alpha-artemisic acid

Alpha-artemisic acid is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 1126 references associated with alpha-artemisic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for alpha-artemisic acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with alpha-artemisic acid

MeSH term MeSH ID Detail
Colonic Neoplasms D003110 161 associated lipids
Adenocarcinoma D000230 166 associated lipids
Lung Neoplasms D008175 171 associated lipids
Per page 10 20 | Total 13

NCBI Entrez Crosslinks

All references with alpha-artemisic acid

Download all related citations
Per page 10 20 50 100 | Total 261
Authors Title Published Journal PubMed Link
pmid:25330944
pmid:25586578
pmid:28923202
pmid:27018002
pmid:25381799
pmid:28723225
pmid:26498702
pmid:25192306
pmid:28886714
pmid:28259037
pmid:
Tímár J et al. Key determinants of the invasion mechanism of melanoma. Role for a new signaling pathway. 1997 Adv. Exp. Med. Biol. pmid:9321968
Brinckmann R and Kühn H Regulation of 15-lipoxygenase expression by cytokines. 1997 Adv. Exp. Med. Biol. pmid:9547609
Buchanan MR and Brister SJ Effects of 13-HODE and other momohydroxides on integrin/ligand binding: implications for cell cell interactions. 1997 Adv. Exp. Med. Biol. pmid:9561149
Ziboh VA 13-Hydroxyoctadecadienoic acid reverses epidermal hyperproliferation via selective inhibition of membrane protein kinase C-beta activity. 1997 Adv. Exp. Med. Biol. pmid:9561152
Schade UF et al. The role of 13-hydroxylinoleic acid in the activation of macrophages by lipopolysaccharide. 1990 Adv. Exp. Med. Biol. pmid:2109506
Engels F et al. Airway hyperresponsiveness induced by 13-hydroxyoctadecadienoic acid (13-HODE) is mediated by sensory neuropeptides. 1995 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:7732872
Buchanan MR et al. Endothelial cell 13-HODE synthesis and tumor cell endothelial cell adhesion. 1991 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:1705085
Brister SJ et al. 13-HODE synthesis in internal mammary arteries and saphenous veins: implications in cardiovascular surgery. 1991 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:1825395
Buchanan MR et al. Fatty acid metabolism and cell/cell interactions. 1990 Agents Actions pmid:2183576
Engels F et al. Modulation of guinea pig airway reactivity by the linoleic acid metabolite 13-hydroxy-octadecadienoic acid (13-HODE). 1990 Agents Actions Suppl. pmid:2080746
Spindler S and Reddy RG Effect of pH on enzyme immunoassay and analysis of urine. 1998 Am Clin Lab pmid:10345154
Ziboh VA et al. Metabolism of polyunsaturated fatty acids by skin epidermal enzymes: generation of antiinflammatory and antiproliferative metabolites. 2000 Am. J. Clin. Nutr. pmid:10617998
Pollack AZ et al. Relation of blood cadmium, lead, and mercury levels to biomarkers of lipid peroxidation in premenopausal women. 2012 Am. J. Epidemiol. pmid:22302120
Wang D et al. Asymmetric dimethylarginine and lipid peroxidation products in early autosomal dominant polycystic kidney disease. 2008 Am. J. Kidney Dis. pmid:18215696
Stoll LL et al. 13-HODE increases intracellular calcium in vascular smooth muscle cells. 1994 Am. J. Physiol. pmid:8178971
Collins JF et al. Induction of arachidonate 12-lipoxygenase (Alox15) in intestine of iron-deficient rats correlates with the production of biologically active lipid mediators. 2008 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:18258795
Cabral M et al. Differential cell growth/apoptosis behavior of 13-hydroxyoctadecadienoic acid enantiomers in a colorectal cancer cell line. 2014 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:25035111
Nieman DC et al. Metabolomics approach to assessing plasma 13- and 9-hydroxy-octadecadienoic acid and linoleic acid metabolite responses to 75-km cycling. 2014 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:24760997
Wang D et al. Asymmetric dimethylarginine, oxidative stress, and vascular nitric oxide synthase in essential hypertension. 2009 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:18685064
Hill EM et al. Changes in expression of 15-lipoxygenase and prostaglandin-H synthase during differentiation of human tracheobronchial epithelial cells. 1998 Am. J. Respir. Cell Mol. Biol. pmid:9569236
Li MY et al. Roles of peroxisome proliferator-activated receptor-alpha and -gamma in the development of non-small cell lung cancer. 2010 Am. J. Respir. Cell Mol. Biol. pmid:20081051
Lehmann WD et al. Profiling assay for lipoxygenase products of linoleic and arachidonic acid by gas chromatography-mass spectrometry. 1992 Anal. Biochem. pmid:1514683
Lehmann WD et al. Quantitative lipoxygenase product profiling by gas chromatography negative-ion chemical ionization mass spectrometry. 1995 Anal. Biochem. pmid:7710076
Jameson JB et al. A high-throughput mass spectrometric assay for discovery of human lipoxygenase inhibitors and allosteric effectors. 2015 Anal. Biochem. pmid:25712042
Cho H et al. Nonradiometric HPLC measurement of 13(S)-hydroxyoctadecadienoic acid from rat tissues. 2003 Anal. Biochem. pmid:12782030
Botting R and Vane JR Mediators and the anti-thrombotic properties of the vascular endothelium. 1989 Ann. Med. pmid:2647108
Chu J and Praticò D 5-lipoxygenase as an endogenous modulator of amyloid β formation in vivo. 2011 Ann. Neurol. pmid:21280074
Heslin MJ et al. Tumor-associated down-regulation of 15-lipoxygenase-1 is reversed by celecoxib in colorectal cancer. 2005 Ann. Surg. pmid:15912043
Herlin T et al. Changes in lipoxygenase products from synovial fluid in carrageenan induced arthritis in dogs. 1988 APMIS pmid:2841956
Glasgow WC and Eling TE Structure-activity relationship for potentiation of EGF-dependent mitogenesis by oxygenated metabolites of linoleic acid. 1994 Arch. Biochem. Biophys. pmid:8203891
Aznar-Salatti J et al. Platelet adhesion to exposed endothelial cell extracellular matrixes is influenced by the method of preparation. 1991 Mar-Apr Arterioscler. Thromb. pmid:1998660
Gniwotta C et al. Prostaglandin F2-like compounds, F2-isoprostanes, are present in increased amounts in human atherosclerotic lesions. 1997 Arterioscler. Thromb. Vasc. Biol. pmid:9409317
Chabane N et al. Human articular chondrocytes express 15-lipoxygenase-1 and -2: potential role in osteoarthritis. 2009 Arthritis Res. Ther. pmid:19296842
Baer AN et al. In vivo activation of an omega-6 oxygenase in human skin. 1991 Biochem. Biophys. Res. Commun. pmid:1930242
Schade UF et al. Increased 13-hydroxyoctadecadienoic acid content in lipopolysaccharide stimulated macrophages. 1987 Biochem. Biophys. Res. Commun. pmid:3632694
Spindler SA et al. Significance and immunoassay of 9- and 13-hydroxyoctadecadienoic acids. 1996 Biochem. Biophys. Res. Commun. pmid:8573129
Cho Y and Ziboh VA 13-Hydroxyoctadecadienoic acid reverses epidermal hyperproliferation via selective inhibition of protein kinase C-beta activity. 1994 Biochem. Biophys. Res. Commun. pmid:8198583
Wölle J et al. Transient overexpression of human 15-lipoxygenase in aortic endothelial cells enhances tumor necrosis factor-induced vascular cell adhesion molecule-1 gene expression. 1996 Biochem. Biophys. Res. Commun. pmid:8645302
Chen NG et al. PPARgamma agonists enhance human vascular endothelial adhesiveness by increasing ICAM-1 expression. 1999 Biochem. Biophys. Res. Commun. pmid:10512746
Stepień K et al. Reduction of 13-hydroperoxy-9,11-octadecadienoic acid by dopamine-melanin. 1998 Biochem. Biophys. Res. Commun. pmid:9535742
Jang MK et al. Regulation of ferritin light chain gene expression by oxidized low-density lipoproteins in human monocytic THP-1 cells. 1999 Biochem. Biophys. Res. Commun. pmid:10558912
Spindler SA et al. Production of 13-hydroxyoctadecadienoic acid (13-HODE) by prostate tumors and cell lines. 1997 Biochem. Biophys. Res. Commun. pmid:9367845
Pongracz J and Lord JM The lipoxygenase product 13-hydroxyoctadecadienoic acid (13-HODE) is a selective inhibitor of classical PKC isoenzymes. 1999 Biochem. Biophys. Res. Commun. pmid:10079174
Jostarndt K et al. Dissociation of apoptosis induction and CD36 upregulation by enzymatically modified low-density lipoprotein in monocytic cells. 2002 Biochem. Biophys. Res. Commun. pmid:11798172
Azuma Y et al. 15-Deoxy-delta(12,14)-prostaglandin J(2) inhibits IL-10 and IL-12 production by macrophages. 2001 Biochem. Biophys. Res. Commun. pmid:11327705
Yamaja Setty BN et al. 13-Hydroxyoctadeca-9,11-dienoic acid (13-HODE) inhibits thromboxane A2 synthesis, and stimulates 12-HETE production in human platelets. 1987 Biochem. Biophys. Res. Commun. pmid:3120708
Reinaud O et al. Oxidative metabolism of linoleic acid by human leukocytes. 1989 Biochem. Biophys. Res. Commun. pmid:2735926
Reddy N et al. Characterization of a 15-lipoxygenase in human breast carcinoma BT-20 cells: stimulation of 13-HODE formation by TGF alpha/EGF. 1997 Biochem. Biophys. Res. Commun. pmid:9070230
Setty BN et al. 13-Hydroxyoctadecadienoic acid (13-HODE) stimulates prostacyclin production by endothelial cells. 1987 Biochem. Biophys. Res. Commun. pmid:3113422
Bürger F et al. Positional- and stereo-selectivity of fatty acid oxygenation catalysed by mouse (12S)-lipoxygenase isoenzymes. 2000 Biochem. J. pmid:10816426
Jostarndt K et al. Enzymatically modified low-density lipoprotein upregulates CD36 in low-differentiated monocytic cells in a peroxisome proliferator-activated receptor-gamma-dependent way. 2004 Biochem. Pharmacol. pmid:15104237
De Meyer GR et al. Early atherosclerosis is accompanied by a decreased rather than an increased accumulation of fatty acid hydroxyderivatives. 1991 Biochem. Pharmacol. pmid:1650207
Altmann R et al. 13-Oxo-ODE is an endogenous ligand for PPARgamma in human colonic epithelial cells. 2007 Biochem. Pharmacol. pmid:17604003
Neuzil J et al. Secretory phospholipase A2 and lipoprotein lipase enhance 15-lipoxygenase-induced enzymic and nonenzymic lipid peroxidation in low-density lipoproteins. 1998 Biochemistry pmid:9636068
Wecksler AT et al. Mechanistic investigations of human reticulocyte 15- and platelet 12-lipoxygenases with arachidonic acid. 2009 Biochemistry pmid:19469483
Chechetkin IR et al. The novel pathway for ketodiene oxylipin biosynthesis in Jerusalem artichoke (Helianthus tuberosus) tubers. 2004 Biochim. Biophys. Acta pmid:15522817
Baer AN et al. Stereospecificity of the hydroxyeicosatetraenoic and hydroxyoctadecadienoic acids produced by cultured bovine endothelial cells. 1991 Biochim. Biophys. Acta pmid:1892877
Haas TA et al. Cyclic AMP regulation of endothelial cell triacylglycerol turnover, 13-hydroxyoctadecadienoic acid (13-HODE) synthesis and endothelial cell thrombogenicity. 1990 Biochim. Biophys. Acta pmid:2155665
Claeys M et al. Metabolic profile of linoleic acid in porcine leukocytes through the lipoxygenase pathway. 1985 Biochim. Biophys. Acta pmid:2996610
Haas TA et al. Binding of 13-HODE and 5-, 12- and 15-HETE to endothelial cells and subsequent platelet, neutrophil and tumor cell adhesion. 1988 Biochim. Biophys. Acta pmid:3390452
Cowlen MS and Eling TE Effects of prostaglandins and hydroxyoctadecadienoic acid on epidermal growth factor-dependent DNA synthesis and c-myc proto-oncogene expression in Syrian hamster embryo cells. 1993 Biochim. Biophys. Acta pmid:8373802
Hamberg M and Samuelsson B Stereochemistry in the formation of 9-hydroxy-10,12-octadecadienoic acid and 13-hydroxy-9,11-octadecadienoic acid from linoleic acid by fatty acid cyclooxygenase. 1980 Biochim. Biophys. Acta pmid:6768399
Carpenter KL et al. Lipids and oxidised lipids in human atheroma and normal aorta. 1993 Biochim. Biophys. Acta pmid:8466938
Seeley SK et al. Metabolism of oxidized linoleic acid by glutathione transferases: peroxidase activity toward 13-hydroperoxyoctadecadienoic acid. 2006 Biochim. Biophys. Acta pmid:16624487
Truitt A et al. Antiplatelet effects of conjugated linoleic acid isomers. 1999 Biochim. Biophys. Acta pmid:10320806
Earles SM et al. Metabolism of oxidized linoleic acid: characterization of 13-hydroxyoctadecadienoic acid dehydrogenase activity from rat colonic tissue. 1991 Biochim. Biophys. Acta pmid:1998735
Carpenter KL et al. Lipids and oxidised lipids in human atherosclerotic lesions at different stages of development. 1995 Biochim. Biophys. Acta pmid:7766691
Claeys M et al. Characterization of monohydroxylated lipoxygenase metabolites of arachidonic and linoleic acid in rabbit peritoneal tissue. 1982 Biochim. Biophys. Acta pmid:6814493
Akiba S et al. Translocation of phospholipase A2 to membranes by oxidized LDL and hydroxyoctadecadienoic acid to contribute to cholesteryl ester formation. 2004 Biochim. Biophys. Acta pmid:15522824
Kim JH et al. Attenuation of breast tumor cell growth by conjugated linoleic acid via inhibition of 5-lipoxygenase activating protein. 2005 Biochim. Biophys. Acta pmid:16185917
Hadjiagapiou C et al. Metabolism of 13-hydroxy-9,11-octadecadienoic acid by MOLT-4 lymphocytes. 1990 Biochim. Biophys. Acta pmid:2223855
Blackburn ML et al. Specific protein targets of 13-oxooctadecadienoic acid (13-OXO) and export of the 13-OXO-glutathione conjugate in HT-29 cells. 1999 Biochim. Biophys. Acta pmid:10521706
Nugteren DH and Kivits GA Conversion of linoleic acid and arachidonic acid by skin epidermal lipoxygenases. 1987 Biochim. Biophys. Acta pmid:3113487
Friedrichs B et al. 13-HPODE and 13-HODE modulate cytokine-induced expression of endothelial cell adhesion molecules differently. 1999 Biofactors pmid:10221158
Terao J et al. Glutathione peroxidase mimics as novel antioxidants from vegetables. 2005 Biofactors pmid:15817993
Müller C et al. Perturbation of lipid metabolism by linoleic acid hydroperoxide in CaCo-2 cells. 2002 Mar-Apr Biol. Chem. pmid:12033453
Yuan ZX et al. Identification and profiling of targeted oxidized linoleic acid metabolites in rat plasma by quadrupole time-of-flight mass spectrometry. 2013 Biomed. Chromatogr. pmid:23037960
Buchanan MR et al. Localization of 13-hydroxyoctadecadienoic acid and the vitronectin receptor in human endothelial cells and endothelial cell/platelet interactions in vitro. 1993 Blood pmid:7685202
Huang FC and Schwab W Cloning and characterization of a 9-lipoxygenase gene induced by pathogen attack from Nicotiana benthamiana for biotechnological application. 2011 BMC Biotechnol. pmid:21450085
Camp RD and Fincham NJ Inhibition of ionophore-stimulated leukotriene B4 production in human leucocytes by monohydroxy fatty acids. 1985 Br. J. Pharmacol. pmid:2994785
De Meyer GR et al. The role of endothelial cells in the relaxations induced by 13-hydroxy- and 13-hydroperoxylinoleic acid in canine arteries. 1992 Br. J. Pharmacol. pmid:1422601
Alsalem M et al. The contribution of the endogenous TRPV1 ligands 9-HODE and 13-HODE to nociceptive processing and their role in peripheral inflammatory pain mechanisms. 2013 Br. J. Pharmacol. pmid:23278358
Liu SH et al. Honokiol inhibits gastric tumourigenesis by activation of 15-lipoxygenase-1 and consequent inhibition of peroxisome proliferator-activated receptor-gamma and COX-2-dependent signals. 2010 Br. J. Pharmacol. pmid:20649594
Blask DE et al. Growth and fatty acid metabolism of human breast cancer (MCF-7) xenografts in nude rats: impact of constant light-induced nocturnal melatonin suppression. 2003 Breast Cancer Res. Treat. pmid:12846415
Silverman AL et al. Decreased levels of 13-hydroxyoctadecadienoic acid (13-HODE) dehydrogenase in neoplastic tissue of human colon biopsies. 1996 Cancer Epidemiol. Biomarkers Prev. pmid:8770467
Dauchy RT et al. Differential inhibition of fatty acid transport in tissue-isolated steroid receptor negative human breast cancer xenografts perfused in situ with isomers of conjugated linoleic acid. 2004 Cancer Lett. pmid:15145516
Dauchy RT et al. Dim light during darkness stimulates tumor progression by enhancing tumor fatty acid uptake and metabolism. 1999 Cancer Lett. pmid:10529012
Schneider C and Pozzi A Cyclooxygenases and lipoxygenases in cancer. 2011 Cancer Metastasis Rev. pmid:22002716
Shureiqi I et al. Profiling lipoxygenase metabolism in specific steps of colorectal tumorigenesis. 2010 Cancer Prev Res (Phila) pmid:20570882