| MeSH term | MeSH ID | Detail |
|---|---|---|
| Adenocarcinoma | D000230 | 166 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
| Thrombosis | D013927 | 49 associated lipids |
| Arteriosclerosis | D001161 | 86 associated lipids |
| Colorectal Neoplasms | D015179 | 10 associated lipids |
| Hypertension | D006973 | 115 associated lipids |
| Familial Mediterranean Fever | D010505 | 12 associated lipids |
| Carcinoma, Non-Small-Cell Lung | D002289 | 72 associated lipids |
alpha-artemisic acid
Alpha-artemisic acid is a lipid of Fatty Acyls (FA) class.
Cross Reference
There are no associated biomedical information in the current reference collection.
Current reference collection contains 1126 references associated with alpha-artemisic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.
Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.
Here are additional resources we collected from PubChem and MeSH for alpha-artemisic acid
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with alpha-artemisic acid
NCBI Entrez Crosslinks
All references with alpha-artemisic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| pmid: | ||||
| Pongracz J and Lord JM | The lipoxygenase product 13-hydroxyoctadecadienoic acid (13-HODE) is a selective inhibitor of classical PKC isoenzymes. | 1999 | Biochem. Biophys. Res. Commun. | pmid:10079174 |
| Fang X et al. | 13-(S)-hydroxyoctadecadienoic acid (13-HODE) incorporation and conversion to novel products by endothelial cells. | 1999 | J. Lipid Res. | pmid:10191294 |
| Friedrichs B et al. | 13-HPODE and 13-HODE modulate cytokine-induced expression of endothelial cell adhesion molecules differently. | 1999 | Biofactors | pmid:10221158 |
| Truitt A et al. | Antiplatelet effects of conjugated linoleic acid isomers. | 1999 | Biochim. Biophys. Acta | pmid:10320806 |
| Spindler S and Reddy RG | Effect of pH on enzyme immunoassay and analysis of urine. | 1998 | Am Clin Lab | pmid:10345154 |
| Sauer LA et al. | 13-Hydroxyoctadecadienoic acid is the mitogenic signal for linoleic acid-dependent growth in rat hepatoma 7288CTC in vivo. | 1999 | Cancer Res. | pmid:10493526 |
| Blask DE et al. | Melatonin inhibition of cancer growth in vivo involves suppression of tumor fatty acid metabolism via melatonin receptor-mediated signal transduction events. | 1999 | Cancer Res. | pmid:10493527 |
| Sakashita T et al. | Essential involvement of 12-lipoxygenase in regiospecific andstereospecific oxidation of low density lipoprotein by macrophages. | 1999 | Eur. J. Biochem. | pmid:10504415 |
| Shureiqi I et al. | Decreased 13-S-hydroxyoctadecadienoic acid levels and 15-lipoxygenase-1 expression in human colon cancers. | 1999 | Carcinogenesis | pmid:10506115 |
| Chen NG et al. | PPARgamma agonists enhance human vascular endothelial adhesiveness by increasing ICAM-1 expression. | 1999 | Biochem. Biophys. Res. Commun. | pmid:10512746 |
| Blackburn ML et al. | Specific protein targets of 13-oxooctadecadienoic acid (13-OXO) and export of the 13-OXO-glutathione conjugate in HT-29 cells. | 1999 | Biochim. Biophys. Acta | pmid:10521706 |
| Dauchy RT et al. | Dim light during darkness stimulates tumor progression by enhancing tumor fatty acid uptake and metabolism. | 1999 | Cancer Lett. | pmid:10529012 |
| Jang MK et al. | Regulation of ferritin light chain gene expression by oxidized low-density lipoproteins in human monocytic THP-1 cells. | 1999 | Biochem. Biophys. Res. Commun. | pmid:10558912 |
| Ziboh VA et al. | Metabolism of polyunsaturated fatty acids by skin epidermal enzymes: generation of antiinflammatory and antiproliferative metabolites. | 2000 | Am. J. Clin. Nutr. | pmid:10617998 |
| Xi S et al. | Suppression of proto-oncogene (AP-1) in a model of skin epidermal hyperproliferation is reversed by topical application of 13-hydroxyoctadecadienoic acid and 15-hydroxyeicosatrienoic acid. | 2000 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10765974 |
| Bürger F et al. | Positional- and stereo-selectivity of fatty acid oxygenation catalysed by mouse (12S)-lipoxygenase isoenzymes. | 2000 | Biochem. J. | pmid:10816426 |
| Shureiqi I et al. | 15-LOX-1: a novel molecular target of nonsteroidal anti-inflammatory drug-induced apoptosis in colorectal cancer cells. | 2000 | J. Natl. Cancer Inst. | pmid:10904086 |
| Meilhac O et al. | Lipid peroxides induce expression of catalase in cultured vascular cells. | 2000 | J. Lipid Res. | pmid:10946007 |
| Han KH et al. | Oxidized LDL reduces monocyte CCR2 expression through pathways involving peroxisome proliferator-activated receptor gamma. | 2000 | J. Clin. Invest. | pmid:10995790 |
| Sauer LA et al. | Mechanism for the antitumor and anticachectic effects of n-3 fatty acids. | 2000 | Cancer Res. | pmid:11016660 |
| Ziboh VA et al. | Significance of lipoxygenase-derived monohydroxy fatty acids in cutaneous biology. | 2000 | Prostaglandins Other Lipid Mediat. | pmid:11104337 |
| Shureiqi I et al. | 15-Lipoxygenase-1 mediates nonsteroidal anti-inflammatory drug-induced apoptosis independently of cyclooxygenase-2 in colon cancer cells. | 2000 | Cancer Res. | pmid:11156377 |
| Dandona P et al. | The suppressive effect of dietary restriction and weight loss in the obese on the generation of reactive oxygen species by leukocytes, lipid peroxidation, and protein carbonylation. | 2001 | J. Clin. Endocrinol. Metab. | pmid:11232024 |
| Ek-Von Mentzer BA et al. | Binding of 13-HODE and 15-HETE to phospholipid bilayers, albumin, and intracellular fatty acid binding proteins. implications for transmembrane and intracellular transport and for protection from lipid peroxidation. | 2001 | J. Biol. Chem. | pmid:11278949 |
| Jude AR et al. | 13-hydroxy- and 13-oxooctadecadienoic acids: novel substrates for human UDP-glucuronosyltransferases. | 2001 | Drug Metab. Dispos. | pmid:11302930 |
| Azuma Y et al. | 15-Deoxy-delta(12,14)-prostaglandin J(2) inhibits IL-10 and IL-12 production by macrophages. | 2001 | Biochem. Biophys. Res. Commun. | pmid:11327705 |
| Shureiqi I et al. | Nonsteroidal anti-inflammatory drugs induce apoptosis in esophageal cancer cells by restoring 15-lipoxygenase-1 expression. | 2001 | Cancer Res. | pmid:11406566 |
| Aljada A et al. | Troglitazone reduces the expression of PPARgamma while stimulating that of PPARalpha in mononuclear cells in obese subjects. | 2001 | J. Clin. Endocrinol. Metab. | pmid:11443177 |
| Aljada A et al. | Nuclear factor-kappaB suppressive and inhibitor-kappaB stimulatory effects of troglitazone in obese patients with type 2 diabetes: evidence of an antiinflammatory action? | 2001 | J. Clin. Endocrinol. Metab. | pmid:11443197 |
| Hsi LC et al. | 15-lipoxygenase-1 metabolites down-regulate peroxisome proliferator-activated receptor gamma via the MAPK signaling pathway. | 2001 | J. Biol. Chem. | pmid:11447213 |
| Kim YS et al. | The orphan nuclear receptor small heterodimer partner as a novel coregulator of nuclear factor-kappa b in oxidized low density lipoprotein-treated macrophage cell line RAW 264.7. | 2001 | J. Biol. Chem. | pmid:11448950 |
| Kelavkar UP et al. | Overexpression of 15-lipoxygenase-1 in PC-3 human prostate cancer cells increases tumorigenesis. | 2001 | Carcinogenesis | pmid:11698337 |
| Jostarndt K et al. | Dissociation of apoptosis induction and CD36 upregulation by enzymatically modified low-density lipoprotein in monocytic cells. | 2002 | Biochem. Biophys. Res. Commun. | pmid:11798172 |
| Fischer B et al. | Dualism of oxidized lipoproteins in provoking and attenuating the oxidative burst in macrophages: role of peroxisome proliferator-activated receptor-gamma. | 2002 | J. Immunol. | pmid:11884452 |
| Schild RL et al. | The activity of PPAR gamma in primary human trophoblasts is enhanced by oxidized lipids. | 2002 | J. Clin. Endocrinol. Metab. | pmid:11889173 |
| Müller C et al. | Perturbation of lipid metabolism by linoleic acid hydroperoxide in CaCo-2 cells. | 2002 Mar-Apr | Biol. Chem. | pmid:12033453 |
| Askari B et al. | Oleate and linoleate enhance the growth-promoting effects of insulin-like growth factor-I through a phospholipase D-dependent pathway in arterial smooth muscle cells. | 2002 | J. Biol. Chem. | pmid:12138107 |
| Weichert H et al. | Metabolic profiling of oxylipins in germinating cucumber seedlings--lipoxygenase-dependent degradation of triacylglycerols and biosynthesis of volatile aldehydes. | 2002 | Planta | pmid:12172844 |
| Müller K et al. | Modulation of epidermal tumor development caused by targeted overexpression of epidermis-type 12S-lipoxygenase. | 2002 | Cancer Res. | pmid:12183416 |
| Hsi LC et al. | Opposing effects of 15-lipoxygenase-1 and -2 metabolites on MAPK signaling in prostate. Alteration in peroxisome proliferator-activated receptor gamma. | 2002 | J. Biol. Chem. | pmid:12189136 |
| Khan-Merchant N et al. | Oxidized fatty acids promote atherosclerosis only in the presence of dietary cholesterol in low-density lipoprotein receptor knockout mice. | 2002 | J. Nutr. | pmid:12421837 |
| Pasqualini ME et al. | Association between E-cadherin expression by human colon, bladder and breast cancer cells and the 13-HODE:15-HETE ratio. A possible role of their metastatic potential. | 2003 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:12538085 |
| Wu J et al. | 15-Lipoxygenase-1 mediates cyclooxygenase-2 inhibitor-induced apoptosis in gastric cancer. | 2003 | Carcinogenesis | pmid:12584173 |
| Nixon JB et al. | Evaluation of eicosanoids and NSAIDs as PPARgamma ligands in colorectal carcinoma cells. | 2003 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:12711249 |
| Hatley ME et al. | Increased production of 12/15 lipoxygenase eicosanoids accelerates monocyte/endothelial interactions in diabetic db/db mice. | 2003 | J. Biol. Chem. | pmid:12734208 |
| Akiba S et al. | Oxidized LDL activates phospholipase A2 to supply fatty acids required for cholesterol esterification. | 2003 | J. Lipid Res. | pmid:12777475 |
| Cho H et al. | Nonradiometric HPLC measurement of 13(S)-hydroxyoctadecadienoic acid from rat tissues. | 2003 | Anal. Biochem. | pmid:12782030 |
| Blask DE et al. | Growth and fatty acid metabolism of human breast cancer (MCF-7) xenografts in nude rats: impact of constant light-induced nocturnal melatonin suppression. | 2003 | Breast Cancer Res. Treat. | pmid:12846415 |
| Shureiqi I et al. | The 15-lipoxygenase-1 product 13-S-hydroxyoctadecadienoic acid down-regulates PPAR-delta to induce apoptosis in colorectal cancer cells. | 2003 | Proc. Natl. Acad. Sci. U.S.A. | pmid:12909723 |
| Buckley TL et al. | 13-hydroxyoctadecadienoic acid attenuates oedema formation induced by leukotriene B4 in vivo in rabbit skin. | 1992 | Eur. J. Pharmacol. | pmid:1330604 |
| De Meyer GR et al. | The role of endothelial cells in the relaxations induced by 13-hydroxy- and 13-hydroperoxylinoleic acid in canine arteries. | 1992 | Br. J. Pharmacol. | pmid:1422601 |
| Schade FU et al. | Lipoxygenase inhibitors but not site specific 5-lipoxygenase blockers protect against endotoxic shock and inhibit production of tumor necrosis factor. | 1992 | Eicosanoids | pmid:1449831 |
| Kandouz M et al. | Platelet-type 12-lipoxygenase activates NF-kappaB in prostate cancer cells. | 2003 | Prostaglandins Other Lipid Mediat. | pmid:14518561 |
| Nixon JB et al. | 15-Lipoxygenase-1 has anti-tumorigenic effects in colorectal cancer. | 2004 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:14643174 |
| Coutant F et al. | Sensing environmental lipids by dendritic cell modulates its function. | 2004 | J. Immunol. | pmid:14688309 |
| Blask DE et al. | Melatonin uptake and growth prevention in rat hepatoma 7288CTC in response to dietary melatonin: melatonin receptor-mediated inhibition of tumor linoleic acid metabolism to the growth signaling molecule 13-hydroxyoctadecadienoic acid and the potential role of phytomelatonin. | 2004 | Carcinogenesis | pmid:14754876 |
| Jostarndt K et al. | Enzymatically modified low-density lipoprotein upregulates CD36 in low-differentiated monocytic cells in a peroxisome proliferator-activated receptor-gamma-dependent way. | 2004 | Biochem. Pharmacol. | pmid:15104237 |
| Tanabe M et al. | Incorporation of arachidonic and linoleic acid hydroperoxides into cultured human umbilical vein endothelial cells. | 2004 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:15120710 |
| Dauchy RT et al. | Differential inhibition of fatty acid transport in tissue-isolated steroid receptor negative human breast cancer xenografts perfused in situ with isomers of conjugated linoleic acid. | 2004 | Cancer Lett. | pmid:15145516 |
| Lehmann WD et al. | Profiling assay for lipoxygenase products of linoleic and arachidonic acid by gas chromatography-mass spectrometry. | 1992 | Anal. Biochem. | pmid:1514683 |
| Schneider C et al. | Autoxidative transformation of chiral omega6 hydroxy linoleic and arachidonic acids to chiral 4-hydroxy-2E-nonenal. | 2004 | Chem. Res. Toxicol. | pmid:15257619 |
| Chechetkin IR et al. | The novel pathway for ketodiene oxylipin biosynthesis in Jerusalem artichoke (Helianthus tuberosus) tubers. | 2004 | Biochim. Biophys. Acta | pmid:15522817 |
| Akiba S et al. | Translocation of phospholipase A2 to membranes by oxidized LDL and hydroxyoctadecadienoic acid to contribute to cholesteryl ester formation. | 2004 | Biochim. Biophys. Acta | pmid:15522824 |
| Gerhardt B et al. | Lipoxygenase-mediated metabolism of storage lipids in germinating sunflower cotyledons and beta-oxidation of (9Z,11E,13S)-13-hydroxy-octadeca-9,11-dienoic acid by the cotyledonary glyoxysomes. | 2005 | Planta | pmid:15526214 |
| Hsi LC et al. | The histone deacetylase inhibitor suberoylanilide hydroxamic acid induces apoptosis via induction of 15-lipoxygenase-1 in colorectal cancer cells. | 2004 | Cancer Res. | pmid:15574791 |
| Hübke H et al. | Characterization and quantification of free and esterified 9- and 13-hydroxyoctadecadienoic acids (HODE) in barley, germinating barley, and finished malt. | 2005 | J. Agric. Food Chem. | pmid:15740040 |
| Manini P et al. | Free radical oxidation of coriolic acid (13-(S)-hydroxy-9Z,11E-octadecadienoic acid). | 2005 | Chem. Phys. Lipids | pmid:15784234 |
| Terao J et al. | Glutathione peroxidase mimics as novel antioxidants from vegetables. | 2005 | Biofactors | pmid:15817993 |
| Heslin MJ et al. | Tumor-associated down-regulation of 15-lipoxygenase-1 is reversed by celecoxib in colorectal cancer. | 2005 | Ann. Surg. | pmid:15912043 |
| Cho H et al. | Conjugated linoleic acid, cis-9,trans-11, is a substrate for pulmonary 15-lipoxygenase-1 in rat. | 2005 | J. Agric. Food Chem. | pmid:16131140 |
| Sauer LA et al. | Eicosapentaenoic acid suppresses cell proliferation in MCF-7 human breast cancer xenografts in nude rats via a pertussis toxin-sensitive signal transduction pathway. | 2005 | J. Nutr. | pmid:16140887 |
| Kim JS et al. | Overexpression of 15-lipoxygenase-1 induces growth arrest through phosphorylation of p53 in human colorectal cancer cells. | 2005 | Mol. Cancer Res. | pmid:16179498 |
| Kim JH et al. | Attenuation of breast tumor cell growth by conjugated linoleic acid via inhibition of 5-lipoxygenase activating protein. | 2005 | Biochim. Biophys. Acta | pmid:16185917 |
| Zuo X et al. | Oxidative metabolism of linoleic acid modulates PPAR-beta/delta suppression of PPAR-gamma activity. | 2006 | Oncogene | pmid:16288226 |
| Shureiqi I et al. | The critical role of 15-lipoxygenase-1 in colorectal epithelial cell terminal differentiation and tumorigenesis. | 2005 | Cancer Res. | pmid:16357157 |
| De Meyer GR et al. | Neointima formation impairs endothelial muscarinic receptors while enhancing prostacyclin-mediated responses in the rabbit carotid artery. | 1991 | Circ. Res. | pmid:1645234 |
| De Meyer GR et al. | Early atherosclerosis is accompanied by a decreased rather than an increased accumulation of fatty acid hydroxyderivatives. | 1991 | Biochem. Pharmacol. | pmid:1650207 |
| Engels F et al. | Production of arachidonic acid and linoleic acid metabolites by human bronchoalveolar lavage cells. | 1991 | Prostaglandins | pmid:1662406 |
| Seeley SK et al. | Metabolism of oxidized linoleic acid by glutathione transferases: peroxidase activity toward 13-hydroperoxyoctadecadienoic acid. | 2006 | Biochim. Biophys. Acta | pmid:16624487 |
| Hampel JK et al. | Differential modulation of cell cycle, apoptosis and PPARgamma2 gene expression by PPARgamma agonists ciglitazone and 9-hydroxyoctadecadienoic acid in monocytic cells. | 2006 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:16647253 |
| Chouinard S et al. | Isoform-specific regulation of uridine diphosphate-glucuronosyltransferase 2B enzymes in the human prostate: differential consequences for androgen and bioactive lipid inactivation. | 2006 | Endocrinology | pmid:16887906 |
| Buchanan MR et al. | Endothelial cell 13-HODE synthesis and tumor cell endothelial cell adhesion. | 1991 | Adv. Prostaglandin Thromboxane Leukot. Res. | pmid:1705085 |
| Buchanan MR et al. | 13-Hydroxyoctadecadienoic acid (13-HODE) metabolism and endothelial cell adhesion molecule expression: effect on platelet vessel wall adhesion. | 1991 | Wien. Klin. Wochenschr. | pmid:1718092 |
| Coleman JD et al. | The oxidative stress mediator 4-hydroxynonenal is an intracellular agonist of the nuclear receptor peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta). | 2007 | Free Radic. Biol. Med. | pmid:17382197 |
| Sauer LA et al. | Dietary factors and growth and metabolism in experimental tumors. | 2007 | J. Nutr. Biochem. | pmid:17418560 |
| Smith LC et al. | Dietary fish oil deactivates a growth-promoting signaling pathway in hepatoma 7288CTC in Buffalo rats. | 2006 | Nutr Cancer | pmid:17474866 |
| Yoshinaga M et al. | The 15-lipoxygenase-1 expression may enhance the sensitivity to non-steroidal anti-inflammatory drug-induced apoptosis in colorectal cancers from patients who are treated with the compounds. | 2007 | J. Gastroenterol. Hepatol. | pmid:17559385 |
| Altmann R et al. | 13-Oxo-ODE is an endogenous ligand for PPARgamma in human colonic epithelial cells. | 2007 | Biochem. Pharmacol. | pmid:17604003 |
| Dauchy RT et al. | Inhibition of fatty acid transport and proliferative activity in tissue-isolated human squamous cell cancer xenografts perfused in situ with melatonin or eicosapentaenoic or conjugated linoleic acids. | 2007 | Comp. Med. | pmid:17803052 |
| Wittwer J and Hersberger M | The two faces of the 15-lipoxygenase in atherosclerosis. | 2007 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:17869078 |
| Bastida E et al. | Effects of endothelial cell treatment on 13-HODE and prostacyclin synthesis and its correlation with tumor cell-vascular endothelial cell adhesion. | 1991 | Invasion Metastasis | pmid:1800451 |
| Liu B et al. | Lipoxygenase metabolites of arachidonic and linoleic acids modulate the adhesion of tumor cells to endothelium via regulation of protein kinase C. | 1991 | Cell Regul. | pmid:1801923 |
| Wang D et al. | Asymmetric dimethylarginine and lipid peroxidation products in early autosomal dominant polycystic kidney disease. | 2008 | Am. J. Kidney Dis. | pmid:18215696 |
| Brister SJ et al. | 13-HODE synthesis in internal mammary arteries and saphenous veins: implications in cardiovascular surgery. | 1991 | Adv. Prostaglandin Thromboxane Leukot. Res. | pmid:1825395 |
| Collins JF et al. | Induction of arachidonate 12-lipoxygenase (Alox15) in intestine of iron-deficient rats correlates with the production of biologically active lipid mediators. | 2008 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:18258795 |
| Manini P et al. | Biomimetic nitration of the linoleic acid metabolite 13-hydroxyoctadecadienoic acid: isolation and spectral characterization of novel chain-rearranged epoxy nitro derivatives. | 2008 | Chem. Phys. Lipids | pmid:18320610 |
| Tloti MA et al. | Effect of 13-hydroxyoctadeca-9,11-dienoic acid (13-HODE) on thrombin induced platelet adherence to endothelial cells in vitro. | 1991 | Thromb. Res. | pmid:1866713 |
| Wang D et al. | Asymmetric dimethylarginine, oxidative stress, and vascular nitric oxide synthase in essential hypertension. | 2009 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:18685064 |
| Melzig M and Scherke B | Effect of metabolites from linoleic acid on migratory behaviour of endothelial cells. | 1991 | Pharmazie | pmid:1886923 |