| MeSH term | MeSH ID | Detail |
|---|---|---|
| Cicatrix | D002921 | 9 associated lipids |
Total
1
(+)-Catechin 3-Gallate
(+)-Catechin 3-Gallate is a lipid of Polyketides (PK) class. (+)-catechin 3-gallate is associated with abnormalities such as Epilepsy and Megalencephaly. The involved functions are known as Docking, Drug Interactions, inhibitors, Oxidation and Inflammation Process. (+)-catechin 3-gallate often locates in Solitary microtubule component of centriole or axonemal complex, Palmar surface, Glial and peritoneal. The associated genes with (+)-Catechin 3-Gallate are Homologous Gene and TSC1 gene.
Cross Reference
Introduction
To understand associated biological information of (+)-Catechin 3-Gallate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with (+)-Catechin 3-Gallate?
(+)-Catechin 3-Gallate is suspected in Epilepsy, Megalencephaly and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with (+)-Catechin 3-Gallate
PubChem Associated disorders and diseases
What pathways are associated with (+)-Catechin 3-Gallate
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with (+)-Catechin 3-Gallate?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with (+)-Catechin 3-Gallate?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with (+)-Catechin 3-Gallate?
There are no associated biomedical information in the current reference collection.
What genes are associated with (+)-Catechin 3-Gallate?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with (+)-Catechin 3-Gallate?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with (+)-Catechin 3-Gallate
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Abib RT et al. | Genoprotective effects of the green tea-derived polyphenol/epicatechin gallate in C6 astroglial cells. | 2010 | J Med Food | pmid:20828315 |
| Mukai D et al. | Potential anthelmintics: polyphenols from the tea plant Camellia sinensis L. are lethally toxic to Caenorhabditis elegans. | 2008 | J Nat Med | pmid:18404315 |
| Naldi M et al. | UHPLC determination of catechins for the quality control of green tea. | 2014 | J Pharm Biomed Anal | pmid:24103292 |
| Müller P and Downard KM | Catechin inhibition of influenza neuraminidase and its molecular basis with mass spectrometry. | 2015 | J Pharm Biomed Anal | pmid:25910046 |
| Jumtee K et al. | Fast GC-FID based metabolic fingerprinting of Japanese green tea leaf for its quality ranking prediction. | 2009 | J Sep Sci | pmid:19569110 |
| Fan DM et al. | Tea polyphenols dominate the short-term tea (Camellia sinensis) leaf litter decomposition. | 2017 Feb. | J Zhejiang Univ Sci B | pmid:28124839 |
| Saito ST et al. | Characterization of the constituents and antioxidant activity of Brazilian green tea (Camellia sinensis var. assamica IAC-259 cultivar) extracts. | 2007 | J. Agric. Food Chem. | pmid:17937477 |
| de Freitas V and Mateus N | Structural features of procyanidin interactions with salivary proteins. | 2001 | J. Agric. Food Chem. | pmid:11262053 |
| Yao L et al. | Seasonal variations of phenolic compounds in Australia-grown tea (Camellia sinensis). | 2005 | J. Agric. Food Chem. | pmid:16076137 |
| Yin J et al. | Reduction of ferrylmyoglobin by theanine and green tea catechins. Importance of specific Acid catalysis. | 2013 | J. Agric. Food Chem. | pmid:23461366 |
| Sánchez-Tena S et al. | Epicatechin gallate impairs colon cancer cell metabolic productivity. | 2013 | J. Agric. Food Chem. | pmid:23594085 |
| Nakagawa T et al. | Protective activity of green tea against free radical- and glucose-mediated protein damage. | 2002 | J. Agric. Food Chem. | pmid:11929306 |
| Hossain SJ et al. | Effects of tea components on the response of GABA(A) receptors expressed in Xenopus Oocytes. | 2002 | J. Agric. Food Chem. | pmid:12083865 |
| Wollmann N and Hofmann T | Compositional and sensory characterization of red wine polymers. | 2013 | J. Agric. Food Chem. | pmid:23387831 |
| Anderson RA and Polansky MM | Tea enhances insulin activity. | 2002 | J. Agric. Food Chem. | pmid:12428980 |
| Sakanaka S | A novel convenient process to obtain a raw decaffeinated tea polyphenol fraction using a lignocellulose column. | 2003 | J. Agric. Food Chem. | pmid:12720405 |
| John KM et al. | Electrofocusing of methanolic extracts for identification of individual flavonol biomolecules in Camellia species. | 2006 | J. Agric. Food Chem. | pmid:16608196 |
| Kohri T et al. | Identification of metabolites of (-)-epicatechin gallate and their metabolic fate in the rat. | 2003 | J. Agric. Food Chem. | pmid:12926915 |
| Hossain SJ et al. | Polyphenol-induced inhibition of the response of na(+)/glucose cotransporter expressed in Xenopus oocytes. | 2002 | J. Agric. Food Chem. | pmid:12188632 |
| Maeda-Yamamoto M et al. | Effects of tea polyphenols on the invasion and matrix metalloproteinases activities of human fibrosarcoma HT1080 cells. | 1999 | J. Agric. Food Chem. | pmid:10794635 |
| Konishi Y et al. | Tea polyphenols inhibit the transport of dietary phenolic acids mediated by the monocarboxylic acid transporter (MCT) in intestinal Caco-2 cell monolayers. | 2003 | J. Agric. Food Chem. | pmid:14640574 |
| Ikeda I et al. | Heat-epimerized tea catechins rich in gallocatechin gallate and catechin gallate are more effective to inhibit cholesterol absorption than tea catechins rich in epigallocatechin gallate and epicatechin gallate. | 2003 | J. Agric. Food Chem. | pmid:14640575 |
| Fulcrand H et al. | Study of wine tannin oligomers by on-line liquid chromatography electrospray ionization mass spectrometry. | 1999 | J. Agric. Food Chem. | pmid:10552410 |
| Chen Z et al. | Degradation of green tea catechins in tea drinks. | 2001 | J. Agric. Food Chem. | pmid:11170614 |
| Ferreira PG et al. | Stimulation of acidic reduction of nitrite to nitric oxide by soybean phenolics: possible relevance to gastrointestinal host defense. | 2011 | J. Agric. Food Chem. | pmid:21510708 |
| Appeldoorn MM et al. | Some phenolic compounds increase the nitric oxide level in endothelial cells in vitro. | 2009 | J. Agric. Food Chem. | pmid:19722703 |
| Saito M et al. | Green tea polyphenols inhibit metalloproteinase activities in the skin, muscle, and blood of rainbow trout. | 2002 | J. Agric. Food Chem. | pmid:12428978 |
| Yilmazer-Musa M et al. | Grape seed and tea extracts and catechin 3-gallates are potent inhibitors of α-amylase and α-glucosidase activity. | 2012 | J. Agric. Food Chem. | pmid:22697360 |
| Kobayashi Y et al. | Green tea polyphenols inhibit the sodium-dependent glucose transporter of intestinal epithelial cells by a competitive mechanism. | 2000 | J. Agric. Food Chem. | pmid:11087528 |
| Mata-Bilbao Mde L et al. | A new LC/MS/MS rapid and sensitive method for the determination of green tea catechins and their metabolites in biological samples. | 2007 | J. Agric. Food Chem. | pmid:17902624 |
| Uekusa Y et al. | Dynamic behavior of tea catechins interacting with lipid membranes as determined by NMR spectroscopy. | 2007 | J. Agric. Food Chem. | pmid:17966973 |
| Danila AM et al. | Determination of rutin, catechin, epicatechin, and epicatechin gallate in buckwheat Fagopyrum esculentum Moench by micro-high-performance liquid chromatography with electrochemical detection. | 2007 | J. Agric. Food Chem. | pmid:17253718 |
| Noda Y and Peterson DG | Structure-reactivity relationships of flavan-3-ols on product generation in aqueous glucose/glycine model systems. | 2007 | J. Agric. Food Chem. | pmid:17394338 |
| Kyle JA et al. | Effects of infusion time and addition of milk on content and absorption of polyphenols from black tea. | 2007 | J. Agric. Food Chem. | pmid:17489604 |
| Wang R et al. | Kinetic study of the thermal stability of tea catechins in aqueous systems using a microwave reactor. | 2006 | J. Agric. Food Chem. | pmid:16881696 |
| Yao R et al. | Dietary flavonoids activate the constitutive androstane receptor (CAR). | 2010 | J. Agric. Food Chem. | pmid:20099825 |
| Shen D et al. | Determination of the predominant catechins in Acacia catechu by liquid chromatography/electrospray ionization-mass spectrometry. | 2006 | J. Agric. Food Chem. | pmid:16637676 |
| Neilson AP et al. | Catechin degradation with concurrent formation of homo- and heterocatechin dimers during in vitro digestion. | 2007 | J. Agric. Food Chem. | pmid:17924707 |
| Nitta Y et al. | Food components inhibiting recombinant human histidine decarboxylase activity. | 2007 | J. Agric. Food Chem. | pmid:17227057 |
| Mitani S et al. | Stopped-flow kinetic study of the aroxyl radical-scavenging action of catechins and vitamin C in ethanol and micellar solutions. | 2008 | J. Agric. Food Chem. | pmid:18500808 |
| Bernal P et al. | Disruption of D-alanyl esterification of Staphylococcus aureus cell wall teichoic acid by the {beta}-lactam resistance modifier (-)-epicatechin gallate. | 2009 | J. Antimicrob. Chemother. | pmid:19307172 |
| Byun MR et al. | (-)-Epicatechin gallate (ECG) stimulates osteoblast differentiation via Runt-related transcription factor 2 (RUNX2) and transcriptional coactivator with PDZ-binding motif (TAZ)-mediated transcriptional activation. | 2014 | J. Biol. Chem. | pmid:24515112 |
| Bernal P et al. | Insertion of epicatechin gallate into the cytoplasmic membrane of methicillin-resistant Staphylococcus aureus disrupts penicillin-binding protein (PBP) 2a-mediated beta-lactam resistance by delocalizing PBP2. | 2010 | J. Biol. Chem. | pmid:20516078 |
| Li C et al. | Green tea polyphenols control dysregulated glutamate dehydrogenase in transgenic mice by hijacking the ADP activation site. | 2011 | J. Biol. Chem. | pmid:21813650 |
| Taniguchi S et al. | Inhibition of heparin-induced tau filament formation by phenothiazines, polyphenols, and porphyrins. | 2005 | J. Biol. Chem. | pmid:15611092 |
| Yoshiki Y et al. | Mechanism of catechin chemiluminescence in the presence of active oxygen. | 1996 May-Jun | J. Biolumin. Chemilumin. | pmid:8844343 |
| Lo HM et al. | Tea polyphenols inhibit rat vascular smooth muscle cell adhesion and migration on collagen and laminin via interference with cell-ECM interaction. | 2007 | J. Biomed. Sci. | pmid:17436062 |
| Landis-Piwowar KR et al. | Methylation suppresses the proteasome-inhibitory function of green tea polyphenols. | 2007 | J. Cell. Physiol. | pmid:17477351 |
| Zhang QH et al. | Simultaneous determination of catechin, epicatechin and epicatechin gallate in rat plasma by LC-ESI-MS/MS for pharmacokinetic studies after oral administration of Cynomorium songaricum extract. | 2012 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:22153330 |
| Peng J et al. | Separation and purification of four phenolic compounds from persimmon by high-speed counter-current chromatography. | 2018 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:29136554 |
| Narumi K et al. | Simultaneous detection of green tea catechins and gallic acid in human serum after ingestion of green tea tablets using ion-pair high-performance liquid chromatography with electrochemical detection. | 2014 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:24342507 |
| Chu KO et al. | Determination of catechins and catechin gallates in tissues by liquid chromatography with coulometric array detection and selective solid phase extraction. | 2004 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:15380714 |
| Fu T et al. | Simultaneous determination of the major active components of tea polyphenols in rat plasma by a simple and specific HPLC assay. | 2008 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:18922746 |
| Liu TT and Yang TS | Effects of water-soluble natural antioxidants on photosensitized oxidation of conjugated linoleic acid in an oil-in-water emulsion system. | 2008 | J. Food Sci. | pmid:18460119 |
| Yuda N et al. | Polyphenols extracted from black tea (Camellia sinensis) residue by hot-compressed water and their inhibitory effect on pancreatic lipase in vitro. | 2012 | J. Food Sci. | pmid:23106349 |
| Chiu CT et al. | Hibiscus sabdariffa leaf polyphenolic extract induces human melanoma cell death, apoptosis, and autophagy. | 2015 | J. Food Sci. | pmid:25694272 |
| Tagashira T et al. | Influence of gallate and pyrogallol moieties on the intestinal absorption of (-)-epicatechin and (-)-epicatechin gallate. | 2012 | J. Food Sci. | pmid:22938538 |
| Chung JH et al. | Green tea formulations with vitamin C and xylitol on enhanced intestinal transport of green tea catechins. | 2013 | J. Food Sci. | pmid:23551173 |
| El-Hawary SA et al. | A profile of bioactive compounds of Rumex vesicarius L. | 2011 | J. Food Sci. | pmid:22417584 |
| Cui L et al. | Extraction of Epigallocatechin Gallate and Epicatechin Gallate from Tea Leaves Using β-Cyclodextrin. | 2017 | J. Food Sci. | pmid:28071811 |
| Ryan P and Hynes MJ | The kinetics and mechanisms of the complex formation and antioxidant behaviour of the polyphenols EGCg and ECG with iron(III). | 2007 | J. Inorg. Biochem. | pmid:17257683 |
| Ghosh KS et al. | Studies on the interaction of copper complexes of (-)-epicatechin gallate and (-)-epigallocatechin gallate with calf thymus DNA. | 2008 | J. Inorg. Biochem. | pmid:18541305 |
| Lin CL et al. | Theaflavins attenuate hepatic lipid accumulation through activating AMPK in human HepG2 cells. | 2007 | J. Lipid Res. | pmid:17720960 |
| Gradisar H et al. | Green tea catechins inhibit bacterial DNA gyrase by interaction with its ATP binding site. | 2007 | J. Med. Chem. | pmid:17228868 |
| Tasdemir D et al. | Inhibition of Plasmodium falciparum fatty acid biosynthesis: evaluation of FabG, FabZ, and FabI as drug targets for flavonoids. | 2006 | J. Med. Chem. | pmid:16722653 |
| Sharma SK et al. | Green tea catechins potentiate triclosan binding to enoyl-ACP reductase from Plasmodium falciparum (PfENR). | 2007 | J. Med. Chem. | pmid:17263522 |
| Hemdan DI et al. | Polyphenols prevent clinorotation-induced expression of atrogenes in mouse C2C12 skeletal myotubes. | 2009 | J. Med. Invest. | pmid:19262011 |
| Ujihara T and Hayashi N | Association of Catechin Molecules in Water: Quantitative Binding Study and Complex Structure Analysis. | 2016 | J. Nat. Prod. | pmid:26720794 |
| Schmidt CA et al. | Catechin derivatives from Parapiptadenia rigida with in vitro wound-healing properties. | 2010 | J. Nat. Prod. | pmid:21080642 |
| Zhou YD et al. | Hypoxia-inducible factor-1 activation by (-)-epicatechin gallate: potential adverse effects of cancer chemoprevention with high-dose green tea extracts. | 2004 | J. Nat. Prod. | pmid:15620252 |
| Ikeda I et al. | Tea catechins with a galloyl moiety suppress postprandial hypertriacylglycerolemia by delaying lymphatic transport of dietary fat in rats. | 2005 | J. Nutr. | pmid:15671206 |
| Henning SM et al. | Tea polyphenols and theaflavins are present in prostate tissue of humans and mice after green and black tea consumption. | 2006 | J. Nutr. | pmid:16772446 |
| Manna S et al. | Tea polyphenols can restrict benzo[a]pyrene-induced lung carcinogenesis by altered expression of p53-associated genes and H-ras, c-myc and cyclin D1. | 2009 | J. Nutr. Biochem. | pmid:18656336 |
| Nomura S et al. | Tea catechins enhance the mRNA expression of uncoupling protein 1 in rat brown adipose tissue. | 2008 | J. Nutr. Biochem. | pmid:18479902 |
| Zhu W et al. | A-type ECG and EGCG dimers inhibit 3T3-L1 differentiation by binding to cholesterol in lipid rafts. | 2017 | J. Nutr. Biochem. | pmid:28772148 |
| Sukhthankar M et al. | A potential proliferative gene, NUDT6, is down-regulated by green tea catechins at the posttranscriptional level. | 2010 | J. Nutr. Biochem. | pmid:19157820 |
| Hosokawa Y et al. | Catechins inhibit CXCL10 production from oncostatin M-stimulated human gingival fibroblasts. | 2010 | J. Nutr. Biochem. | pmid:19616927 |
| Zhu W et al. | A-type ECG and EGCG dimers disturb the structure of 3T3-L1 cell membrane and strongly inhibit its differentiation by targeting peroxisome proliferator-activated receptor γ with miR-27 involved mechanism. | 2015 | J. Nutr. Biochem. | pmid:26145192 |
| Koo SI and Noh SK | Green tea as inhibitor of the intestinal absorption of lipids: potential mechanism for its lipid-lowering effect. | 2007 | J. Nutr. Biochem. | pmid:17296491 |
| Kobayashi K et al. | Strong Inhibition of Secretory Sphingomyelinase by Catechins, Particularly by (-)-Epicatechin 3-O-Gallate and (-)-3'-O-Methylepigallocatechin 3-O-Gallate. | 2016 | J. Nutr. Sci. Vitaminol. | pmid:27264097 |
| Minoda K et al. | Influence of the galloyl moiety in tea catechins on binding affinity for human serum albumin. | 2010 | J. Nutr. Sci. Vitaminol. | pmid:21228505 |
| Hayes CJ et al. | Synthesis and preliminary anticancer activity studies of C4 and C8-modified derivatives of catechin gallate (CG) and epicatechin gallate (ECG). | 2006 | J. Org. Chem. | pmid:17168588 |
| Nakamura H et al. | Green tea catechin inhibits lipopolysaccharide-induced bone resorption in vivo. | 2010 | J. Periodont. Res. | pmid:19602116 |
| Kadowaki M et al. | Presence or absence of a gallate moiety on catechins affects their cellular transport. | 2008 | J. Pharm. Pharmacol. | pmid:18718123 |
| Yokozawa T et al. | (-)-Epicatechin 3-O-gallate ameliorates the damages related to peroxynitrite production by mechanisms distinct from those of other free radical inhibitors. | 2004 | J. Pharm. Pharmacol. | pmid:15005882 |
| Vaidyanathan JB and Walle T | Cellular uptake and efflux of the tea flavonoid (-)epicatechin-3-gallate in the human intestinal cell line Caco-2. | 2003 | J. Pharmacol. Exp. Ther. | pmid:12970388 |
| Bourassa P et al. | The effect of milk alpha-casein on the antioxidant activity of tea polyphenols. | 2013 | J. Photochem. Photobiol. B, Biol. | pmid:24001682 |
| Park JH et al. | Ambivalent role of gallated catechins in glucose tolerance in humans: a novel insight into non-absorbable gallated catechin-derived inhibitors of glucose absorption. | 2009 | J. Physiol. Pharmacol. | pmid:20065503 |
| Sasaki T et al. | Green tea catechins increase the force of contraction in isolated guinea pig atrial muscle preparations by increasing the amplitude of intracellular Ca2+ concentration. | 2012 | J. Vet. Med. Sci. | pmid:22864409 |
| Matsumoto N et al. | Inhibitory effects of tea catechins, black tea extract and oolong tea extract on hepatocarcinogenesis in rat. | 1996 | Jpn. J. Cancer Res. | pmid:8957060 |
| Malik S et al. | Molecular mechanisms underlying attenuation of cisplatin-induced acute kidney injury by epicatechin gallate. | 2016 | Lab. Invest. | pmid:27239733 |
| Shah S et al. | The polyphenol (-)-epicatechin gallate disrupts the secretion of virulence-related proteins by Staphylococcus aureus. | 2008 | Lett. Appl. Microbiol. | pmid:18069979 |
| Annabi B et al. | Inhibition of HuR and MMP-9 expression in macrophage-differentiated HL-60 myeloid leukemia cells by green tea polyphenol EGCg. | 2007 | Leuk. Res. | pmid:17081606 |
| Coyle CH et al. | Antioxidant effects of green tea and its polyphenols on bladder cells. | 2008 | Life Sci. | pmid:18544457 |
| Zhang A et al. | Inhibitory effects of jasmine green tea epicatechin isomers on free radical-induced lysis of red blood cells. | 1997 | Life Sci. | pmid:9244364 |
| Hirao K et al. | Tea catechins reduce inflammatory reactions via mitogen-activated protein kinase pathways in toll-like receptor 2 ligand-stimulated dental pulp cells. | 2010 | Life Sci. | pmid:20176036 |
| Van Dyke K et al. | Green tea extract and its polyphenols markedly inhibit luminol-dependent chemiluminescence activated by peroxynitrite or SIN-1. | 2000 Jan-Feb | Luminescence | pmid:10660664 |
| Ishizu T et al. | Diastereomeric difference of inclusion modes between (-)-epicatechin gallate, (-)-epigallocatechin gallate and (+)-gallocatechin gallate, with beta-cyclodextrin in aqueous solvent. | 2008 | Magn Reson Chem | pmid:18318450 |
| Thephinlap C et al. | Epigallocatechin-3-gallate and epicatechin-3-gallate from green tea decrease plasma non-transferrin bound iron and erythrocyte oxidative stress. | 2007 | Med Chem | pmid:17504202 |
| Cunha CA et al. | Green tea extract supplementation induces the lipolytic pathway, attenuates obesity, and reduces low-grade inflammation in mice fed a high-fat diet. | 2013 | Mediators Inflamm. | pmid:23431242 |