MeSH term | MeSH ID | Detail |
---|---|---|
Cicatrix | D002921 | 9 associated lipids |
Colonic Neoplasms | D003110 | 161 associated lipids |
Epicatechin-3-gallate is a lipid of Polyketides (PK) class. Epicatechin-3-gallate is associated with abnormalities such as Epilepsy and Megalencephaly. The involved functions are known as Docking, Drug Interactions, inhibitors, Oxidation and Inflammation Process. Epicatechin-3-gallate often locates in Solitary microtubule component of centriole or axonemal complex, Palmar surface, Glial and peritoneal. The associated genes with Epicatechin-3-gallate are Homologous Gene and TSC1 gene.
To understand associated biological information of Epicatechin-3-gallate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Epicatechin-3-gallate is suspected in Epilepsy, Megalencephaly and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Epicatechin-3-gallate
MeSH term | MeSH ID | Detail |
---|---|---|
Cicatrix | D002921 | 9 associated lipids |
Colonic Neoplasms | D003110 | 161 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Yokozawa T et al. | (-)-Epicatechin 3-O-gallate ameliorates the damages related to peroxynitrite production by mechanisms distinct from those of other free radical inhibitors. | 2004 | J. Pharm. Pharmacol. | pmid:15005882 |
Okamoto M et al. | Inhibitory effect of green tea catechins on cysteine proteinases in Porphyromonas gingivalis. | 2004 | Oral Microbiol. Immunol. | pmid:14871352 |
Caturla N et al. | The relationship between the antioxidant and the antibacterial properties of galloylated catechins and the structure of phospholipid model membranes. | 2003 | Free Radic. Biol. Med. | pmid:12633742 |
Vaidyanathan JB and Walle T | Cellular uptake and efflux of the tea flavonoid (-)epicatechin-3-gallate in the human intestinal cell line Caco-2. | 2003 | J. Pharmacol. Exp. Ther. | pmid:12970388 |
Chen L et al. | Tea catechins protect against lead-induced ROS formation, mitochondrial dysfunction, and calcium dysregulation in PC12 cells. | 2003 | Chem. Res. Toxicol. | pmid:12971804 |
Sakanaka S | A novel convenient process to obtain a raw decaffeinated tea polyphenol fraction using a lignocellulose column. | 2003 | J. Agric. Food Chem. | pmid:12720405 |
Takizawa Y et al. | Pharmacokinetics of (-)-epicatechin-3-O-gallate, an active component of Onpi-to, in rats. | 2003 | Biol. Pharm. Bull. | pmid:12736498 |
Morré DJ et al. | Tea catechin synergies in inhibition of cancer cell proliferation and of a cancer specific cell surface oxidase (ECTO-NOX). | 2003 | Pharmacol. Toxicol. | pmid:12753411 |
Kohri T et al. | Identification of metabolites of (-)-epicatechin gallate and their metabolic fate in the rat. | 2003 | J. Agric. Food Chem. | pmid:12926915 |
Wang X et al. | The galloyl moiety of green tea catechins is the critical structural feature to inhibit fatty-acid synthase. | 2003 | Biochem. Pharmacol. | pmid:14599562 |