MeSH term | MeSH ID | Detail |
---|---|---|
Cicatrix | D002921 | 9 associated lipids |
(+)-Catechin 3-Gallate is a lipid of Polyketides (PK) class. (+)-catechin 3-gallate is associated with abnormalities such as Epilepsy and Megalencephaly. The involved functions are known as Docking, Drug Interactions, inhibitors, Oxidation and Inflammation Process. (+)-catechin 3-gallate often locates in Solitary microtubule component of centriole or axonemal complex, Palmar surface, Glial and peritoneal. The associated genes with (+)-Catechin 3-Gallate are Homologous Gene and TSC1 gene.
To understand associated biological information of (+)-Catechin 3-Gallate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
(+)-Catechin 3-Gallate is suspected in Epilepsy, Megalencephaly and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with (+)-Catechin 3-Gallate
MeSH term | MeSH ID | Detail |
---|---|---|
Cicatrix | D002921 | 9 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
pmid: | ||||
Okushio K et al. | Methylation of tea catechins by rat liver homogenates. | 1999 | Biosci. Biotechnol. Biochem. | pmid:10192923 |
Kondo K et al. | Scavenging mechanisms of (-)-epigallocatechin gallate and (-)-epicatechin gallate on peroxyl radicals and formation of superoxide during the inhibitory action. | 1999 | Free Radic. Biol. Med. | pmid:10515590 |
Fulcrand H et al. | Study of wine tannin oligomers by on-line liquid chromatography electrospray ionization mass spectrometry. | 1999 | J. Agric. Food Chem. | pmid:10552410 |
Nanjo F et al. | Radical scavenging activity of tea catechins and their related compounds. | 1999 | Biosci. Biotechnol. Biochem. | pmid:10610125 |
Bors W and Michel C | Antioxidant capacity of flavanols and gallate esters: pulse radiolysis studies. | 1999 | Free Radic. Biol. Med. | pmid:10641736 |
Van Dyke K et al. | Green tea extract and its polyphenols markedly inhibit luminol-dependent chemiluminescence activated by peroxynitrite or SIN-1. | 2000 Jan-Feb | Luminescence | pmid:10660664 |
Bors W et al. | Electron paramagnetic resonance studies of radical species of proanthocyanidins and gallate esters. | 2000 | Arch. Biochem. Biophys. | pmid:10666317 |
Maeda-Yamamoto M et al. | Effects of tea polyphenols on the invasion and matrix metalloproteinases activities of human fibrosarcoma HT1080 cells. | 1999 | J. Agric. Food Chem. | pmid:10794635 |
Mukhtar H and Ahmad N | Tea polyphenols: prevention of cancer and optimizing health. | 2000 | Am. J. Clin. Nutr. | pmid:10837321 |
Shi X et al. | Antioxidant properties of (-)-epicatechin-3-gallate and its inhibition of Cr(VI)-induced DNA damage and Cr(IV)- or TPA-stimulated NF-kappaB activation. | 2000 | Mol. Cell. Biochem. | pmid:10839202 |
Liu Z et al. | Antioxidative effects of green tea polyphenols on free radical initiated and photosensitized peroxidation of human low density lipoprotein. | 2000 | Chem. Phys. Lipids | pmid:10878235 |
Zhu M et al. | Oral absorption and bioavailability of tea catechins. | 2000 | Planta Med. | pmid:10909265 |
Yang B et al. | Determination of catechins in human urine subsequent to tea ingestion by high-performance liquid chromatography with electrochemical detection. | 2000 | Anal. Biochem. | pmid:10929811 |
Tan X et al. | Differences of four catechins in cell cycle arrest and induction of apoptosis in LoVo cells. | 2000 | Cancer Lett. | pmid:10940502 |
Lotito SB and Fraga CG | Catechins delay lipid oxidation and alpha-tocopherol and beta-carotene depletion following ascorbate depletion in human plasma. | 2000 | Proc. Soc. Exp. Biol. Med. | pmid:10998196 |
Kobayashi Y et al. | Green tea polyphenols inhibit the sodium-dependent glucose transporter of intestinal epithelial cells by a competitive mechanism. | 2000 | J. Agric. Food Chem. | pmid:11087528 |
Chen Z et al. | Degradation of green tea catechins in tea drinks. | 2001 | J. Agric. Food Chem. | pmid:11170614 |
Crouvezier S et al. | The effects of phenolic components of tea on the production of pro- and anti-inflammatory cytokines by human leukocytes in vitro. | 2001 | Cytokine | pmid:11243706 |
Tsuchiya H | Stereospecificity in membrane effects of catechins. | 2001 | Chem. Biol. Interact. | pmid:11248221 |
de Freitas V and Mateus N | Structural features of procyanidin interactions with salivary proteins. | 2001 | J. Agric. Food Chem. | pmid:11262053 |
Zhu M et al. | Pharmacokinetics and system linearity of tea catechins in rat. | 2001 | Xenobiotica | pmid:11334265 |
Muto S et al. | Inhibition by green tea catechins of metabolic activation of procarcinogens by human cytochrome P450. | 2001 | Mutat. Res. | pmid:11470492 |
Chen ZY et al. | Inhibitory effects of purified green tea epicatechins on contraction and proliferation of arterial smooth muscle cells. | 2000 | Acta Pharmacol. Sin. | pmid:11501167 |
Kim JH et al. | Prolyl endopeptidase inhibitors from green tea. | 2001 | Arch. Pharm. Res. | pmid:11534759 |
Tillekeratne LM et al. | Simplified catechin-gallate inhibitors of HIV-1 reverse transcriptase. | 2001 | Bioorg. Med. Chem. Lett. | pmid:11591519 |
Hong J et al. | Effects of purified green and black tea polyphenols on cyclooxygenase- and lipoxygenase-dependent metabolism of arachidonic acid in human colon mucosa and colon tumor tissues. | 2001 | Biochem. Pharmacol. | pmid:11705450 |
Pan CY et al. | Enhancement of inward Ca(2+) currents in bovine chromaffin cells by green tea polyphenol extracts. | 2002 | Neurochem. Int. | pmid:11738479 |
Van Amelsvoort JM et al. | Plasma concentrations of individual tea catechins after a single oral dose in humans. | 2001 | Xenobiotica | pmid:11780763 |
Lamy S et al. | Green tea catechins inhibit vascular endothelial growth factor receptor phosphorylation. | 2002 | Cancer Res. | pmid:11809684 |
Mochizuki M et al. | Kinetic analysis and mechanistic aspects of autoxidation of catechins. | 2002 | Biochim. Biophys. Acta | pmid:11853955 |
Nakagawa T et al. | Protective activity of green tea against free radical- and glucose-mediated protein damage. | 2002 | J. Agric. Food Chem. | pmid:11929306 |
Sartippour MR et al. | Green tea and its catechins inhibit breast cancer xenografts. | 2001 | Nutr Cancer | pmid:11962250 |
Waffo-Téguo P et al. | Potential cancer-chemopreventive activities of wine stilbenoids and flavans extracted from grape (Vitis vinifera) cell cultures. | 2001 | Nutr Cancer | pmid:11962253 |
Amantana A et al. | Antimutagenic activity of selenium-enriched green tea toward the heterocyclic amine 2-amino-3-methylimidazo[4,5-f]quinoline. | 2002 | Biol Trace Elem Res | pmid:12008980 |
Sachinidis A et al. | Inhibition of the PDGF beta-receptor tyrosine phosphorylation and its downstream intracellular signal transduction pathway in rat and human vascular smooth muscle cells by different catechins. | 2002 | FASEB J. | pmid:12039871 |
Hossain SJ et al. | Effects of tea components on the response of GABA(A) receptors expressed in Xenopus Oocytes. | 2002 | J. Agric. Food Chem. | pmid:12083865 |
Sarni-Manchado P and Cheynier V | Study of non-covalent complexation between catechin derivatives and peptides by electrospray ionization mass spectrometry. | 2002 | J Mass Spectrom | pmid:12112743 |
Hossain SJ et al. | Polyphenol-induced inhibition of the response of na(+)/glucose cotransporter expressed in Xenopus oocytes. | 2002 | J. Agric. Food Chem. | pmid:12188632 |
Nagaoka H et al. | Spectrofluorometric determination of catechins with 1,2-diphenylethylenediamine. | 2002 | Anal Sci | pmid:12200848 |
Murakami C et al. | Effect of tea catechins on cellular lipid peroxidation and cytotoxicity in HepG2 cells. | 2002 | Biosci. Biotechnol. Biochem. | pmid:12224642 |
Nakagawa T and Yokozawa T | Direct scavenging of nitric oxide and superoxide by green tea. | 2002 | Food Chem. Toxicol. | pmid:12419687 |
Saito M et al. | Green tea polyphenols inhibit metalloproteinase activities in the skin, muscle, and blood of rainbow trout. | 2002 | J. Agric. Food Chem. | pmid:12428978 |
Anderson RA and Polansky MM | Tea enhances insulin activity. | 2002 | J. Agric. Food Chem. | pmid:12428980 |
Caturla N et al. | The relationship between the antioxidant and the antibacterial properties of galloylated catechins and the structure of phospholipid model membranes. | 2003 | Free Radic. Biol. Med. | pmid:12633742 |
Sakanaka S | A novel convenient process to obtain a raw decaffeinated tea polyphenol fraction using a lignocellulose column. | 2003 | J. Agric. Food Chem. | pmid:12720405 |
Takizawa Y et al. | Pharmacokinetics of (-)-epicatechin-3-O-gallate, an active component of Onpi-to, in rats. | 2003 | Biol. Pharm. Bull. | pmid:12736498 |
Morré DJ et al. | Tea catechin synergies in inhibition of cancer cell proliferation and of a cancer specific cell surface oxidase (ECTO-NOX). | 2003 | Pharmacol. Toxicol. | pmid:12753411 |
Vankemmelbeke MN et al. | Selective inhibition of ADAMTS-1, -4 and -5 by catechin gallate esters. | 2003 | Eur. J. Biochem. | pmid:12755694 |
Moore PS and Pizza C | Observations on the inhibition of HIV-1 reverse transcriptase by catechins. | 1992 | Biochem. J. | pmid:1281981 |
Kohri T et al. | Identification of metabolites of (-)-epicatechin gallate and their metabolic fate in the rat. | 2003 | J. Agric. Food Chem. | pmid:12926915 |
Vaidyanathan JB and Walle T | Cellular uptake and efflux of the tea flavonoid (-)epicatechin-3-gallate in the human intestinal cell line Caco-2. | 2003 | J. Pharmacol. Exp. Ther. | pmid:12970388 |
Chen L et al. | Tea catechins protect against lead-induced ROS formation, mitochondrial dysfunction, and calcium dysregulation in PC12 cells. | 2003 | Chem. Res. Toxicol. | pmid:12971804 |
Wang X et al. | The galloyl moiety of green tea catechins is the critical structural feature to inhibit fatty-acid synthase. | 2003 | Biochem. Pharmacol. | pmid:14599562 |
Goodin MG and Rosengren RJ | Epigallocatechin gallate modulates CYP450 isoforms in the female Swiss-Webster mouse. | 2003 | Toxicol. Sci. | pmid:14600287 |
Konishi Y et al. | Tea polyphenols inhibit the transport of dietary phenolic acids mediated by the monocarboxylic acid transporter (MCT) in intestinal Caco-2 cell monolayers. | 2003 | J. Agric. Food Chem. | pmid:14640574 |
Ikeda I et al. | Heat-epimerized tea catechins rich in gallocatechin gallate and catechin gallate are more effective to inhibit cholesterol absorption than tea catechins rich in epigallocatechin gallate and epicatechin gallate. | 2003 | J. Agric. Food Chem. | pmid:14640575 |
Kaszkin M et al. | Unravelling green tea's mechanisms of action: more than meets the eye. | 2004 | Mol. Pharmacol. | pmid:14722232 |
Okamoto M et al. | Inhibitory effect of green tea catechins on cysteine proteinases in Porphyromonas gingivalis. | 2004 | Oral Microbiol. Immunol. | pmid:14871352 |
Arakawa H et al. | Role of hydrogen peroxide in bactericidal action of catechin. | 2004 | Biol. Pharm. Bull. | pmid:14993788 |
Yokozawa T et al. | (-)-Epicatechin 3-O-gallate ameliorates the damages related to peroxynitrite production by mechanisms distinct from those of other free radical inhibitors. | 2004 | J. Pharm. Pharmacol. | pmid:15005882 |
Zhong Z et al. | Polyphenols from Camellia sinenesis prevent primary graft failure after transplantation of ethanol-induced fatty livers from rats. | 2004 | Free Radic. Biol. Med. | pmid:15110390 |
Stapleton PD et al. | Modulation of beta-lactam resistance in Staphylococcus aureus by catechins and gallates. | 2004 | Int. J. Antimicrob. Agents | pmid:15120724 |
Wan SB et al. | Study of the green tea polyphenols catechin-3-gallate (CG) and epicatechin-3-gallate (ECG) as proteasome inhibitors. | 2004 | Bioorg. Med. Chem. | pmid:15186836 |
Kapoor M et al. | Effects of epicatechin gallate on wound healing and scar formation in a full thickness incisional wound healing model in rats. | 2004 | Am. J. Pathol. | pmid:15215184 |
Chen L et al. | Effect of tea catechins on the change of glutathione levels caused by Pb(++) in PC12 cells. | 2004 | Chem. Res. Toxicol. | pmid:15257617 |
Galvez Peralta J et al. | (-)-Epicatechin-3-galloyl ester: a secretagogue compound from the bark of Sclerocarya birrea. | 1992 | Planta Med. | pmid:1529030 |
Baek SJ et al. | Epicatechin gallate-induced expression of NAG-1 is associated with growth inhibition and apoptosis in colon cancer cells. | 2004 | Carcinogenesis | pmid:15308587 |
Chu KO et al. | Determination of catechins and catechin gallates in tissues by liquid chromatography with coulometric array detection and selective solid phase extraction. | 2004 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:15380714 |
Hayakawa F et al. | Prooxidative activities of tea catechins in the presence of Cu2+. | 2004 | Biosci. Biotechnol. Biochem. | pmid:15388955 |
Strobel P et al. | Myricetin, quercetin and catechin-gallate inhibit glucose uptake in isolated rat adipocytes. | 2005 | Biochem. J. | pmid:15469417 |
Zhang L et al. | Investigation of intestinal absorption and disposition of green tea catechins by Caco-2 monolayer model. | 2004 | Int J Pharm | pmid:15541906 |
Joiner A et al. | Ellipsometry analysis of the in vitro adsorption of tea polyphenols onto salivary pellicles. | 2004 | Eur. J. Oral Sci. | pmid:15560834 |
Legssyer A et al. | Tannins and catechin gallate mediate the vasorelaxant effect of Arbutus unedo on the rat isolated aorta. | 2004 | Phytother Res | pmid:15597331 |
Taniguchi S et al. | Inhibition of heparin-induced tau filament formation by phenothiazines, polyphenols, and porphyrins. | 2005 | J. Biol. Chem. | pmid:15611092 |
Zhou YD et al. | Hypoxia-inducible factor-1 activation by (-)-epicatechin gallate: potential adverse effects of cancer chemoprevention with high-dose green tea extracts. | 2004 | J. Nat. Prod. | pmid:15620252 |
Crespy V et al. | Glucuronidation of the green tea catechins, (-)-epigallocatechin-3-gallate and (-)-epicatechin-3-gallate, by rat hepatic and intestinal microsomes. | 2004 | Free Radic. Res. | pmid:15621722 |
Fujimura Y et al. | A difference between epigallocatechin-3-gallate and epicatechin-3-gallate on anti-allergic effect is dependent on their distinct distribution to lipid rafts. | 2004 | Biofactors | pmid:15630184 |
Gibbons S et al. | Catechin gallates inhibit multidrug resistance (MDR) in Staphylococcus aureus. | 2004 | Planta Med. | pmid:15643566 |
Babich H et al. | Differential in vitro cytotoxicity of (-)-epicatechin gallate (ECG) to cancer and normal cells from the human oral cavity. | 2005 | Toxicol In Vitro | pmid:15649637 |
Ikeda I et al. | Tea catechins with a galloyl moiety suppress postprandial hypertriacylglycerolemia by delaying lymphatic transport of dietary fat in rats. | 2005 | J. Nutr. | pmid:15671206 |
Huang CC et al. | Protective effects of (-)-epicatechin-3-gallate on UVA-induced damage in HaCaT keratinocytes. | 2005 | Arch. Dermatol. Res. | pmid:15726391 |
Mukai K et al. | Structure-activity relationship of the tocopherol-regeneration reaction by catechins. | 2005 | Free Radic. Biol. Med. | pmid:15808422 |
Feucht W et al. | Flavanols in somatic cell division and male meiosis of tea (Camellia sinensis) anthers. | 2005 | Plant Biol (Stuttg) | pmid:15822012 |
Liu S et al. | Theaflavin derivatives in black tea and catechin derivatives in green tea inhibit HIV-1 entry by targeting gp41. | 2005 | Biochim. Biophys. Acta | pmid:15823507 |
Chen D et al. | Inhibition of human liver catechol-O-methyltransferase by tea catechins and their metabolites: structure-activity relationship and molecular-modeling studies. | 2005 | Biochem. Pharmacol. | pmid:15857617 |
Anderson JC et al. | Synthesis and antibacterial activity of hydrolytically stable (-)-epicatechin gallate analogues for the modulation of beta-lactam resistance in Staphylococcus aureus. | 2005 | Bioorg. Med. Chem. Lett. | pmid:15863332 |
El Bedoui J et al. | Catechins prevent vascular smooth muscle cell invasion by inhibiting MT1-MMP activity and MMP-2 expression. | 2005 | Cardiovasc. Res. | pmid:15885676 |
Anger DL et al. | Heteroactivation of cytochrome P450 1A1 by teas and tea polyphenols. | 2005 | Br. J. Pharmacol. | pmid:15895106 |
Navarro-Perán E et al. | Kinetics of the inhibition of bovine liver dihydrofolate reductase by tea catechins: origin of slow-binding inhibition and pH studies. | 2005 | Biochemistry | pmid:15895994 |
Ikeda I et al. | Dietary gallate esters of tea catechins reduce deposition of visceral fat, hepatic triacylglycerol, and activities of hepatic enzymes related to fatty acid synthesis in rats. | 2005 | Biosci. Biotechnol. Biochem. | pmid:15914933 |
Yamazaki T et al. | Biosynthesized tea polyphenols inactivate Chlamydia trachomatis in vitro. | 2005 | Antimicrob. Agents Chemother. | pmid:15917555 |
Zhang R et al. | Novel inhibitors of fatty-acid synthase from green tea (Camellia sinensis Xihu Longjing) with high activity and a new reacting site. | 2006 | Biotechnol. Appl. Biochem. | pmid:15943584 |
Yao L et al. | Seasonal variations of phenolic compounds in Australia-grown tea (Camellia sinensis). | 2005 | J. Agric. Food Chem. | pmid:16076137 |
Kumar NS and Rajapaksha M | Separation of catechin constituents from five tea cultivars using high-speed counter-current chromatography. | 2005 | J Chromatogr A | pmid:16078712 |
Kadowaki M et al. | Inhibitory effects of catechin gallates on o-methyltranslation of protocatechuic acid in rat liver cytosolic preparations and cultured hepatocytes. | 2005 | Biol. Pharm. Bull. | pmid:16079503 |
Mukai K et al. | Kinetic study of the quenching reaction of singlet oxygen by tea catechins in ethanol solution. | 2005 | Free Radic. Biol. Med. | pmid:16109305 |
Tsang C et al. | The absorption, metabolism and excretion of flavan-3-ols and procyanidins following the ingestion of a grape seed extract by rats. | 2005 | Br. J. Nutr. | pmid:16115350 |
Song JM et al. | Antiviral effect of catechins in green tea on influenza virus. | 2005 | Antiviral Res. | pmid:16137775 |
Nakamuta M et al. | Epigallocatechin-3-gallate, a polyphenol component of green tea, suppresses both collagen production and collagenase activity in hepatic stellate cells. | 2005 | Int. J. Mol. Med. | pmid:16142404 |