alpha-artemisic acid

Alpha-artemisic acid is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 1126 references associated with alpha-artemisic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for alpha-artemisic acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with alpha-artemisic acid

MeSH term MeSH ID Detail
Familial Mediterranean Fever D010505 12 associated lipids
Colorectal Neoplasms D015179 10 associated lipids
Adenomatous Polyps D018256 4 associated lipids
Per page 10 20 | Total 13

NCBI Entrez Crosslinks

All references with alpha-artemisic acid

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Authors Title Published Journal PubMed Link
Ruparel S et al. The cytochrome P450 inhibitor, ketoconazole, inhibits oxidized linoleic acid metabolite-mediated peripheral inflammatory pain. 2012 Mol Pain pmid:23006841
Buchanan MR and Bastida E Endothelium and underlying membrane reactivity with platelets, leukocytes and tumor cells: regulation by the lipoxygenase-derived fatty acid metabolites, 13-HODE and HETES. 1988 Med. Hypotheses pmid:3147361
Zha K et al. LDL in patients with subclinical hypothyroidism shows increased lipid peroxidation. 2015 Lipids Health Dis pmid:26302822
Kämmerer I et al. 13-hydroxy linoleic acid increases expression of the cholesterol transporters ABCA1, ABCG1 and SR-BI and stimulates apoA-I-dependent cholesterol efflux in RAW264.7 macrophages. 2011 Lipids Health Dis pmid:22129452
Bull AW et al. Regulation of the induction of ornithine decarboxylase in short-term rat colon organ culture by dexamethasone and 13-hydroxyoctadecadienoic acid (13-HODE). 1993 Life Sci. pmid:8326823
Dauchy RT et al. Light contamination during the dark phase in "photoperiodically controlled" animal rooms: effect on tumor growth and metabolism in rats. 1997 Lab. Anim. Sci. pmid:9355094
Stachowska E et al. Apolipoprotein E4 allele is associated with substantial changes in the plasma lipids and hyaluronic acid content in patients with nonalcoholic fatty liver disease. 2013 J. Physiol. Pharmacol. pmid:24388885
Sauer LA et al. Dietary factors and growth and metabolism in experimental tumors. 2007 J. Nutr. Biochem. pmid:17418560
Cho Y and Ziboh VA Nutritional modulation of guinea pig skin hyperproliferation by essential fatty acid deficiency is associated with selective down regulation of protein kinase C-beta. 1995 J. Nutr. pmid:7472653
Fischer SM et al. Arachidonate has protumor-promoting action that is inhibited by linoleate in mouse skin carcinogenesis. 1996 J. Nutr. pmid:8642440
Khan-Merchant N et al. Oxidized fatty acids promote atherosclerosis only in the presence of dietary cholesterol in low-density lipoprotein receptor knockout mice. 2002 J. Nutr. pmid:12421837
Sauer LA et al. Eicosapentaenoic acid suppresses cell proliferation in MCF-7 human breast cancer xenografts in nude rats via a pertussis toxin-sensitive signal transduction pathway. 2005 J. Nutr. pmid:16140887
Li D et al. Purified anthocyanin supplementation reduces dyslipidemia, enhances antioxidant capacity, and prevents insulin resistance in diabetic patients. 2015 J. Nutr. pmid:25833778
Shureiqi I et al. 15-LOX-1: a novel molecular target of nonsteroidal anti-inflammatory drug-induced apoptosis in colorectal cancer cells. 2000 J. Natl. Cancer Inst. pmid:10904086
Cho Y and Ziboh VA Incorporation of 13-hydroxyoctadecadienoic acid (13-HODE) into epidermal ceramides and phospholipids: phospholipase C-catalyzed release of novel 13-HODE-containing diacylglycerol. 1994 J. Lipid Res. pmid:8169529
Thomas CE et al. Multiple lipid oxidation products in low density lipoproteins induce interleukin-1 beta release from human blood mononuclear cells. 1994 J. Lipid Res. pmid:8014577
Meilhac O et al. Lipid peroxides induce expression of catalase in cultured vascular cells. 2000 J. Lipid Res. pmid:10946007
Nikkari T et al. Monitoring of lipoprotein oxidation by gas chromatographic analysis of hydroxy fatty acids. 1995 J. Lipid Res. pmid:7706944
Hui R et al. Epidermal growth factor-stimulated production of esterified 13(S)-hydroxyoctadecadienoic acid is associated with tumor suppressor phenotype in Syrian hamster embryo fibroblasts. 1997 J. Lipid Res. pmid:9034199
Fang X et al. 13-(S)-hydroxyoctadecadienoic acid (13-HODE) incorporation and conversion to novel products by endothelial cells. 1999 J. Lipid Res. pmid:10191294
Akiba S et al. Oxidized LDL activates phospholipase A2 to supply fatty acids required for cholesterol esterification. 2003 J. Lipid Res. pmid:12777475
Murthy S et al. 13-hydroxy octadecadienoic acid (13-HODE) inhibits triacylglycerol-rich lipoprotein secretion by CaCo-2 cells. 1998 J. Lipid Res. pmid:9643357
Kang LT and Vanderhoek JY Mono (S) hydroxy fatty acids: novel ligands for cytosolic actin. 1998 J. Lipid Res. pmid:9684751
Folcik VA and Cathcart MK Predominance of esterified hydroperoxy-linoleic acid in human monocyte-oxidized LDL. 1994 J. Lipid Res. pmid:7806971
Baer AN et al. Stereospecificity of the products of the fatty acid oxygenases derived from psoriatic scales. 1991 J. Lipid Res. pmid:1906083
Daret D et al. Synthesis of monohydroxylated fatty acids from linoleic acid by rat aortic smooth muscle cells and tissues: influence on prostacyclin production. 1993 J. Lipid Res. pmid:8228632
van de Velde MJ et al. 13-HODE inhibits the intracellular calcium increase of activated human polymorphonuclear cells. 1994 J. Leukoc. Biol. pmid:8071595
Rolin J and Maghazachi AA Implications of chemokines, chemokine receptors, and inflammatory lipids in atherosclerosis. 2014 J. Leukoc. Biol. pmid:24493826
Duell EA et al. Determination of 5,12, and 15-lipoxygenase products in keratomed biopsies of normal and psoriatic skin. 1988 J. Invest. Dermatol. pmid:2844912
Godessart N et al. Prostaglandin H-synthase-2 is the main enzyme involved in the biosynthesis of octadecanoids from linoleic acid in human dermal fibroblasts stimulated with interleukin-1beta. 1996 J. Invest. Dermatol. pmid:8875957
Miller CC and Ziboh VA Induction of epidermal hyperproliferation by topical n-3 polyunsaturated fatty acids on guinea pig skin linked to decreased levels of 13-hydroxyoctadecadienoic acid (13-hode). 1990 J. Invest. Dermatol. pmid:2106562
Ogawa E et al. Epidermal FABP (FABP5) regulates keratinocyte differentiation by 13(S)-HODE-mediated activation of the NF-κB signaling pathway. 2011 J. Invest. Dermatol. pmid:21068754
Mani I et al. Evidence of nuclear PKC/MAP-kinase cascade in guinea pig model of epidermal hyperproliferation. 1999 J. Invest. Dermatol. pmid:9886262
Matzner Y et al. Generation of lipid neutrophil chemoattractant by irradiated bovine aortic endothelial cells. 1988 J. Immunol. pmid:3128604
Black LL et al. Cholesterol-Independent Suppression of Lymphocyte Activation, Autoimmunity, and Glomerulonephritis by Apolipoprotein A-I in Normocholesterolemic Lupus-Prone Mice. 2015 J. Immunol. pmid:26466956
Fischer B et al. Dualism of oxidized lipoproteins in provoking and attenuating the oxidative burst in macrophages: role of peroxisome proliferator-activated receptor-gamma. 2002 J. Immunol. pmid:11884452
Coutant F et al. Sensing environmental lipids by dendritic cell modulates its function. 2004 J. Immunol. pmid:14688309
Nakamura M et al. Immunocytochemical localization of platelet-type arachidonate 12-lipoxygenase in mouse blood cells. 1995 J. Histochem. Cytochem. pmid:7868854
Yoshinaga M et al. The 15-lipoxygenase-1 expression may enhance the sensitivity to non-steroidal anti-inflammatory drug-induced apoptosis in colorectal cancers from patients who are treated with the compounds. 2007 J. Gastroenterol. Hepatol. pmid:17559385
Kühn H et al. Involvement of 15-lipoxygenase in early stages of atherogenesis. 1994 J. Exp. Med. pmid:8195716
Ikawa H et al. Arachidonate 12-lipoxygenase in porcine anterior pituitary cells: its localization and possible function in gonadotrophs. 1996 J. Endocrinol. pmid:8568469
Han KH et al. Oxidized LDL reduces monocyte CCR2 expression through pathways involving peroxisome proliferator-activated receptor gamma. 2000 J. Clin. Invest. pmid:10995790
Folcik VA et al. Lipoxygenase contributes to the oxidation of lipids in human atherosclerotic plaques. 1995 J. Clin. Invest. pmid:7615823
Kühn H et al. In vivo action of 15-lipoxygenase in early stages of human atherogenesis. 1997 J. Clin. Invest. pmid:9062346
Dandona P et al. The suppressive effect of dietary restriction and weight loss in the obese on the generation of reactive oxygen species by leukocytes, lipid peroxidation, and protein carbonylation. 2001 J. Clin. Endocrinol. Metab. pmid:11232024
Aljada A et al. Nuclear factor-kappaB suppressive and inhibitor-kappaB stimulatory effects of troglitazone in obese patients with type 2 diabetes: evidence of an antiinflammatory action? 2001 J. Clin. Endocrinol. Metab. pmid:11443197
Schild RL et al. The activity of PPAR gamma in primary human trophoblasts is enhanced by oxidized lipids. 2002 J. Clin. Endocrinol. Metab. pmid:11889173
Aljada A et al. Troglitazone reduces the expression of PPARgamma while stimulating that of PPARalpha in mononuclear cells in obese subjects. 2001 J. Clin. Endocrinol. Metab. pmid:11443177
Cimen I et al. 15-lipoxygenase-1 exerts its tumor suppressive role by inhibiting nuclear factor-kappa B via activation of PPAR gamma. 2011 J. Cell. Biochem. pmid:21544861
Askari B et al. Oleate and linoleate enhance the growth-promoting effects of insulin-like growth factor-I through a phospholipase D-dependent pathway in arterial smooth muscle cells. 2002 J. Biol. Chem. pmid:12138107