Epicatechin-3-gallate

Epicatechin-3-gallate is a lipid of Polyketides (PK) class. Epicatechin-3-gallate is associated with abnormalities such as Epilepsy and Megalencephaly. The involved functions are known as Docking, Drug Interactions, inhibitors, Oxidation and Inflammation Process. Epicatechin-3-gallate often locates in Solitary microtubule component of centriole or axonemal complex, Palmar surface, Glial and peritoneal. The associated genes with Epicatechin-3-gallate are Homologous Gene and TSC1 gene.

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Introduction

To understand associated biological information of Epicatechin-3-gallate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Epicatechin-3-gallate?

Epicatechin-3-gallate is suspected in Epilepsy, Megalencephaly and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Epicatechin-3-gallate

MeSH term MeSH ID Detail
Cicatrix D002921 9 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Total 2

PubChem Associated disorders and diseases

What pathways are associated with Epicatechin-3-gallate

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Epicatechin-3-gallate?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Epicatechin-3-gallate?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Epicatechin-3-gallate?

There are no associated biomedical information in the current reference collection.

What genes are associated with Epicatechin-3-gallate?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Epicatechin-3-gallate?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Epicatechin-3-gallate

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Authors Title Published Journal PubMed Link
Thephinlap C et al. Epigallocatechin-3-gallate and epicatechin-3-gallate from green tea decrease plasma non-transferrin bound iron and erythrocyte oxidative stress. 2007 Med Chem pmid:17504202
Liu TT and Yang TS Effects of water-soluble natural antioxidants on photosensitized oxidation of conjugated linoleic acid in an oil-in-water emulsion system. 2008 J. Food Sci. pmid:18460119
Coyle CH et al. Antioxidant effects of green tea and its polyphenols on bladder cells. 2008 Life Sci. pmid:18544457
Kawai Y et al. (-)-Epicatechin gallate accumulates in foamy macrophages in human atherosclerotic aorta: implication in the anti-atherosclerotic actions of tea catechins. 2008 Biochem. Biophys. Res. Commun. pmid:18657514
Kadowaki M et al. Presence or absence of a gallate moiety on catechins affects their cellular transport. 2008 J. Pharm. Pharmacol. pmid:18718123
Kawai Y et al. Galloylated catechins as potent inhibitors of hypochlorous acid-induced DNA damage. 2008 Chem. Res. Toxicol. pmid:18512968
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Li D et al. Identification of a PKCepsilon-dependent regulation of myocardial contraction by epicatechin-3-gallate. 2008 Am. J. Physiol. Heart Circ. Physiol. pmid:17951366
Abib RT et al. Epicatechin gallate increases glutamate uptake and S100B secretion in C6 cell lineage. 2008 Mol. Cell. Biochem. pmid:18066651
Shah S et al. The polyphenol (-)-epicatechin gallate disrupts the secretion of virulence-related proteins by Staphylococcus aureus. 2008 Lett. Appl. Microbiol. pmid:18069979
Mata-Bilbao Mde L et al. Absorption and pharmacokinetics of green tea catechins in beagles. 2008 Br. J. Nutr. pmid:18205995
Ishizu T et al. Diastereomeric difference of inclusion modes between (-)-epicatechin gallate, (-)-epigallocatechin gallate and (+)-gallocatechin gallate, with beta-cyclodextrin in aqueous solvent. 2008 Magn Reson Chem pmid:18318450
Mukai D et al. Potential anthelmintics: polyphenols from the tea plant Camellia sinensis L. are lethally toxic to Caenorhabditis elegans. 2008 J Nat Med pmid:18404315
Fujimura Y et al. The impact of the 67kDa laminin receptor on both cell-surface binding and anti-allergic action of tea catechins. 2008 Arch. Biochem. Biophys. pmid:18358230
Mitani S et al. Stopped-flow kinetic study of the aroxyl radical-scavenging action of catechins and vitamin C in ethanol and micellar solutions. 2008 J. Agric. Food Chem. pmid:18500808
Ghosh KS et al. Studies on the interaction of copper complexes of (-)-epicatechin gallate and (-)-epigallocatechin gallate with calf thymus DNA. 2008 J. Inorg. Biochem. pmid:18541305
Appeldoorn MM et al. Some phenolic compounds increase the nitric oxide level in endothelial cells in vitro. 2009 J. Agric. Food Chem. pmid:19722703
Liu J et al. Borate complexation-assisted field-enhanced sample injection for on-line preconcentration of cis-diol-containing compounds in capillary electrophoresis. 2009 Talanta pmid:19836518