene, CD276 Antigen, CD14 gene, IMPACT gene and GPR132 gene. The related lipids are Fatty Acids, 9-hydroxy-10,12-octadecadienoic acid, Nonesterified Fatty Acids, octadecadienoic acid and Total cholesterol.
To understand associated biological information of 9-HODE, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
9-HODE is suspected in Atherosclerosis, Chronic disease, Rheumatoid Arthritis and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with 9-HODE
MeSH term | MeSH ID | Detail |
---|---|---|
Diabetes Mellitus, Type 2 | D003924 | 87 associated lipids |
Body Weight | D001835 | 333 associated lipids |
Familial Mediterranean Fever | D010505 | 12 associated lipids |
Lipid pathways are not clear in current pathway databases. We organized associated pathways with 9-HODE through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Pathway name | Related literatures |
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Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Camp RD and Fincham NJ | Inhibition of ionophore-stimulated leukotriene B4 production in human leucocytes by monohydroxy fatty acids. | 1985 | Br. J. Pharmacol. | pmid:2994785 |
Aisen PS et al. | Circulating hydroxy fatty acids in familial Mediterranean fever. | 1985 | Proc. Natl. Acad. Sci. U.S.A. | pmid:3919389 |
Engels F et al. | Cyclooxygenase-catalyzed formation of 9-hydroxylinoleic acid by guinea pig alveolar macrophages under non-stimulated conditions. | 1986 | FEBS Lett. | pmid:3098580 |
Henry DY et al. | Isolation and characterization of 9-hydroxy-10-trans,12-cis-octadecadienoic acid, a novel regulator of platelet adenylate cyclase from Glechoma hederacea L. Labiatae. | 1987 | Eur. J. Biochem. | pmid:3691528 |
Nugteren DH and Kivits GA | Conversion of linoleic acid and arachidonic acid by skin epidermal lipoxygenases. | 1987 | Biochim. Biophys. Acta | pmid:3113487 |
Pankonin G et al. | Inhibition of cell migrations by the linoleic acid oxygenation product 9S-hydroxy 10E,12Z octadecadienoic acid (9-HODE). | 1988 | Biomed. Biochim. Acta | pmid:3151051 |
Kühn H et al. | Occurrence of free and esterified lipoxygenase products in leaves of Glechoma hederacea L. and other Labiatae. | 1989 | Eur. J. Biochem. | pmid:2598926 |
Daret D et al. | Synthesis of hydroxy fatty acids from linoleic acid by human blood platelets. | 1989 | Prostaglandins | pmid:2505334 |
Kaduce TL et al. | Formation of 9-hydroxyoctadecadienoic acid from linoleic acid in endothelial cells. | 1989 | J. Biol. Chem. | pmid:2496121 |
Engels F et al. | Modulatory activity of 9-hydroxy- and 9-hydroperoxy-octadecadienoic acid towards reactive oxygen species from guinea-pig pulmonary macrophages. | 1989 | Eur. J. Biochem. | pmid:2550227 |