alpha-artemisic acid

Alpha-artemisic acid is a lipid of Fatty Acyls (FA) class.

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Current reference collection contains 1126 references associated with alpha-artemisic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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Here are additional resources we collected from PubChem and MeSH for alpha-artemisic acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with alpha-artemisic acid

MeSH term MeSH ID Detail
Colonic Neoplasms D003110 161 associated lipids
Adenocarcinoma D000230 166 associated lipids
Lung Neoplasms D008175 171 associated lipids
Per page 10 20 | Total 13

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Askari B et al. Oleate and linoleate enhance the growth-promoting effects of insulin-like growth factor-I through a phospholipase D-dependent pathway in arterial smooth muscle cells. 2002 J. Biol. Chem. pmid:12138107
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Buckley TL et al. 13-hydroxyoctadecadienoic acid attenuates oedema formation induced by leukotriene B4 in vivo in rabbit skin. 1992 Eur. J. Pharmacol. pmid:1330604
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Jude AR et al. 13-hydroxy- and 13-oxooctadecadienoic acids: novel substrates for human UDP-glucuronosyltransferases. 2001 Drug Metab. Dispos. pmid:11302930
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De Meyer GR et al. Neointima formation impairs endothelial muscarinic receptors while enhancing prostacyclin-mediated responses in the rabbit carotid artery. 1991 Circ. Res. pmid:1645234
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Schneider C et al. Autoxidative transformation of chiral omega6 hydroxy linoleic and arachidonic acids to chiral 4-hydroxy-2E-nonenal. 2004 Chem. Res. Toxicol. pmid:15257619
Jira W et al. Strong increase in hydroxy fatty acids derived from linoleic acid in human low density lipoproteins of atherosclerotic patients. 1998 Chem. Phys. Lipids pmid:9488997
Batna A et al. Lipid peroxidation in presence of ebselen. 1997 Chem. Phys. Lipids pmid:9275309
Jira W et al. Increased levels of lipid oxidation products in low density lipoproteins of patients suffering from rheumatoid arthritis. 1997 Chem. Phys. Lipids pmid:9219348
Manini P et al. Biomimetic nitration of the linoleic acid metabolite 13-hydroxyoctadecadienoic acid: isolation and spectral characterization of novel chain-rearranged epoxy nitro derivatives. 2008 Chem. Phys. Lipids pmid:18320610
Manini P et al. Free radical oxidation of coriolic acid (13-(S)-hydroxy-9Z,11E-octadecadienoic acid). 2005 Chem. Phys. Lipids pmid:15784234
Mani I et al. Upregulation of nuclear PKC and MAP-kinase during hyperproliferation of guinea pig epidermis: modulation by 13-(S)-hydroxyoctadecadienoic acid (13-HODE). 1998 Cell. Signal. pmid:9481490
Liu B et al. Lipoxygenase metabolites of arachidonic and linoleic acids modulate the adhesion of tumor cells to endothelium via regulation of protein kinase C. 1991 Cell Regul. pmid:1801923
Nagy L et al. Oxidized LDL regulates macrophage gene expression through ligand activation of PPARgamma. 1998 Cell pmid:9568715
Kelavkar UP et al. Overexpression of 15-lipoxygenase-1 in PC-3 human prostate cancer cells increases tumorigenesis. 2001 Carcinogenesis pmid:11698337
Blask DE et al. Melatonin uptake and growth prevention in rat hepatoma 7288CTC in response to dietary melatonin: melatonin receptor-mediated inhibition of tumor linoleic acid metabolism to the growth signaling molecule 13-hydroxyoctadecadienoic acid and the potential role of phytomelatonin. 2004 Carcinogenesis pmid:14754876
Shureiqi I et al. Decreased 13-S-hydroxyoctadecadienoic acid levels and 15-lipoxygenase-1 expression in human colon cancers. 1999 Carcinogenesis pmid:10506115
Wu J et al. 15-Lipoxygenase-1 mediates cyclooxygenase-2 inhibitor-induced apoptosis in gastric cancer. 2003 Carcinogenesis pmid:12584173
Cimen I et al. 15-Lipoxygenase-1 expression suppresses the invasive properties of colorectal carcinoma cell lines HCT-116 and HT-29. 2009 Cancer Sci. pmid:19775287
Shureiqi I et al. 15-Lipoxygenase-1 mediates nonsteroidal anti-inflammatory drug-induced apoptosis independently of cyclooxygenase-2 in colon cancer cells. 2000 Cancer Res. pmid:11156377
Grossi IM et al. Bidirectional control of membrane expression and/or activation of the tumor cell IRGpIIb/IIIa receptor and tumor cell adhesion by lipoxygenase products of arachidonic acid and linoleic acid. 1989 Cancer Res. pmid:2492204
Shureiqi I et al. Nonsteroidal anti-inflammatory drugs induce apoptosis in esophageal cancer cells by restoring 15-lipoxygenase-1 expression. 2001 Cancer Res. pmid:11406566
Müller K et al. Modulation of epidermal tumor development caused by targeted overexpression of epidermis-type 12S-lipoxygenase. 2002 Cancer Res. pmid:12183416
Sauer LA et al. 13-Hydroxyoctadecadienoic acid is the mitogenic signal for linoleic acid-dependent growth in rat hepatoma 7288CTC in vivo. 1999 Cancer Res. pmid:10493526
Blask DE et al. Melatonin inhibition of cancer growth in vivo involves suppression of tumor fatty acid metabolism via melatonin receptor-mediated signal transduction events. 1999 Cancer Res. pmid:10493527
Hsi LC et al. The histone deacetylase inhibitor suberoylanilide hydroxamic acid induces apoptosis via induction of 15-lipoxygenase-1 in colorectal cancer cells. 2004 Cancer Res. pmid:15574791
Shureiqi I et al. The critical role of 15-lipoxygenase-1 in colorectal epithelial cell terminal differentiation and tumorigenesis. 2005 Cancer Res. pmid:16357157
Sauer LA et al. Mechanism for the antitumor and anticachectic effects of n-3 fatty acids. 2000 Cancer Res. pmid:11016660
Shureiqi I et al. Profiling lipoxygenase metabolism in specific steps of colorectal tumorigenesis. 2010 Cancer Prev Res (Phila) pmid:20570882
Schneider C and Pozzi A Cyclooxygenases and lipoxygenases in cancer. 2011 Cancer Metastasis Rev. pmid:22002716
Dauchy RT et al. Differential inhibition of fatty acid transport in tissue-isolated steroid receptor negative human breast cancer xenografts perfused in situ with isomers of conjugated linoleic acid. 2004 Cancer Lett. pmid:15145516
Dauchy RT et al. Dim light during darkness stimulates tumor progression by enhancing tumor fatty acid uptake and metabolism. 1999 Cancer Lett. pmid:10529012
Silverman AL et al. Decreased levels of 13-hydroxyoctadecadienoic acid (13-HODE) dehydrogenase in neoplastic tissue of human colon biopsies. 1996 Cancer Epidemiol. Biomarkers Prev. pmid:8770467
Blask DE et al. Growth and fatty acid metabolism of human breast cancer (MCF-7) xenografts in nude rats: impact of constant light-induced nocturnal melatonin suppression. 2003 Breast Cancer Res. Treat. pmid:12846415
Camp RD and Fincham NJ Inhibition of ionophore-stimulated leukotriene B4 production in human leucocytes by monohydroxy fatty acids. 1985 Br. J. Pharmacol. pmid:2994785
De Meyer GR et al. The role of endothelial cells in the relaxations induced by 13-hydroxy- and 13-hydroperoxylinoleic acid in canine arteries. 1992 Br. J. Pharmacol. pmid:1422601
Alsalem M et al. The contribution of the endogenous TRPV1 ligands 9-HODE and 13-HODE to nociceptive processing and their role in peripheral inflammatory pain mechanisms. 2013 Br. J. Pharmacol. pmid:23278358
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Buchanan MR et al. Localization of 13-hydroxyoctadecadienoic acid and the vitronectin receptor in human endothelial cells and endothelial cell/platelet interactions in vitro. 1993 Blood pmid:7685202
Yuan ZX et al. Identification and profiling of targeted oxidized linoleic acid metabolites in rat plasma by quadrupole time-of-flight mass spectrometry. 2013 Biomed. Chromatogr. pmid:23037960
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Friedrichs B et al. 13-HPODE and 13-HODE modulate cytokine-induced expression of endothelial cell adhesion molecules differently. 1999 Biofactors pmid:10221158
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Chechetkin IR et al. The novel pathway for ketodiene oxylipin biosynthesis in Jerusalem artichoke (Helianthus tuberosus) tubers. 2004 Biochim. Biophys. Acta pmid:15522817
Baer AN et al. Stereospecificity of the hydroxyeicosatetraenoic and hydroxyoctadecadienoic acids produced by cultured bovine endothelial cells. 1991 Biochim. Biophys. Acta pmid:1892877
Haas TA et al. Cyclic AMP regulation of endothelial cell triacylglycerol turnover, 13-hydroxyoctadecadienoic acid (13-HODE) synthesis and endothelial cell thrombogenicity. 1990 Biochim. Biophys. Acta pmid:2155665
Claeys M et al. Metabolic profile of linoleic acid in porcine leukocytes through the lipoxygenase pathway. 1985 Biochim. Biophys. Acta pmid:2996610
Haas TA et al. Binding of 13-HODE and 5-, 12- and 15-HETE to endothelial cells and subsequent platelet, neutrophil and tumor cell adhesion. 1988 Biochim. Biophys. Acta pmid:3390452
Cowlen MS and Eling TE Effects of prostaglandins and hydroxyoctadecadienoic acid on epidermal growth factor-dependent DNA synthesis and c-myc proto-oncogene expression in Syrian hamster embryo cells. 1993 Biochim. Biophys. Acta pmid:8373802
Hamberg M and Samuelsson B Stereochemistry in the formation of 9-hydroxy-10,12-octadecadienoic acid and 13-hydroxy-9,11-octadecadienoic acid from linoleic acid by fatty acid cyclooxygenase. 1980 Biochim. Biophys. Acta pmid:6768399
Carpenter KL et al. Lipids and oxidised lipids in human atheroma and normal aorta. 1993 Biochim. Biophys. Acta pmid:8466938
Seeley SK et al. Metabolism of oxidized linoleic acid by glutathione transferases: peroxidase activity toward 13-hydroperoxyoctadecadienoic acid. 2006 Biochim. Biophys. Acta pmid:16624487
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Nugteren DH and Kivits GA Conversion of linoleic acid and arachidonic acid by skin epidermal lipoxygenases. 1987 Biochim. Biophys. Acta pmid:3113487
Neuzil J et al. Secretory phospholipase A2 and lipoprotein lipase enhance 15-lipoxygenase-induced enzymic and nonenzymic lipid peroxidation in low-density lipoproteins. 1998 Biochemistry pmid:9636068
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De Meyer GR et al. Early atherosclerosis is accompanied by a decreased rather than an increased accumulation of fatty acid hydroxyderivatives. 1991 Biochem. Pharmacol. pmid:1650207
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