(+)-Catechin 3-Gallate

(+)-Catechin 3-Gallate is a lipid of Polyketides (PK) class. (+)-catechin 3-gallate is associated with abnormalities such as Epilepsy and Megalencephaly. The involved functions are known as Docking, Drug Interactions, inhibitors, Oxidation and Inflammation Process. (+)-catechin 3-gallate often locates in Solitary microtubule component of centriole or axonemal complex, Palmar surface, Glial and peritoneal. The associated genes with (+)-Catechin 3-Gallate are Homologous Gene and TSC1 gene.

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Introduction

To understand associated biological information of (+)-Catechin 3-Gallate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with (+)-Catechin 3-Gallate?

(+)-Catechin 3-Gallate is suspected in Epilepsy, Megalencephaly and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with (+)-Catechin 3-Gallate

MeSH term MeSH ID Detail
Cicatrix D002921 9 associated lipids
Total 1

PubChem Associated disorders and diseases

What pathways are associated with (+)-Catechin 3-Gallate

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with (+)-Catechin 3-Gallate?

Related references are published most in these journals:

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What functions are associated with (+)-Catechin 3-Gallate?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with (+)-Catechin 3-Gallate?

There are no associated biomedical information in the current reference collection.

What genes are associated with (+)-Catechin 3-Gallate?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with (+)-Catechin 3-Gallate?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with (+)-Catechin 3-Gallate

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Authors Title Published Journal PubMed Link
Kondo K et al. Mechanistic studies of catechins as antioxidants against radical oxidation. 1999 Arch. Biochem. Biophys. pmid:9917331
Paschka AG et al. Induction of apoptosis in prostate cancer cell lines by the green tea component, (-)-epigallocatechin-3-gallate. 1998 Cancer Lett. pmid:9751250
Kaneko T et al. Inhibition of linoleic acid hydroperoxide-induced toxicity in cultured human umbilical vein endothelial cells by catechins. 1998 Chem. Biol. Interact. pmid:9744559
Pietta PG et al. Catechin metabolites after intake of green tea infusions. 1998 Biofactors pmid:9699018
Kennedy DO et al. Involvement of protein tyrosine phosphorylation in the effect of green tea polyphenols on Ehrlich ascites tumor cells in vitro. 1998 Chem. Biol. Interact. pmid:9609384
Cishek MB et al. Effect of red wine on endothelium-dependent relaxation in rabbits. 1997 Clin. Sci. pmid:9497786
Zhang A et al. Inhibitory effects of jasmine green tea epicatechin isomers on free radical-induced lysis of red blood cells. 1997 Life Sci. pmid:9244364
Kuroda Y Bio-antimutagenic activity of green tea catechins in cultured Chinese hamster V79 cells. 1996 Mutat. Res. pmid:8980704
Matsumoto N et al. Inhibitory effects of tea catechins, black tea extract and oolong tea extract on hepatocarcinogenesis in rat. 1996 Jpn. J. Cancer Res. pmid:8957060
Yoshiki Y et al. Mechanism of catechin chemiluminescence in the presence of active oxygen. 1996 May-Jun J. Biolumin. Chemilumin. pmid:8844343
Sakanaka S et al. Inhibitory effects of green tea polyphenols on growth and cellular adherence of an oral bacterium, Porphyromonas gingivalis. 1996 Biosci. Biotechnol. Biochem. pmid:8704303
Isemura M et al. Effects of catechins on the mouse lung carcinoma cell adhesion to the endothelial cells. 1993 Cell Biol. Int. pmid:8348114
Terao J et al. Protective effect of epicatechin, epicatechin gallate, and quercetin on lipid peroxidation in phospholipid bilayers. 1994 Arch. Biochem. Biophys. pmid:8311465
Liao S and Hiipakka RA Selective inhibition of steroid 5 alpha-reductase isozymes by tea epicatechin-3-gallate and epigallocatechin-3-gallate. 1995 Biochem. Biophys. Res. Commun. pmid:7575552
Ogata K et al. Effects of catechins on the mouse tumor cell adhesion to fibronectin. 1995 Planta Med. pmid:7480211
Frost S et al. Characterization of Red Wine Proanthocyanidins Using a Putative Proanthocyanidin Database, Amide Hydrophilic Interaction Liquid Chromatography (HILIC), and Time-of-Flight Mass Spectrometry. 2018 Molecules pmid:30340402
Liu Q et al. Comparison of Antioxidant Activities of Different Grape Varieties. 2018 Molecules pmid:30249027
Kfoury N et al. Striking changes in tea metabolites due to elevational effects. 2018 Food Chem pmid:29853384
Al-Sayed E and Abdel-Daim MM Analgesic and anti-inflammatory activities of epicatechin gallate from Bauhinia hookeri. 2018 Drug Dev. Res. pmid:29732583
Park JE et al. Quantitative Analysis of Four Catechins from Green Tea Extract in Human Plasma Using Ultra-Performance Liquid Chromatography-Tandem Mass Spectrometry for Pharmacokinetic Studies. 2018 Molecules pmid:29690635
Xu YQ et al. Quantitative analyses of the bitterness and astringency of catechins from green tea. 2018 Food Chem pmid:29655718
Yang H et al. The relative antioxidant activity and steric structure of green tea catechins - A kinetic approach. 2018 Food Chem pmid:29622228
Tian DD et al. Identification of Intestinal UDP-Glucuronosyltransferase Inhibitors in Green Tea ( Using a Biochemometric Approach: Application to Raloxifene as a Test Drug via In Vitro to In Vivo Extrapolation. 2018 Drug Metab. Dispos. pmid:29467215
Stadlbauer S et al. Impact of Green Tea Catechin ECG and Its Synthesized Fluorinated Analogue on Prostate Cancer Cells and Stimulated Immunocompetent Cells. 2018 Planta Med. pmid:29466808
Mukherjee S et al. Liposomal TriCurin, A Synergistic Combination of Curcumin, Epicatechin Gallate and Resveratrol, Repolarizes Tumor-Associated Microglia/Macrophages, and Eliminates Glioblastoma (GBM) and GBM Stem Cells. 2018 Molecules pmid:29346317
Fujimaki T et al. Isolation of proanthocyanidins from red wine, and their inhibitory effects on melanin synthesis in vitro. 2018 Food Chem pmid:29329871
Satsu H et al. Suppressive effect of nobiletin and epicatechin gallate on fructose uptake in human intestinal epithelial Caco-2 cells. 2018 Biosci. Biotechnol. Biochem. pmid:29191128
Peng J et al. Separation and purification of four phenolic compounds from persimmon by high-speed counter-current chromatography. 2018 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:29136554
Yuan B et al. Extraction, identification, and quantification of antioxidant phenolics from hazelnut (Corylus avellana L.) shells. 2018 Food Chem pmid:29120806
Kim JH et al. Inhibitory activity of (-)-epicatechin-3,5-O-digallate on α-glucosidase and in silico analysis. 2018 Int. J. Biol. Macromol. pmid:28958819
Dhanani T et al. Extraction optimization of gallic acid, (+)-catechin, procyanidin-B2, (-)-epicatechin, (-)-epigallocatechin gallate, and (-)-epicatechin gallate: their simultaneous identification and quantification in Saraca asoca. 2017 J Food Drug Anal pmid:28911654
Zhu W et al. A-type ECG and EGCG dimers inhibit 3T3-L1 differentiation by binding to cholesterol in lipid rafts. 2017 J. Nutr. Biochem. pmid:28772148
Guo YJ et al. An integrated antioxidant activity fingerprint for commercial teas based on their capacities to scavenge reactive oxygen species. 2017 Food Chem pmid:28764047
Koch W et al. Catechin Composition and Antioxidant Activity of Black Teas in Relation to Brewing Time. 2017 J AOAC Int pmid:28707612
Karas D et al. Galloylation of polyphenols alters their biological activity. 2017 Food Chem. Toxicol. pmid:28428085
Zhang QA et al. Effect of ultrasound on the interaction between (-)-epicatechin gallate and bovine serum albumin in a model wine. 2017 Ultrason Sonochem pmid:28427650
Zhang Q et al. Metabolomics analysis reveals the metabolic and functional roles of flavonoids in light-sensitive tea leaves. 2017 BMC Plant Biol. pmid:28320327
Fan DM et al. Tea polyphenols dominate the short-term tea (Camellia sinensis) leaf litter decomposition. 2017 Feb. J Zhejiang Univ Sci B pmid:28124839
Cui L et al. Extraction of Epigallocatechin Gallate and Epicatechin Gallate from Tea Leaves Using β-Cyclodextrin. 2017 J. Food Sci. pmid:28071811
Farhan M et al. Mobilization of Nuclear Copper by Green Tea Polyphenol Epicatechin-3-Gallate and Subsequent Prooxidant Breakage of Cellular DNA: Implications for Cancer Chemotherapy. 2016 Int J Mol Sci pmid:28035959
Lei S et al. Effective synthesis of theaflavin-3,3'-digallate with epigallocatechin-3-O-gallate and epicatechin gallate as substrates by using immobilized pear polyphenol oxidase. 2017 Int. J. Biol. Macromol. pmid:27780760
Wein S et al. Systemic Absorption of Catechins after Intraruminal or Intraduodenal Application of a Green Tea Extract in Cows. 2016 PLoS ONE pmid:27427946
Chen JH et al. Autophagic effects of Hibiscus sabdariffa leaf polyphenols and epicatechin gallate (ECG) against oxidized LDL-induced injury of human endothelial cells. 2017 Eur J Nutr pmid:27318926
Kobayashi K et al. Strong Inhibition of Secretory Sphingomyelinase by Catechins, Particularly by (-)-Epicatechin 3-O-Gallate and (-)-3'-O-Methylepigallocatechin 3-O-Gallate. 2016 J. Nutr. Sci. Vitaminol. pmid:27264097
Malik S et al. Molecular mechanisms underlying attenuation of cisplatin-induced acute kidney injury by epicatechin gallate. 2016 Lab. Invest. pmid:27239733
Huang SF et al. Epicatechin-3-gallate reverses TGF-β1-induced epithelial-to-mesenchymal transition and inhibits cell invasion and protease activities in human lung cancer cells. 2016 Food Chem. Toxicol. pmid:27224248
Fathima A and Rao JR Selective toxicity of Catechin-a natural flavonoid towards bacteria. 2016 Appl. Microbiol. Biotechnol. pmid:27052380
Afsar T et al. Growth inhibition and apoptosis in cancer cells induced by polyphenolic compounds of Acacia hydaspica: Involvement of multiple signal transduction pathways. 2016 Sci Rep pmid:26975752
Takechi R et al. Elevated plasma and urinary concentrations of green tea catechins associated with improved plasma lipid profile in healthy Japanese women. 2016 Nutr Res pmid:26923508
Chiou YS et al. Directly interact with Keap1 and LPS is involved in the anti-inflammatory mechanisms of (-)-epicatechin-3-gallate in LPS-induced macrophages and endotoxemia. 2016 Free Radic. Biol. Med. pmid:26878775
Godsey J and Grundmann O Review of Various Herbal Supplements as Complementary Treatments for Oral Cancer. 2016 J Diet Suppl pmid:26863913
Ujihara T and Hayashi N Association of Catechin Molecules in Water: Quantitative Binding Study and Complex Structure Analysis. 2016 J. Nat. Prod. pmid:26720794
Zinellu A et al. N- and S-homocysteinylation reduce the binding of human serum albumin to catechins. 2017 Eur J Nutr pmid:26658763
Li Q et al. Separation and characterization of polyphenolics from underutilized byproducts of fruit production (Choerospondias axillaris peels): inhibitory activity of proanthocyanidins against glycolysis enzymes. 2015 Food Funct pmid:26442714
Grases F et al. Effect of consuming a grape seed supplement with abundant phenolic compounds on the oxidative status of healthy human volunteers. 2015 Nutr J pmid:26353756
Zhang YN et al. Improving the sweet aftertaste of green tea infusion with tannase. 2016 Food Chem pmid:26304374
Rosado H et al. Impact of the β-Lactam Resistance Modifier (-)-Epicatechin Gallate on the Non-Random Distribution of Phospholipids across the Cytoplasmic Membrane of Staphylococcus aureus. 2015 Int J Mol Sci pmid:26213914
Lall N et al. Extract from Ceratonia siliqua Exhibits Depigmentation Properties. 2015 Phytother Res pmid:26201055
Zhu W et al. A-type ECG and EGCG dimers disturb the structure of 3T3-L1 cell membrane and strongly inhibit its differentiation by targeting peroxisome proliferator-activated receptor γ with miR-27 involved mechanism. 2015 J. Nutr. Biochem. pmid:26145192
Cai Y et al. (-)-Epicatechin-3-gallate (a polyphenol from green tea) potentiates doxorubicin-induced apoptosis in H9C2 cardiomyocytes. 2015 Biotechnol. Lett. pmid:26063620
Zhang B et al. Inflammatory mechanisms contribute to the neurological manifestations of tuberous sclerosis complex. 2015 Neurobiol. Dis. pmid:26003087
Miao M et al. Interaction mechanism between green tea extract and human α-amylase for reducing starch digestion. 2015 Food Chem pmid:25976786
Liu Y et al. Molecular weight and galloylation affect grape seed extract constituents' ability to cross-link dentin collagen in clinically relevant time. 2015 Dent Mater pmid:25958268
Müller P and Downard KM Catechin inhibition of influenza neuraminidase and its molecular basis with mass spectrometry. 2015 J Pharm Biomed Anal pmid:25910046
Schmuch J et al. Extract from Rumex acetosa L. for prophylaxis of periodontitis: inhibition of bacterial in vitro adhesion and of gingipains of Porphyromonas gingivalis by epicatechin-3-O-(4β→8)-epicatechin-3-O-gallate (procyanidin-B2-Di-gallate). 2015 PLoS ONE pmid:25803708
Kaneko YK et al. Structure-dependent inhibitory effects of green tea catechins on insulin secretion from pancreatic β-cells. 2015 Biol. Pharm. Bull. pmid:25757931
Chen L et al. Bioactivity-guided fractionation of an antidiarrheal Chinese herb Rhodiola kirilowii (Regel) Maxim reveals (-)-epicatechin-3-gallate and (-)-epigallocatechin-3-gallate as inhibitors of cystic fibrosis transmembrane conductance regulator. 2015 PLoS ONE pmid:25747701
Chiu CT et al. Hibiscus sabdariffa leaf polyphenolic extract induces human melanoma cell death, apoptosis, and autophagy. 2015 J. Food Sci. pmid:25694272
Perumal S et al. Anti-infective potential of caffeic acid and epicatechin 3-gallate isolated from methanol extract of Euphorbia hirta (L.) against Pseudomonas aeruginosa. 2015 Nat. Prod. Res. pmid:25571920
Zhu YT et al. Fast identification of lipase inhibitors in oolong tea by using lipase functionalised Fe3O4 magnetic nanoparticles coupled with UPLC-MS/MS. 2015 Food Chem pmid:25466054
Song BJ et al. Thermal degradation of green tea flavan-3-ols and formation of hetero- and homocatechin dimers in model dairy beverages. 2015 Food Chem pmid:25466027
Barr JT et al. Inhibition of human aldehyde oxidase activity by diet-derived constituents: structural influence, enzyme-ligand interactions, and clinical relevance. 2015 Drug Metab. Dispos. pmid:25326286
Abourashed EA et al. Content Variation of Catechin Markers, Total Phenolics and Caffeine in Green Tea Dietary Supplements. 2016 J Diet Suppl pmid:25299974
Ando T et al. Effects of tea catechins on cholesterol absorption with exogenously hypercholesterolemic rat (ExHC-Ta). 1989 Bull Kanagawa Dent Coll pmid:2519221
Tay PY et al. Assessment of extraction parameters on antioxidant capacity, polyphenol content, epigallocatechin gallate (EGCG), epicatechin gallate (ECG) and iriflophenone 3-C-β-glucoside of agarwood (Aquilaria crassna) young leaves. 2014 Molecules pmid:25153858
Furlan AL et al. Membrane lipids protected from oxidation by red wine tannins: a proton NMR study. 2014 Biochimie pmid:25063276
Pal S et al. Inhibition of catalase by tea catechins in free and cellular state: a biophysical approach. 2014 PLoS ONE pmid:25025898
Lee LS et al. Quantitative analysis of major constituents in green tea with different plucking periods and their antioxidant activity. 2014 Molecules pmid:24988187
Paulin S et al. Surfactant-free purification of membrane protein complexes from bacteria: application to the staphylococcal penicillin-binding protein complex PBP2/PBP2a. 2014 Nanotechnology pmid:24972373
Ge H et al. Mechanistic studies for tri-targeted inhibition of enzymes involved in cholesterol biosynthesis by green tea polyphenols. 2014 Org. Biomol. Chem. pmid:24879560
Nakanishi T et al. Catechins inhibit vascular endothelial growth factor production and cyclooxygenase-2 expression in human dental pulp cells. 2015 Int Endod J pmid:24847951
Lakornwong W et al. Chemical constituents from the roots of Leea thorelii Gagnep. 2014 Nat. Prod. Res. pmid:24784484
Zhang Y et al. [Assessment of inner filter effect corrections in fluorimetry of the interaction between polyphenols and proteins]. 2014 Guang Pu Xue Yu Guang Pu Fen Xi pmid:24783545
Roland WS et al. 6-methoxyflavanones as bitter taste receptor blockers for hTAS2R39. 2014 PLoS ONE pmid:24722342
Stavniichuk R et al. Peroxynitrite and protein nitration in the pathogenesis of diabetic peripheral neuropathy. 2014 Diabetes Metab. Res. Rev. pmid:24687457
Siddique YH et al. Effect of epicatechin gallate dietary supplementation on transgenic Drosophila model of Parkinson's disease. 2014 J Diet Suppl pmid:24670116
Peek J et al. Identification of Novel Polyphenolic Inhibitors of Shikimate Dehydrogenase (AroE). 2014 J Biomol Screen pmid:24632659
Byun MR et al. (-)-Epicatechin gallate (ECG) stimulates osteoblast differentiation via Runt-related transcription factor 2 (RUNX2) and transcriptional coactivator with PDZ-binding motif (TAZ)-mediated transcriptional activation. 2014 J. Biol. Chem. pmid:24515112
Yousaf S et al. The role of green tea extract and powder in mitigating metabolic syndromes with special reference to hyperglycemia and hypercholesterolemia. 2014 Food Funct pmid:24473227
Narumi K et al. Simultaneous detection of green tea catechins and gallic acid in human serum after ingestion of green tea tablets using ion-pair high-performance liquid chromatography with electrochemical detection. 2014 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:24342507
Roman MC Determination of catechins and caffeine in camillia sinensis raw materials, extracts, and dietary supplements by HPLC-uv: single-laboratory validation. 2013 Sep-Oct J AOAC Int pmid:24282928
Naldi M et al. UHPLC determination of catechins for the quality control of green tea. 2014 J Pharm Biomed Anal pmid:24103292
Yamazaki T et al. Activation of the hTAS2R14 human bitter-taste receptor by (-)-epigallocatechin gallate and (-)-epicatechin gallate. 2013 Biosci. Biotechnol. Biochem. pmid:24018685
Bourassa P et al. The effect of milk alpha-casein on the antioxidant activity of tea polyphenols. 2013 J. Photochem. Photobiol. B, Biol. pmid:24001682
Vogiatzoglou A et al. Estimated dietary intakes and sources of flavanols in the German population (German National Nutrition Survey II). 2014 Eur J Nutr pmid:23917449
Zhang Y et al. Interaction of characteristic structural elements of persimmon tannin with Chinese cobra PLA2. 2013 Toxicon pmid:23916601
Cordero-Herrera I et al. Epicatechin gallate induces cell death via p53 activation and stimulation of p38 and JNK in human colon cancer SW480 cells. 2013 Nutr Cancer pmid:23859040
Ly BT et al. Inhibition of FLT3 expression by green tea catechins in FLT3 mutated-AML cells. 2013 PLoS ONE pmid:23840454
Li F et al. Inhibitory effect of catechin-related compounds on renin activity. 2013 Biomed. Res. pmid:23782751
Shin SY et al. Chromenylchalcones showing cytotoxicity on human colon cancer cell lines and in silico docking with aurora kinases. 2013 Bioorg. Med. Chem. pmid:23719279