Epicatechin-3-gallate

Epicatechin-3-gallate is a lipid of Polyketides (PK) class. Epicatechin-3-gallate is associated with abnormalities such as Epilepsy and Megalencephaly. The involved functions are known as Docking, Drug Interactions, inhibitors, Oxidation and Inflammation Process. Epicatechin-3-gallate often locates in Solitary microtubule component of centriole or axonemal complex, Palmar surface, Glial and peritoneal. The associated genes with Epicatechin-3-gallate are Homologous Gene and TSC1 gene.

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Introduction

To understand associated biological information of Epicatechin-3-gallate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Epicatechin-3-gallate?

Epicatechin-3-gallate is suspected in Epilepsy, Megalencephaly and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Epicatechin-3-gallate

MeSH term MeSH ID Detail
Cicatrix D002921 9 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Total 2

PubChem Associated disorders and diseases

What pathways are associated with Epicatechin-3-gallate

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Epicatechin-3-gallate?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Epicatechin-3-gallate?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Epicatechin-3-gallate?

There are no associated biomedical information in the current reference collection.

What genes are associated with Epicatechin-3-gallate?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Epicatechin-3-gallate?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Epicatechin-3-gallate

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Authors Title Published Journal PubMed Link
Yokozawa T et al. (-)-Epicatechin 3-O-gallate ameliorates the damages related to peroxynitrite production by mechanisms distinct from those of other free radical inhibitors. 2004 J. Pharm. Pharmacol. pmid:15005882
Okamoto M et al. Inhibitory effect of green tea catechins on cysteine proteinases in Porphyromonas gingivalis. 2004 Oral Microbiol. Immunol. pmid:14871352
Caturla N et al. The relationship between the antioxidant and the antibacterial properties of galloylated catechins and the structure of phospholipid model membranes. 2003 Free Radic. Biol. Med. pmid:12633742
Vaidyanathan JB and Walle T Cellular uptake and efflux of the tea flavonoid (-)epicatechin-3-gallate in the human intestinal cell line Caco-2. 2003 J. Pharmacol. Exp. Ther. pmid:12970388
Chen L et al. Tea catechins protect against lead-induced ROS formation, mitochondrial dysfunction, and calcium dysregulation in PC12 cells. 2003 Chem. Res. Toxicol. pmid:12971804
Sakanaka S A novel convenient process to obtain a raw decaffeinated tea polyphenol fraction using a lignocellulose column. 2003 J. Agric. Food Chem. pmid:12720405
Takizawa Y et al. Pharmacokinetics of (-)-epicatechin-3-O-gallate, an active component of Onpi-to, in rats. 2003 Biol. Pharm. Bull. pmid:12736498
Morré DJ et al. Tea catechin synergies in inhibition of cancer cell proliferation and of a cancer specific cell surface oxidase (ECTO-NOX). 2003 Pharmacol. Toxicol. pmid:12753411
Kohri T et al. Identification of metabolites of (-)-epicatechin gallate and their metabolic fate in the rat. 2003 J. Agric. Food Chem. pmid:12926915
Wang X et al. The galloyl moiety of green tea catechins is the critical structural feature to inhibit fatty-acid synthase. 2003 Biochem. Pharmacol. pmid:14599562