MeSH term | MeSH ID | Detail |
---|---|---|
Colonic Neoplasms | D003110 | 161 associated lipids |
Cicatrix | D002921 | 9 associated lipids |
Epicatechin-3-gallate is a lipid of Polyketides (PK) class. Epicatechin-3-gallate is associated with abnormalities such as Epilepsy and Megalencephaly. The involved functions are known as Docking, Drug Interactions, inhibitors, Oxidation and Inflammation Process. Epicatechin-3-gallate often locates in Solitary microtubule component of centriole or axonemal complex, Palmar surface, Glial and peritoneal. The associated genes with Epicatechin-3-gallate are Homologous Gene and TSC1 gene.
To understand associated biological information of Epicatechin-3-gallate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Epicatechin-3-gallate is suspected in Epilepsy, Megalencephaly and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Epicatechin-3-gallate
MeSH term | MeSH ID | Detail |
---|---|---|
Colonic Neoplasms | D003110 | 161 associated lipids |
Cicatrix | D002921 | 9 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Feucht W et al. | Flavanols in somatic cell division and male meiosis of tea (Camellia sinensis) anthers. | 2005 | Plant Biol (Stuttg) | pmid:15822012 |
Chen D et al. | Inhibition of human liver catechol-O-methyltransferase by tea catechins and their metabolites: structure-activity relationship and molecular-modeling studies. | 2005 | Biochem. Pharmacol. | pmid:15857617 |
Anderson JC et al. | Synthesis and antibacterial activity of hydrolytically stable (-)-epicatechin gallate analogues for the modulation of beta-lactam resistance in Staphylococcus aureus. | 2005 | Bioorg. Med. Chem. Lett. | pmid:15863332 |
El Bedoui J et al. | Catechins prevent vascular smooth muscle cell invasion by inhibiting MT1-MMP activity and MMP-2 expression. | 2005 | Cardiovasc. Res. | pmid:15885676 |
Anger DL et al. | Heteroactivation of cytochrome P450 1A1 by teas and tea polyphenols. | 2005 | Br. J. Pharmacol. | pmid:15895106 |
Navarro-Perán E et al. | Kinetics of the inhibition of bovine liver dihydrofolate reductase by tea catechins: origin of slow-binding inhibition and pH studies. | 2005 | Biochemistry | pmid:15895994 |
Ikeda I et al. | Dietary gallate esters of tea catechins reduce deposition of visceral fat, hepatic triacylglycerol, and activities of hepatic enzymes related to fatty acid synthesis in rats. | 2005 | Biosci. Biotechnol. Biochem. | pmid:15914933 |
Yamazaki T et al. | Biosynthesized tea polyphenols inactivate Chlamydia trachomatis in vitro. | 2005 | Antimicrob. Agents Chemother. | pmid:15917555 |
Zhang R et al. | Novel inhibitors of fatty-acid synthase from green tea (Camellia sinensis Xihu Longjing) with high activity and a new reacting site. | 2006 | Biotechnol. Appl. Biochem. | pmid:15943584 |
Yao L et al. | Seasonal variations of phenolic compounds in Australia-grown tea (Camellia sinensis). | 2005 | J. Agric. Food Chem. | pmid:16076137 |
Kumar NS and Rajapaksha M | Separation of catechin constituents from five tea cultivars using high-speed counter-current chromatography. | 2005 | J Chromatogr A | pmid:16078712 |
Mukai K et al. | Kinetic study of the quenching reaction of singlet oxygen by tea catechins in ethanol solution. | 2005 | Free Radic. Biol. Med. | pmid:16109305 |
Tsang C et al. | The absorption, metabolism and excretion of flavan-3-ols and procyanidins following the ingestion of a grape seed extract by rats. | 2005 | Br. J. Nutr. | pmid:16115350 |
Song JM et al. | Antiviral effect of catechins in green tea on influenza virus. | 2005 | Antiviral Res. | pmid:16137775 |
Nakamuta M et al. | Epigallocatechin-3-gallate, a polyphenol component of green tea, suppresses both collagen production and collagenase activity in hepatic stellate cells. | 2005 | Int. J. Mol. Med. | pmid:16142404 |
Agusta A et al. | Stereoselective oxidation at C-4 of flavans by the endophytic fungus Diaporthe sp. isolated from a tea plant. | 2005 | Chem. Pharm. Bull. | pmid:16327190 |
Ikeda I et al. | Tea catechins decrease micellar solubility and intestinal absorption of cholesterol in rats. | 1992 | Biochim. Biophys. Acta | pmid:1643098 |
Stapleton PD et al. | Potentiation of catechin gallate-mediated sensitization of Staphylococcus aureus to oxacillin by nongalloylated catechins. | 2006 | Antimicrob. Agents Chemother. | pmid:16436737 |
Bigelow RL and Cardelli JA | The green tea catechins, (-)-Epigallocatechin-3-gallate (EGCG) and (-)-Epicatechin-3-gallate (ECG), inhibit HGF/Met signaling in immortalized and tumorigenic breast epithelial cells. | 2006 | Oncogene | pmid:16449979 |
Galati G et al. | Cellular and in vivo hepatotoxicity caused by green tea phenolic acids and catechins. | 2006 | Free Radic. Biol. Med. | pmid:16458187 |