alpha-artemisic acid

Alpha-artemisic acid is a lipid of Fatty Acyls (FA) class.

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There are no associated biomedical information in the current reference collection.

Current reference collection contains 1126 references associated with alpha-artemisic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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Here are additional resources we collected from PubChem and MeSH for alpha-artemisic acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with alpha-artemisic acid

MeSH term MeSH ID Detail
Zellweger Syndrome D015211 39 associated lipids
Adenomatous Polyposis Coli D011125 16 associated lipids
Adenomatous Polyps D018256 4 associated lipids
Per page 10 20 | Total 13

NCBI Entrez Crosslinks

All references with alpha-artemisic acid

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Authors Title Published Journal PubMed Link
Buchanan MR et al. 13-Hydroxyoctadecadienoic acid is the vessel wall chemorepellant factor, LOX. 1985 J. Biol. Chem. pmid:3934168
Ek-Von Mentzer BA et al. Binding of 13-HODE and 15-HETE to phospholipid bilayers, albumin, and intracellular fatty acid binding proteins. implications for transmembrane and intracellular transport and for protection from lipid peroxidation. 2001 J. Biol. Chem. pmid:11278949
Hsi LC et al. 15-lipoxygenase-1 metabolites down-regulate peroxisome proliferator-activated receptor gamma via the MAPK signaling pathway. 2001 J. Biol. Chem. pmid:11447213
Kim YS et al. The orphan nuclear receptor small heterodimer partner as a novel coregulator of nuclear factor-kappa b in oxidized low density lipoprotein-treated macrophage cell line RAW 264.7. 2001 J. Biol. Chem. pmid:11448950
Hsi LC et al. Opposing effects of 15-lipoxygenase-1 and -2 metabolites on MAPK signaling in prostate. Alteration in peroxisome proliferator-activated receptor gamma. 2002 J. Biol. Chem. pmid:12189136
Hatley ME et al. Increased production of 12/15 lipoxygenase eicosanoids accelerates monocyte/endothelial interactions in diabetic db/db mice. 2003 J. Biol. Chem. pmid:12734208
Mabalirajan U et al. Effects of vitamin E on mitochondrial dysfunction and asthma features in an experimental allergic murine model. 2009 J. Appl. Physiol. pmid:19628725
Hübke H et al. Characterization and quantification of free and esterified 9- and 13-hydroxyoctadecadienoic acids (HODE) in barley, germinating barley, and finished malt. 2005 J. Agric. Food Chem. pmid:15740040
Cho H et al. Conjugated linoleic acid, cis-9,trans-11, is a substrate for pulmonary 15-lipoxygenase-1 in rat. 2005 J. Agric. Food Chem. pmid:16131140
Bastida E et al. Regulation of tumor cell adhesion by intracellular 13-HODE: 15-HETE ratio. 1990 Sep-Oct J Lipid Mediat pmid:1966807
Bastida E et al. Effects of endothelial cell treatment on 13-HODE and prostacyclin synthesis and its correlation with tumor cell-vascular endothelial cell adhesion. 1991 Invasion Metastasis pmid:1800451
Blask DE et al. Circadian stage-dependent inhibition of human breast cancer metabolism and growth by the nocturnal melatonin signal: consequences of its disruption by light at night in rats and women. 2009 Integr Cancer Ther pmid:20042410
Viita H et al. 15-Lipoxygenase-1 induces lipid peroxidation and apoptosis, and improves survival in rat malignant glioma. 2012 Jan-Feb In Vivo pmid:22210710
Czimmerer Z et al. Identification of novel markers of alternative activation and potential endogenous PPARγ ligand production mechanisms in human IL-4 stimulated differentiating macrophages. 2012 Immunobiology pmid:22954708
Rolin J et al. Oxidized lipids and lysophosphatidylcholine induce the chemotaxis and intracellular calcium influx in natural killer cells. 2013 Immunobiology pmid:23200035
Gryglewski RJ et al. Mediators produced by the endothelial cell. 1988 Hypertension pmid:3060428
Pomposiello SI et al. Linoleic acid induces relaxation and hyperpolarization of the pig coronary artery. 1998 Hypertension pmid:9461230
Aznar-Salatti J et al. Differential localization of von Willebrand factor, fibronectin and 13-HODE in human endothelial cell cultures. 1990 Histochemistry pmid:2185200
Metzger K et al. Lipoxygenase products in human saliva: patients with oral cancer compared to controls. 1995 Free Radic. Biol. Med. pmid:7744301
Guo L et al. Preferential formation of the hydroperoxide of linoleic acid in choline glycerophospholipids in human erythrocytes membrane during peroxidation with an azo initiator. 1995 Free Radic. Biol. Med. pmid:7628726
Coleman JD et al. The oxidative stress mediator 4-hydroxynonenal is an intracellular agonist of the nuclear receptor peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta). 2007 Free Radic. Biol. Med. pmid:17382197
Elékés E et al. Suppression of endotoxin mitogenicity of spleen cells by lipoxygenase inhibitors and its reversal by 13-hydroxyoctadecadienoic acid. 1993 FEMS Immunol. Med. Microbiol. pmid:8472013
van de Velde MJ et al. The linoleic acid metabolite 13-HODE modulates degranulation of human polymorphonuclear leukocytes. 1995 FEBS Lett. pmid:7649276
Inouye S Site-specific cleavage of double-strand DNA by hydroperoxide of linoleic acid. 1984 FEBS Lett. pmid:6430718
Grøn B et al. Distribution of monohydroxy fatty acids in specific human epidermal phospholipids. 1993 Exp. Dermatol. pmid:8156169
Henricks PA et al. 13-hydroxy-linoleic acid induces airway hyperreactivity to histamine in guinea-pigs. 1991 Eur. J. Pharmacol. pmid:1915571
Buckley TL et al. 13-hydroxyoctadecadienoic acid attenuates oedema formation induced by leukotriene B4 in vivo in rabbit skin. 1992 Eur. J. Pharmacol. pmid:1330604
Sakashita T et al. Essential involvement of 12-lipoxygenase in regiospecific andstereospecific oxidation of low density lipoprotein by macrophages. 1999 Eur. J. Biochem. pmid:10504415
Chouinard S et al. Isoform-specific regulation of uridine diphosphate-glucuronosyltransferase 2B enzymes in the human prostate: differential consequences for androgen and bioactive lipid inactivation. 2006 Endocrinology pmid:16887906
Schade FU et al. Lipoxygenase inhibitors but not site specific 5-lipoxygenase blockers protect against endotoxic shock and inhibit production of tumor necrosis factor. 1992 Eicosanoids pmid:1449831
Jude AR et al. 13-hydroxy- and 13-oxooctadecadienoic acids: novel substrates for human UDP-glucuronosyltransferases. 2001 Drug Metab. Dispos. pmid:11302930
Imaizumi S et al. L-4F differentially alters plasma levels of oxidized fatty acids resulting in more anti-inflammatory HDL in mice. 2010 Drug Metab Lett pmid:20642447
Li MY et al. Pioglitazone prevents smoking carcinogen-induced lung tumor development in mice. 2012 Curr Cancer Drug Targets pmid:22463586
Dauchy RT et al. Inhibition of fatty acid transport and proliferative activity in tissue-isolated human squamous cell cancer xenografts perfused in situ with melatonin or eicosapentaenoic or conjugated linoleic acids. 2007 Comp. Med. pmid:17803052
Bertomeu MC et al. Interleukin 1-induced cancer cell/endothelial cell adhesion in vitro and its relationship to metastasis in vivo: role of vessel wall 13-HODE synthesis and integrin expression. 1993 Clin. Exp. Metastasis pmid:7682484
Klawitter J et al. Pravastatin Therapy and Biomarker Changes in Children and Young Adults with Autosomal Dominant Polycystic Kidney Disease. 2015 Clin J Am Soc Nephrol pmid:26224879
De Meyer GR et al. Neointima formation impairs endothelial muscarinic receptors while enhancing prostacyclin-mediated responses in the rabbit carotid artery. 1991 Circ. Res. pmid:1645234
Liu W et al. Ex vivo oxidation in tissue and plasma assays of hydroxyoctadecadienoates: Z,E/E,E stereoisomer ratios. 2010 Chem. Res. Toxicol. pmid:20423158
Schneider C et al. Autoxidative transformation of chiral omega6 hydroxy linoleic and arachidonic acids to chiral 4-hydroxy-2E-nonenal. 2004 Chem. Res. Toxicol. pmid:15257619
Jira W et al. Strong increase in hydroxy fatty acids derived from linoleic acid in human low density lipoproteins of atherosclerotic patients. 1998 Chem. Phys. Lipids pmid:9488997
Batna A et al. Lipid peroxidation in presence of ebselen. 1997 Chem. Phys. Lipids pmid:9275309
Jira W et al. Increased levels of lipid oxidation products in low density lipoproteins of patients suffering from rheumatoid arthritis. 1997 Chem. Phys. Lipids pmid:9219348
Manini P et al. Biomimetic nitration of the linoleic acid metabolite 13-hydroxyoctadecadienoic acid: isolation and spectral characterization of novel chain-rearranged epoxy nitro derivatives. 2008 Chem. Phys. Lipids pmid:18320610
Manini P et al. Free radical oxidation of coriolic acid (13-(S)-hydroxy-9Z,11E-octadecadienoic acid). 2005 Chem. Phys. Lipids pmid:15784234
Mani I et al. Upregulation of nuclear PKC and MAP-kinase during hyperproliferation of guinea pig epidermis: modulation by 13-(S)-hydroxyoctadecadienoic acid (13-HODE). 1998 Cell. Signal. pmid:9481490
Liu B et al. Lipoxygenase metabolites of arachidonic and linoleic acids modulate the adhesion of tumor cells to endothelium via regulation of protein kinase C. 1991 Cell Regul. pmid:1801923
Nagy L et al. Oxidized LDL regulates macrophage gene expression through ligand activation of PPARgamma. 1998 Cell pmid:9568715
Kelavkar UP et al. Overexpression of 15-lipoxygenase-1 in PC-3 human prostate cancer cells increases tumorigenesis. 2001 Carcinogenesis pmid:11698337
Blask DE et al. Melatonin uptake and growth prevention in rat hepatoma 7288CTC in response to dietary melatonin: melatonin receptor-mediated inhibition of tumor linoleic acid metabolism to the growth signaling molecule 13-hydroxyoctadecadienoic acid and the potential role of phytomelatonin. 2004 Carcinogenesis pmid:14754876
Wu J et al. 15-Lipoxygenase-1 mediates cyclooxygenase-2 inhibitor-induced apoptosis in gastric cancer. 2003 Carcinogenesis pmid:12584173