Epicatechin-3-gallate

Epicatechin-3-gallate is a lipid of Polyketides (PK) class. Epicatechin-3-gallate is associated with abnormalities such as Epilepsy and Megalencephaly. The involved functions are known as Docking, Drug Interactions, inhibitors, Oxidation and Inflammation Process. Epicatechin-3-gallate often locates in Solitary microtubule component of centriole or axonemal complex, Palmar surface, Glial and peritoneal. The associated genes with Epicatechin-3-gallate are Homologous Gene and TSC1 gene.

Cross Reference

Introduction

To understand associated biological information of Epicatechin-3-gallate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Epicatechin-3-gallate?

Epicatechin-3-gallate is suspected in Epilepsy, Megalencephaly and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Epicatechin-3-gallate

MeSH term MeSH ID Detail
Cicatrix D002921 9 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Total 2

PubChem Associated disorders and diseases

What pathways are associated with Epicatechin-3-gallate

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Epicatechin-3-gallate?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Epicatechin-3-gallate?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Epicatechin-3-gallate?

There are no associated biomedical information in the current reference collection.

What genes are associated with Epicatechin-3-gallate?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Epicatechin-3-gallate?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Epicatechin-3-gallate

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Authors Title Published Journal PubMed Link
Farhan M et al. Mobilization of Nuclear Copper by Green Tea Polyphenol Epicatechin-3-Gallate and Subsequent Prooxidant Breakage of Cellular DNA: Implications for Cancer Chemotherapy. 2016 Int J Mol Sci pmid:28035959
Rosado H et al. Impact of the β-Lactam Resistance Modifier (-)-Epicatechin Gallate on the Non-Random Distribution of Phospholipids across the Cytoplasmic Membrane of Staphylococcus aureus. 2015 Int J Mol Sci pmid:26213914
Shen JM et al. Chitosan-based luminescent/magnetic hybrid nanogels for insulin delivery, cell imaging, and antidiabetic research of dietary supplements. 2012 Int J Pharm pmid:22342466
Zhang L et al. Investigation of intestinal absorption and disposition of green tea catechins by Caco-2 monolayer model. 2004 Int J Pharm pmid:15541906
Jun X et al. Separation of major catechins from green tea by ultrahigh pressure extraction. 2010 Int J Pharm pmid:19874878
Stapleton PD et al. Modulation of beta-lactam resistance in Staphylococcus aureus by catechins and gallates. 2004 Int. J. Antimicrob. Agents pmid:15120724
Cushnie TP and Lamb AJ Recent advances in understanding the antibacterial properties of flavonoids. 2011 Int. J. Antimicrob. Agents pmid:21514796
Kim JH et al. Inhibitory activity of (-)-epicatechin-3,5-O-digallate on α-glucosidase and in silico analysis. 2018 Int. J. Biol. Macromol. pmid:28958819
Lei S et al. Effective synthesis of theaflavin-3,3'-digallate with epigallocatechin-3-O-gallate and epicatechin gallate as substrates by using immobilized pear polyphenol oxidase. 2017 Int. J. Biol. Macromol. pmid:27780760
Ghosh S et al. (-)-Epicatechin gallate prevents alkali-salt mediated fibrillogenesis of hen egg white lysozyme. 2013 Int. J. Biol. Macromol. pmid:23219698
Krych J and Gebicka L Catalase is inhibited by flavonoids. 2013 Int. J. Biol. Macromol. pmid:23567286
Stapleton PD et al. Epicatechin gallate, a component of green tea, reduces halotolerance in Staphylococcus aureus. 2006 Int. J. Food Microbiol. pmid:16839636
Nakamuta M et al. Epigallocatechin-3-gallate, a polyphenol component of green tea, suppresses both collagen production and collagenase activity in hepatic stellate cells. 2005 Int. J. Mol. Med. pmid:16142404
Daniel KG et al. Methylation of green tea polyphenols affects their binding to and inhibitory poses of the proteasome beta5 subunit. 2006 Int. J. Mol. Med. pmid:16964415
Park JS et al. EGCG inhibits recepteur d'origine nantais expression by suppressing Egr-1 in gastric cancer cells. 2013 Int. J. Oncol. pmid:23337910
Roman MC Determination of catechins and caffeine in camillia sinensis raw materials, extracts, and dietary supplements by HPLC-uv: single-laboratory validation. 2013 Sep-Oct J AOAC Int pmid:24282928
Koch W et al. Catechin Composition and Antioxidant Activity of Black Teas in Relation to Brewing Time. 2017 J AOAC Int pmid:28707612
Peek J et al. Identification of Novel Polyphenolic Inhibitors of Shikimate Dehydrogenase (AroE). 2014 J Biomol Screen pmid:24632659
Haginaka J et al. Uniformly-sized, molecularly imprinted polymers for (-)-epigallocatechin gallate, -epicatechin gallate and -gallocatechin gallate by multi-step swelling and polymerization method. 2007 J Chromatogr A pmid:17070533
Si W et al. Bioassay-guided purification and identification of antimicrobial components in Chinese green tea extract. 2006 J Chromatogr A pmid:16797571