alpha-artemisic acid

Alpha-artemisic acid is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 1126 references associated with alpha-artemisic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for alpha-artemisic acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with alpha-artemisic acid

MeSH term MeSH ID Detail
Adenocarcinoma D000230 166 associated lipids
Arteriosclerosis D001161 86 associated lipids
Carcinoma, Non-Small-Cell Lung D002289 72 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Hypertension D006973 115 associated lipids
Lung Neoplasms D008175 171 associated lipids
Familial Mediterranean Fever D010505 12 associated lipids
Adenomatous Polyposis Coli D011125 16 associated lipids
Thrombosis D013927 49 associated lipids
Colorectal Neoplasms D015179 10 associated lipids
Zellweger Syndrome D015211 39 associated lipids
Adenomatous Polyps D018256 4 associated lipids
Per page 10 20 | Total 13

NCBI Entrez Crosslinks

All references with alpha-artemisic acid

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Authors Title Published Journal PubMed Link
Baer AN et al. Stereospecificity of the hydroxyeicosatetraenoic and hydroxyoctadecadienoic acids produced by cultured bovine endothelial cells. 1991 Biochim. Biophys. Acta pmid:1892877
Baer AN et al. Stereospecificity of the products of the fatty acid oxygenases derived from psoriatic scales. 1991 J. Lipid Res. pmid:1906083
Henricks PA et al. 13-hydroxy-linoleic acid induces airway hyperreactivity to histamine in guinea-pigs. 1991 Eur. J. Pharmacol. pmid:1915571
Vane JR and Botting RM Endothelium--thromboresistance. 1991 Wien. Klin. Wochenschr. pmid:1926866
Chabane N et al. Human articular chondrocytes express 15-lipoxygenase-1 and -2: potential role in osteoarthritis. 2009 Arthritis Res. Ther. pmid:19296842
Baer AN et al. In vivo activation of an omega-6 oxygenase in human skin. 1991 Biochem. Biophys. Res. Commun. pmid:1930242
Kawakami Y et al. Antiproliferative activity of guava leaf extract via inhibition of prostaglandin endoperoxide H synthase isoforms. 2009 May-Jun Prostaglandins Leukot. Essent. Fatty Acids pmid:19457650
Wecksler AT et al. Mechanistic investigations of human reticulocyte 15- and platelet 12-lipoxygenases with arachidonic acid. 2009 Biochemistry pmid:19469483
Mabalirajan U et al. Effects of vitamin E on mitochondrial dysfunction and asthma features in an experimental allergic murine model. 2009 J. Appl. Physiol. pmid:19628725
Bastida E et al. Regulation of tumor cell adhesion by intracellular 13-HODE: 15-HETE ratio. 1990 Sep-Oct J Lipid Mediat pmid:1966807
Cimen I et al. 15-Lipoxygenase-1 expression suppresses the invasive properties of colorectal carcinoma cell lines HCT-116 and HT-29. 2009 Cancer Sci. pmid:19775287
Aznar-Salatti J et al. Platelet adhesion to exposed endothelial cell extracellular matrixes is influenced by the method of preparation. 1991 Mar-Apr Arterioscler. Thromb. pmid:1998660
Earles SM et al. Metabolism of oxidized linoleic acid: characterization of 13-hydroxyoctadecadienoic acid dehydrogenase activity from rat colonic tissue. 1991 Biochim. Biophys. Acta pmid:1998735
Blask DE et al. Circadian stage-dependent inhibition of human breast cancer metabolism and growth by the nocturnal melatonin signal: consequences of its disruption by light at night in rats and women. 2009 Integr Cancer Ther pmid:20042410
Li MY et al. Roles of peroxisome proliferator-activated receptor-alpha and -gamma in the development of non-small cell lung cancer. 2010 Am. J. Respir. Cell Mol. Biol. pmid:20081051
Bull AW et al. Metabolism of oxidized linoleic acid: distribution of activity for the enzymatic oxidation of 13-hydroxyoctadecadienoic acid to 13-oxooctadecadienoic acid in rat tissues. 1991 Prostaglandins pmid:2020745
Yuan H et al. 15-Lipoxygenases and its metabolites 15(S)-HETE and 13(S)-HODE in the development of non-small cell lung cancer. 2010 Thorax pmid:20388757
Liu W et al. Ex vivo oxidation in tissue and plasma assays of hydroxyoctadecadienoates: Z,E/E,E stereoisomer ratios. 2010 Chem. Res. Toxicol. pmid:20423158
Shureiqi I et al. Profiling lipoxygenase metabolism in specific steps of colorectal tumorigenesis. 2010 Cancer Prev Res (Phila) pmid:20570882
Imaizumi S et al. L-4F differentially alters plasma levels of oxidized fatty acids resulting in more anti-inflammatory HDL in mice. 2010 Drug Metab Lett pmid:20642447
Liu SH et al. Honokiol inhibits gastric tumourigenesis by activation of 15-lipoxygenase-1 and consequent inhibition of peroxisome proliferator-activated receptor-gamma and COX-2-dependent signals. 2010 Br. J. Pharmacol. pmid:20649594
Engels F et al. Modulation of guinea pig airway reactivity by the linoleic acid metabolite 13-hydroxy-octadecadienoic acid (13-HODE). 1990 Agents Actions Suppl. pmid:2080746
Miller CC and Ziboh VA Induction of epidermal hyperproliferation by topical n-3 polyunsaturated fatty acids on guinea pig skin linked to decreased levels of 13-hydroxyoctadecadienoic acid (13-hode). 1990 J. Invest. Dermatol. pmid:2106562
Ogawa E et al. Epidermal FABP (FABP5) regulates keratinocyte differentiation by 13(S)-HODE-mediated activation of the NF-κB signaling pathway. 2011 J. Invest. Dermatol. pmid:21068754
Schade UF et al. The role of 13-hydroxylinoleic acid in the activation of macrophages by lipopolysaccharide. 1990 Adv. Exp. Med. Biol. pmid:2109506
Chu J and Praticò D 5-lipoxygenase as an endogenous modulator of amyloid β formation in vivo. 2011 Ann. Neurol. pmid:21280074
Huang FC and Schwab W Cloning and characterization of a 9-lipoxygenase gene induced by pathogen attack from Nicotiana benthamiana for biotechnological application. 2011 BMC Biotechnol. pmid:21450085
Cimen I et al. 15-lipoxygenase-1 exerts its tumor suppressive role by inhibiting nuclear factor-kappa B via activation of PPAR gamma. 2011 J. Cell. Biochem. pmid:21544861
Haas TA et al. Cyclic AMP regulation of endothelial cell triacylglycerol turnover, 13-hydroxyoctadecadienoic acid (13-HODE) synthesis and endothelial cell thrombogenicity. 1990 Biochim. Biophys. Acta pmid:2155665
Buchanan MR et al. Fatty acid metabolism and cell/cell interactions. 1990 Agents Actions pmid:2183576
Aznar-Salatti J et al. Differential localization of von Willebrand factor, fibronectin and 13-HODE in human endothelial cell cultures. 1990 Histochemistry pmid:2185200
Schneider C and Pozzi A Cyclooxygenases and lipoxygenases in cancer. 2011 Cancer Metastasis Rev. pmid:22002716
Kämmerer I et al. 13-hydroxy linoleic acid increases expression of the cholesterol transporters ABCA1, ABCG1 and SR-BI and stimulates apoA-I-dependent cholesterol efflux in RAW264.7 macrophages. 2011 Lipids Health Dis pmid:22129452
Ivanov I et al. Ligand-induced formation of transient dimers of mammalian 12/15-lipoxygenase: a key to allosteric behavior of this class of enzymes? 2012 Proteins pmid:22189720
Viita H et al. 15-Lipoxygenase-1 induces lipid peroxidation and apoptosis, and improves survival in rat malignant glioma. 2012 Jan-Feb In Vivo pmid:22210710
Hadjiagapiou C et al. Metabolism of 13-hydroxy-9,11-octadecadienoic acid by MOLT-4 lymphocytes. 1990 Biochim. Biophys. Acta pmid:2223855
Pollack AZ et al. Relation of blood cadmium, lead, and mercury levels to biomarkers of lipid peroxidation in premenopausal women. 2012 Am. J. Epidemiol. pmid:22302120
Bertomeu MC et al. Selective effects of dietary fats on vascular 13-HODE synthesis and platelet/vessel wall interactions. 1990 Thromb. Res. pmid:2237838
Li MY et al. Pioglitazone prevents smoking carcinogen-induced lung tumor development in mice. 2012 Curr Cancer Drug Targets pmid:22463586
Czimmerer Z et al. Identification of novel markers of alternative activation and potential endogenous PPARγ ligand production mechanisms in human IL-4 stimulated differentiating macrophages. 2012 Immunobiology pmid:22954708
Ramsden CE et al. Lowering dietary linoleic acid reduces bioactive oxidized linoleic acid metabolites in humans. 2012 Oct-Nov Prostaglandins Leukot. Essent. Fatty Acids pmid:22959954
Zuo X and Shureiqi I Eicosanoid profiling in colon cancer: emergence of a pattern. 2013 Jul-Aug Prostaglandins Other Lipid Mediat. pmid:22960430
Ruparel S et al. The cytochrome P450 inhibitor, ketoconazole, inhibits oxidized linoleic acid metabolite-mediated peripheral inflammatory pain. 2012 Mol Pain pmid:23006841
Yuan ZX et al. Identification and profiling of targeted oxidized linoleic acid metabolites in rat plasma by quadrupole time-of-flight mass spectrometry. 2013 Biomed. Chromatogr. pmid:23037960
Tavakoli-Yaraki M et al. Induction of apoptosis by Trichostatin A in human breast cancer cell lines: involvement of 15-Lox-1. 2013 Tumour Biol. pmid:23055198
Weber E et al. Relationship between vessel wall 13-HODE synthesis and vessel wall thrombogenicity following injury: influence of salicylate and dipyridamole treatment. 1990 Thromb. Res. pmid:2315893
Rolin J et al. Oxidized lipids and lysophosphatidylcholine induce the chemotaxis and intracellular calcium influx in natural killer cells. 2013 Immunobiology pmid:23200035
Alsalem M et al. The contribution of the endogenous TRPV1 ligands 9-HODE and 13-HODE to nociceptive processing and their role in peripheral inflammatory pain mechanisms. 2013 Br. J. Pharmacol. pmid:23278358
Mabalirajan U et al. 12/15-lipoxygenase expressed in non-epithelial cells causes airway epithelial injury in asthma. 2013 Sci Rep pmid:23528921
Idborg H et al. Effects of mPGES-1 deletion on eicosanoid and fatty acid profiles in mice. 2013 Prostaglandins Other Lipid Mediat. pmid:23916744