Epicatechin-3-gallate

Epicatechin-3-gallate is a lipid of Polyketides (PK) class. Epicatechin-3-gallate is associated with abnormalities such as Epilepsy and Megalencephaly. The involved functions are known as Docking, Drug Interactions, inhibitors, Oxidation and Inflammation Process. Epicatechin-3-gallate often locates in Solitary microtubule component of centriole or axonemal complex, Palmar surface, Glial and peritoneal. The associated genes with Epicatechin-3-gallate are Homologous Gene and TSC1 gene.

Cross Reference

Introduction

To understand associated biological information of Epicatechin-3-gallate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Epicatechin-3-gallate?

Epicatechin-3-gallate is suspected in Epilepsy, Megalencephaly and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Epicatechin-3-gallate

MeSH term MeSH ID Detail
Cicatrix D002921 9 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Total 2

PubChem Associated disorders and diseases

What pathways are associated with Epicatechin-3-gallate

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Epicatechin-3-gallate?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Epicatechin-3-gallate?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Epicatechin-3-gallate?

There are no associated biomedical information in the current reference collection.

What genes are associated with Epicatechin-3-gallate?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Epicatechin-3-gallate?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Epicatechin-3-gallate

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Authors Title Published Journal PubMed Link
Yao L et al. Seasonal variations of phenolic compounds in Australia-grown tea (Camellia sinensis). 2005 J. Agric. Food Chem. pmid:16076137
Mukai K et al. Kinetic study of the quenching reaction of singlet oxygen by tea catechins in ethanol solution. 2005 Free Radic. Biol. Med. pmid:16109305
Ikeda I et al. Tea catechins with a galloyl moiety suppress postprandial hypertriacylglycerolemia by delaying lymphatic transport of dietary fat in rats. 2005 J. Nutr. pmid:15671206
Nakamuta M et al. Epigallocatechin-3-gallate, a polyphenol component of green tea, suppresses both collagen production and collagenase activity in hepatic stellate cells. 2005 Int. J. Mol. Med. pmid:16142404
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Anderson JC et al. Synthesis and antibacterial activity of hydrolytically stable (-)-epicatechin gallate analogues for the modulation of beta-lactam resistance in Staphylococcus aureus. 2005 Bioorg. Med. Chem. Lett. pmid:15863332
El Bedoui J et al. Catechins prevent vascular smooth muscle cell invasion by inhibiting MT1-MMP activity and MMP-2 expression. 2005 Cardiovasc. Res. pmid:15885676
Yamazaki T et al. Biosynthesized tea polyphenols inactivate Chlamydia trachomatis in vitro. 2005 Antimicrob. Agents Chemother. pmid:15917555
Song JM et al. Antiviral effect of catechins in green tea on influenza virus. 2005 Antiviral Res. pmid:16137775
Luximon-Ramma A et al. Assessment of the polyphenolic composition of the organic extracts of Mauritian black teas: a potential contributor to their antioxidant functions. 2006 Biofactors pmid:17012766
Jo JY et al. Catalytic inhibition of human DNA topoisomerase II by interactions of grape cell culture polyphenols. 2006 J. Agric. Food Chem. pmid:16536579
Daniel KG et al. Methylation of green tea polyphenols affects their binding to and inhibitory poses of the proteasome beta5 subunit. 2006 Int. J. Mol. Med. pmid:16964415
Ghosh KS et al. Copper complexes of (-)-epicatechin gallate and (-)-epigallocatechin gallate act as inhibitors of Ribonuclease A. 2006 FEBS Lett. pmid:16884715
Lim YC et al. Growth inhibition and apoptosis by (-)-epicatechin gallate are mediated by cyclin D1 suppression in head and neck squamous carcinoma cells. 2006 Eur. J. Cancer pmid:17045795
Hayes CJ et al. Synthesis and preliminary anticancer activity studies of C4 and C8-modified derivatives of catechin gallate (CG) and epicatechin gallate (ECG). 2006 J. Org. Chem. pmid:17168588
Henning SM et al. Tea polyphenols and theaflavins are present in prostate tissue of humans and mice after green and black tea consumption. 2006 J. Nutr. pmid:16772446