MeSH term | MeSH ID | Detail |
---|---|---|
Cicatrix | D002921 | 9 associated lipids |
Colonic Neoplasms | D003110 | 161 associated lipids |
Epicatechin-3-gallate is a lipid of Polyketides (PK) class. Epicatechin-3-gallate is associated with abnormalities such as Epilepsy and Megalencephaly. The involved functions are known as Docking, Drug Interactions, inhibitors, Oxidation and Inflammation Process. Epicatechin-3-gallate often locates in Solitary microtubule component of centriole or axonemal complex, Palmar surface, Glial and peritoneal. The associated genes with Epicatechin-3-gallate are Homologous Gene and TSC1 gene.
To understand associated biological information of Epicatechin-3-gallate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Epicatechin-3-gallate is suspected in Epilepsy, Megalencephaly and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Epicatechin-3-gallate
MeSH term | MeSH ID | Detail |
---|---|---|
Cicatrix | D002921 | 9 associated lipids |
Colonic Neoplasms | D003110 | 161 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Farhan M et al. | Mobilization of Nuclear Copper by Green Tea Polyphenol Epicatechin-3-Gallate and Subsequent Prooxidant Breakage of Cellular DNA: Implications for Cancer Chemotherapy. | 2016 | Int J Mol Sci | pmid:28035959 |
Rosado H et al. | Impact of the β-Lactam Resistance Modifier (-)-Epicatechin Gallate on the Non-Random Distribution of Phospholipids across the Cytoplasmic Membrane of Staphylococcus aureus. | 2015 | Int J Mol Sci | pmid:26213914 |
Shen JM et al. | Chitosan-based luminescent/magnetic hybrid nanogels for insulin delivery, cell imaging, and antidiabetic research of dietary supplements. | 2012 | Int J Pharm | pmid:22342466 |
Zhang L et al. | Investigation of intestinal absorption and disposition of green tea catechins by Caco-2 monolayer model. | 2004 | Int J Pharm | pmid:15541906 |
Jun X et al. | Separation of major catechins from green tea by ultrahigh pressure extraction. | 2010 | Int J Pharm | pmid:19874878 |
Stapleton PD et al. | Modulation of beta-lactam resistance in Staphylococcus aureus by catechins and gallates. | 2004 | Int. J. Antimicrob. Agents | pmid:15120724 |
Cushnie TP and Lamb AJ | Recent advances in understanding the antibacterial properties of flavonoids. | 2011 | Int. J. Antimicrob. Agents | pmid:21514796 |
Kim JH et al. | Inhibitory activity of (-)-epicatechin-3,5-O-digallate on α-glucosidase and in silico analysis. | 2018 | Int. J. Biol. Macromol. | pmid:28958819 |
Lei S et al. | Effective synthesis of theaflavin-3,3'-digallate with epigallocatechin-3-O-gallate and epicatechin gallate as substrates by using immobilized pear polyphenol oxidase. | 2017 | Int. J. Biol. Macromol. | pmid:27780760 |
Ghosh S et al. | (-)-Epicatechin gallate prevents alkali-salt mediated fibrillogenesis of hen egg white lysozyme. | 2013 | Int. J. Biol. Macromol. | pmid:23219698 |
Krych J and Gebicka L | Catalase is inhibited by flavonoids. | 2013 | Int. J. Biol. Macromol. | pmid:23567286 |
Stapleton PD et al. | Epicatechin gallate, a component of green tea, reduces halotolerance in Staphylococcus aureus. | 2006 | Int. J. Food Microbiol. | pmid:16839636 |
Nakamuta M et al. | Epigallocatechin-3-gallate, a polyphenol component of green tea, suppresses both collagen production and collagenase activity in hepatic stellate cells. | 2005 | Int. J. Mol. Med. | pmid:16142404 |
Daniel KG et al. | Methylation of green tea polyphenols affects their binding to and inhibitory poses of the proteasome beta5 subunit. | 2006 | Int. J. Mol. Med. | pmid:16964415 |
Park JS et al. | EGCG inhibits recepteur d'origine nantais expression by suppressing Egr-1 in gastric cancer cells. | 2013 | Int. J. Oncol. | pmid:23337910 |
Roman MC | Determination of catechins and caffeine in camillia sinensis raw materials, extracts, and dietary supplements by HPLC-uv: single-laboratory validation. | 2013 Sep-Oct | J AOAC Int | pmid:24282928 |
Koch W et al. | Catechin Composition and Antioxidant Activity of Black Teas in Relation to Brewing Time. | 2017 | J AOAC Int | pmid:28707612 |
Peek J et al. | Identification of Novel Polyphenolic Inhibitors of Shikimate Dehydrogenase (AroE). | 2014 | J Biomol Screen | pmid:24632659 |
Haginaka J et al. | Uniformly-sized, molecularly imprinted polymers for (-)-epigallocatechin gallate, -epicatechin gallate and -gallocatechin gallate by multi-step swelling and polymerization method. | 2007 | J Chromatogr A | pmid:17070533 |
Si W et al. | Bioassay-guided purification and identification of antimicrobial components in Chinese green tea extract. | 2006 | J Chromatogr A | pmid:16797571 |