| MeSH term | MeSH ID | Detail |
|---|---|---|
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Cicatrix | D002921 | 9 associated lipids |
Total
2
Epicatechin-3-gallate
Epicatechin-3-gallate is a lipid of Polyketides (PK) class. Epicatechin-3-gallate is associated with abnormalities such as Epilepsy and Megalencephaly. The involved functions are known as Docking, Drug Interactions, inhibitors, Oxidation and Inflammation Process. Epicatechin-3-gallate often locates in Solitary microtubule component of centriole or axonemal complex, Palmar surface, Glial and peritoneal. The associated genes with Epicatechin-3-gallate are Homologous Gene and TSC1 gene.
Cross Reference
Introduction
To understand associated biological information of Epicatechin-3-gallate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Epicatechin-3-gallate?
Epicatechin-3-gallate is suspected in Epilepsy, Megalencephaly and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Epicatechin-3-gallate
PubChem Associated disorders and diseases
What pathways are associated with Epicatechin-3-gallate
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Epicatechin-3-gallate?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Epicatechin-3-gallate?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Epicatechin-3-gallate?
There are no associated biomedical information in the current reference collection.
What genes are associated with Epicatechin-3-gallate?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Epicatechin-3-gallate?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Epicatechin-3-gallate
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Schantz M et al. | Metabolism of green tea catechins by the human small intestine. | 2010 | Biotechnol J | pmid:20931601 |
| Sukhthankar M et al. | A potential proliferative gene, NUDT6, is down-regulated by green tea catechins at the posttranscriptional level. | 2010 | J. Nutr. Biochem. | pmid:19157820 |
| Hosokawa Y et al. | Catechins inhibit CXCL10 production from oncostatin M-stimulated human gingival fibroblasts. | 2010 | J. Nutr. Biochem. | pmid:19616927 |
| Kim HJ et al. | Epicatechin gallate suppresses oxidative stress-induced MUC5AC overexpression by interaction with epidermal growth factor receptor. | 2010 | Am. J. Respir. Cell Mol. Biol. | pmid:19855084 |
| Hosokawa Y et al. | Tea polyphenols inhibit IL-6 production in tumor necrosis factor superfamily 14-stimulated human gingival fibroblasts. | 2010 | Mol Nutr Food Res | pmid:20461739 |
| Jackson JK et al. | The inhibition of collagenase induced degradation of collagen by the galloyl-containing polyphenols tannic acid, epigallocatechin gallate and epicatechin gallate. | 2010 | J Mater Sci Mater Med | pmid:20162329 |
| Hirao K et al. | Tea catechins reduce inflammatory reactions via mitogen-activated protein kinase pathways in toll-like receptor 2 ligand-stimulated dental pulp cells. | 2010 | Life Sci. | pmid:20176036 |
| Ferrer-Gallego R et al. | Statistical correlation between flavanolic composition, colour and sensorial parameters in grape seed during ripening. | 2010 | Anal. Chim. Acta | pmid:20103139 |
| Soe WM et al. | In vitro drug interactions of gallates with antibiotics in Staphylococcus Aureus. | 2010 | Front Biosci (Elite Ed) | pmid:20036910 |
| Ziaedini A et al. | Extraction of antioxidants and caffeine from green tea (Camelia sinensis) leaves: kinetics and modeling. | 2010 | Food Sci Technol Int | pmid:21339166 |
| Minoda K et al. | Influence of the galloyl moiety in tea catechins on binding affinity for human serum albumin. | 2010 | J. Nutr. Sci. Vitaminol. | pmid:21228505 |
| Schmidt CA et al. | Catechin derivatives from Parapiptadenia rigida with in vitro wound-healing properties. | 2010 | J. Nat. Prod. | pmid:21080642 |
| Nakamura H et al. | Green tea catechin inhibits lipopolysaccharide-induced bone resorption in vivo. | 2010 | J. Periodont. Res. | pmid:19602116 |
| Cao P et al. | Effect of green tea catechins and hydrolyzable tannins on benzo[a]pyrene-induced DNA adducts and structure-activity relationship. | 2010 | Chem. Res. Toxicol. | pmid:20218540 |
| Korte G et al. | Tea catechins' affinity for human cannabinoid receptors. | 2010 | Phytomedicine | pmid:19897346 |
| Ishii T et al. | Binding affinity of tea catechins for HSA: characterization by high-performance affinity chromatography with immobilized albumin column. | 2010 | Mol Nutr Food Res | pmid:20013883 |
| Jun X et al. | Separation of major catechins from green tea by ultrahigh pressure extraction. | 2010 | Int J Pharm | pmid:19874878 |
| Iwasaki M et al. | Plasma tea polyphenol levels and subsequent risk of breast cancer among Japanese women: a nested case-control study. | 2010 | Breast Cancer Res. Treat. | pmid:20440552 |
| Anderson JC et al. | Anti-staphylococcal activity and β-lactam resistance attenuating capacity of structural analogues of (-)-epicatechin gallate. | 2011 | Bioorg. Med. Chem. Lett. | pmid:22030031 |
| Durgo K et al. | Genotoxic effects of green tea extract on human laryngeal carcinoma cells in vitro. | 2011 | Arh Hig Rada Toksikol | pmid:21705301 |
| Ramos S et al. | Dietary flavanols exert different effects on antioxidant defenses and apoptosis/proliferation in Caco-2 and SW480 colon cancer cells. | 2011 | Toxicol In Vitro | pmid:21945981 |
| RodrÃguez-Ramiro I et al. | Comparative effects of dietary flavanols on antioxidant defences and their response to oxidant-induced stress on Caco2 cells. | 2011 | Eur J Nutr | pmid:21046126 |
| Vyas S et al. | Potential O-acyl-substituted (-)-Epicatechin gallate prodrugs as inhibitors of DMBA/TPA-induced squamous cell carcinoma of skin in Swiss albino mice. | 2011 | Chem. Biodivers. | pmid:21480506 |
| Ferreira PG et al. | Stimulation of acidic reduction of nitrite to nitric oxide by soybean phenolics: possible relevance to gastrointestinal host defense. | 2011 | J. Agric. Food Chem. | pmid:21510708 |
| Cushnie TP and Lamb AJ | Recent advances in understanding the antibacterial properties of flavonoids. | 2011 | Int. J. Antimicrob. Agents | pmid:21514796 |
| Kürbitz C et al. | Epicatechin gallate and catechin gallate are superior to epigallocatechin gallate in growth suppression and anti-inflammatory activities in pancreatic tumor cells. | 2011 | Cancer Sci. | pmid:21241417 |
| Narukawa M et al. | Evaluation of the bitterness of green tea catechins by a cell-based assay with the human bitter taste receptor hTAS2R39. | 2011 | Biochem. Biophys. Res. Commun. | pmid:21272567 |
| Roth M et al. | Interactions of green tea catechins with organic anion-transporting polypeptides. | 2011 | Drug Metab. Dispos. | pmid:21278283 |
| Tayama Y et al. | Effect of tea beverages on aldehyde oxidase activity. | 2011 | Drug Metab. Pharmacokinet. | pmid:21084768 |
| Uekusa Y et al. | Interaction of epicatechin gallate with phospholipid membranes as revealed by solid-state NMR spectroscopy. | 2011 | Biochim. Biophys. Acta | pmid:21352801 |
| Zoechling A et al. | Red wine: a source of potent ligands for peroxisome proliferator-activated receptor γ. | 2011 | Food Funct | pmid:21773583 |
| Pan MH et al. | Multistage carcinogenesis process as molecular targets in cancer chemoprevention by epicatechin-3-gallate. | 2011 | Food Funct | pmid:21779554 |
| Li C et al. | Green tea polyphenols control dysregulated glutamate dehydrogenase in transgenic mice by hijacking the ADP activation site. | 2011 | J. Biol. Chem. | pmid:21813650 |
| Miyake T et al. | Analysis of the mechanism of inhibition of human matrix metalloproteinase 7 (MMP-7) activity by green tea catechins. | 2011 | Biosci. Biotechnol. Biochem. | pmid:21821933 |
| El-Hawary SA et al. | A profile of bioactive compounds of Rumex vesicarius L. | 2011 | J. Food Sci. | pmid:22417584 |
| Hu Y et al. | Bioactive components from the tea polyphenols influence on endogenous antioxidant defense system and modulate inflammatory cytokines after total-body irradiation in mice. | 2011 | Phytomedicine | pmid:21498061 |
| Erdogan S et al. | Pressurized liquid extraction of phenolic compounds from Anatolia propolis and their radical scavenging capacities. | 2011 | Food Chem. Toxicol. | pmid:21530603 |
| Chen Y et al. | Effect of girdling at various positions of 'Huang Zhi Xiang' tea tree (Camellia sinensis) on the contents of catechins and starch in fresh leaf. | 2011 | Plant Foods Hum Nutr | pmid:21523413 |
| Maruyama T et al. | Supplementation of green tea catechins in dentifrices suppresses gingival oxidative stress and periodontal inflammation. | 2011 | Arch. Oral Biol. | pmid:20869695 |
| Wu X et al. | Analysis of binding interaction between (-)-epigallocatechin (EGC) and β-lactoglobulin by multi-spectroscopic method. | 2011 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:21820944 |
| Ingólfsson HI et al. | Effects of green tea catechins on gramicidin channel function and inferred changes in bilayer properties. | 2011 | FEBS Lett. | pmid:21896274 |
| Zheng R et al. | A comparative reverse docking strategy to identify potential antineoplastic targets of tea functional components and binding mode. | 2011 | Int J Mol Sci | pmid:21954353 |
| Alvarez AL et al. | Bioactivity-guided fractionation of Phyllanthus orbicularis and identification of the principal anti HSV-2 compounds. | 2012 | Phytother Res | pmid:22318977 |
| Choudhary S et al. | Intervention of human breast cell carcinogenesis chronically induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine. | 2012 | Carcinogenesis | pmid:22307971 |
| Shen JM et al. | Chitosan-based luminescent/magnetic hybrid nanogels for insulin delivery, cell imaging, and antidiabetic research of dietary supplements. | 2012 | Int J Pharm | pmid:22342466 |
| Sato T et al. | Characterization of creaming precipitate of tea catechins and caffeine in aqueous solution. | 2012 | Chem. Pharm. Bull. | pmid:22976328 |
| Zhang QH et al. | Simultaneous determination of catechin, epicatechin and epicatechin gallate in rat plasma by LC-ESI-MS/MS for pharmacokinetic studies after oral administration of Cynomorium songaricum extract. | 2012 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:22153330 |
| Stadlbauer S et al. | A new synthetic strategy for catechin-class polyphenols: concise synthesis of (-)-epicatechin and its 3-O-gallate. | 2012 | Chem. Commun. (Camb.) | pmid:22790234 |
| Zhao Y et al. | Catechins containing a galloyl moiety as potential anti-HIV-1 compounds. | 2012 | Drug Discov. Today | pmid:22414543 |
| Kelman D and Wright AD | The importance of 1H-nuclear magnetic resonance spectroscopy for reference standard validation in analytical sciences. | 2012 | PLoS ONE | pmid:22848701 |
| Yuda N et al. | Polyphenols extracted from black tea (Camellia sinensis) residue by hot-compressed water and their inhibitory effect on pancreatic lipase in vitro. | 2012 | J. Food Sci. | pmid:23106349 |
| Tagashira T et al. | Influence of gallate and pyrogallol moieties on the intestinal absorption of (-)-epicatechin and (-)-epicatechin gallate. | 2012 | J. Food Sci. | pmid:22938538 |
| Sasaki T et al. | Green tea catechins increase the force of contraction in isolated guinea pig atrial muscle preparations by increasing the amplitude of intracellular Ca2+ concentration. | 2012 | J. Vet. Med. Sci. | pmid:22864409 |
| Kamihira-Ishijima M et al. | Inhibitory mechanism of pancreatic amyloid fibril formation: formation of the complex between tea catechins and the fragment of residues 22-27. | 2012 | Biochemistry | pmid:23205879 |
| Shrestha SP et al. | Glucuronidation and methylation of procyanidin dimers b2 and 3,3″-di-o-galloyl-b2 and corresponding monomers epicatechin and 3-o-galloyl-epicatechin in mouse liver. | 2012 | Pharm. Res. | pmid:22068277 |
| Luo ZM et al. | A new norisoprenoid and other compounds from Fuzhuan brick tea. | 2012 | Molecules | pmid:22430120 |
| Rathore K et al. | Green tea catechin intervention of reactive oxygen species-mediated ERK pathway activation and chronically induced breast cell carcinogenesis. | 2012 | Carcinogenesis | pmid:22045026 |
| Yin J et al. | Reduction of ferrylmyoglobin by theanine and green tea catechins. Importance of specific Acid catalysis. | 2013 | J. Agric. Food Chem. | pmid:23461366 |
| Cunha CA et al. | Green tea extract supplementation induces the lipolytic pathway, attenuates obesity, and reduces low-grade inflammation in mice fed a high-fat diet. | 2013 | Mediators Inflamm. | pmid:23431242 |
| Cordero-Herrera I et al. | Epicatechin gallate induces cell death via p53 activation and stimulation of p38 and JNK in human colon cancer SW480 cells. | 2013 | Nutr Cancer | pmid:23859040 |
| Sánchez-Tena S et al. | Epicatechin gallate impairs colon cancer cell metabolic productivity. | 2013 | J. Agric. Food Chem. | pmid:23594085 |
| Pandey KB et al. | Erythrocyte membrane transporters during human ageing: modulatory role of tea catechins. | 2013 | Clin. Exp. Pharmacol. Physiol. | pmid:23240554 |
| Du Q et al. | Scaling up of high-speed countercurrent chromatographic apparatus with three columns connected in series for rapid preparation of (-)-epicatechin. | 2013 | J Chromatogr A | pmid:23219478 |
| Wollmann N and Hofmann T | Compositional and sensory characterization of red wine polymers. | 2013 | J. Agric. Food Chem. | pmid:23387831 |
| Wu AZ et al. | Antiarrhythmic effects of (-)-epicatechin-3-gallate, a novel sodium channel agonist in cultured neonatal rat ventricular myocytes. | 2013 | Biochem. Pharmacol. | pmid:23116965 |
| Zhang Y et al. | Interaction of characteristic structural elements of persimmon tannin with Chinese cobra PLA2. | 2013 | Toxicon | pmid:23916601 |
| Bourassa P et al. | The effect of milk alpha-casein on the antioxidant activity of tea polyphenols. | 2013 | J. Photochem. Photobiol. B, Biol. | pmid:24001682 |
| Yamazaki T et al. | Activation of the hTAS2R14 human bitter-taste receptor by (-)-epigallocatechin gallate and (-)-epicatechin gallate. | 2013 | Biosci. Biotechnol. Biochem. | pmid:24018685 |
| Egert S et al. | Simultaneous ingestion of dietary proteins reduces the bioavailability of galloylated catechins from green tea in humans. | 2013 | Eur J Nutr | pmid:22366739 |
| Ly BT et al. | Inhibition of FLT3 expression by green tea catechins in FLT3 mutated-AML cells. | 2013 | PLoS ONE | pmid:23840454 |
| Trnková L et al. | Green tea catechins can bind and modify ERp57/PDIA3 activity. | 2013 | Biochim. Biophys. Acta | pmid:23671928 |
| Ghosh S et al. | (-)-Epicatechin gallate prevents alkali-salt mediated fibrillogenesis of hen egg white lysozyme. | 2013 | Int. J. Biol. Macromol. | pmid:23219698 |
| Park JS et al. | EGCG inhibits recepteur d'origine nantais expression by suppressing Egr-1 in gastric cancer cells. | 2013 | Int. J. Oncol. | pmid:23337910 |
| Krych J and Gebicka L | Catalase is inhibited by flavonoids. | 2013 | Int. J. Biol. Macromol. | pmid:23567286 |
| Chung JH et al. | Green tea formulations with vitamin C and xylitol on enhanced intestinal transport of green tea catechins. | 2013 | J. Food Sci. | pmid:23551173 |
| Li F et al. | Inhibitory effect of catechin-related compounds on renin activity. | 2013 | Biomed. Res. | pmid:23782751 |
| Qin R et al. | The combination of catechin and epicatechin callate from Fructus Crataegi potentiates beta-lactam antibiotics against methicillin-resistant staphylococcus aureus (MRSA) in vitro and in vivo. | 2013 | Int J Mol Sci | pmid:23325048 |
| Roman MC | Determination of catechins and caffeine in camillia sinensis raw materials, extracts, and dietary supplements by HPLC-uv: single-laboratory validation. | 2013 Sep-Oct | J AOAC Int | pmid:24282928 |
| Vogiatzoglou A et al. | Estimated dietary intakes and sources of flavanols in the German population (German National Nutrition Survey II). | 2014 | Eur J Nutr | pmid:23917449 |
| Yousaf S et al. | The role of green tea extract and powder in mitigating metabolic syndromes with special reference to hyperglycemia and hypercholesterolemia. | 2014 | Food Funct | pmid:24473227 |
| Narumi K et al. | Simultaneous detection of green tea catechins and gallic acid in human serum after ingestion of green tea tablets using ion-pair high-performance liquid chromatography with electrochemical detection. | 2014 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:24342507 |
| Byun MR et al. | (-)-Epicatechin gallate (ECG) stimulates osteoblast differentiation via Runt-related transcription factor 2 (RUNX2) and transcriptional coactivator with PDZ-binding motif (TAZ)-mediated transcriptional activation. | 2014 | J. Biol. Chem. | pmid:24515112 |
| Lakornwong W et al. | Chemical constituents from the roots of Leea thorelii Gagnep. | 2014 | Nat. Prod. Res. | pmid:24784484 |
| Yoshino S et al. | Effect of emulsification on the skin permeation and UV protection of catechin. | 2014 | Pharm Dev Technol | pmid:23639253 |
| Paulin S et al. | Surfactant-free purification of membrane protein complexes from bacteria: application to the staphylococcal penicillin-binding protein complex PBP2/PBP2a. | 2014 | Nanotechnology | pmid:24972373 |
| Tay PY et al. | Assessment of extraction parameters on antioxidant capacity, polyphenol content, epigallocatechin gallate (EGCG), epicatechin gallate (ECG) and iriflophenone 3-C-β-glucoside of agarwood (Aquilaria crassna) young leaves. | 2014 | Molecules | pmid:25153858 |
| Pal S et al. | Inhibition of catalase by tea catechins in free and cellular state: a biophysical approach. | 2014 | PLoS ONE | pmid:25025898 |
| Lee LS et al. | Quantitative analysis of major constituents in green tea with different plucking periods and their antioxidant activity. | 2014 | Molecules | pmid:24988187 |
| Roland WS et al. | 6-methoxyflavanones as bitter taste receptor blockers for hTAS2R39. | 2014 | PLoS ONE | pmid:24722342 |
| Stavniichuk R et al. | Peroxynitrite and protein nitration in the pathogenesis of diabetic peripheral neuropathy. | 2014 | Diabetes Metab. Res. Rev. | pmid:24687457 |
| Ge H et al. | Mechanistic studies for tri-targeted inhibition of enzymes involved in cholesterol biosynthesis by green tea polyphenols. | 2014 | Org. Biomol. Chem. | pmid:24879560 |
| Zhang Y et al. | [Assessment of inner filter effect corrections in fluorimetry of the interaction between polyphenols and proteins]. | 2014 | Guang Pu Xue Yu Guang Pu Fen Xi | pmid:24783545 |
| Siddique YH et al. | Effect of epicatechin gallate dietary supplementation on transgenic Drosophila model of Parkinson's disease. | 2014 | J Diet Suppl | pmid:24670116 |
| Peek J et al. | Identification of Novel Polyphenolic Inhibitors of Shikimate Dehydrogenase (AroE). | 2014 | J Biomol Screen | pmid:24632659 |
| Furlan AL et al. | Membrane lipids protected from oxidation by red wine tannins: a proton NMR study. | 2014 | Biochimie | pmid:25063276 |
| Lall N et al. | Extract from Ceratonia siliqua Exhibits Depigmentation Properties. | 2015 | Phytother Res | pmid:26201055 |
| Zhu W et al. | A-type ECG and EGCG dimers disturb the structure of 3T3-L1 cell membrane and strongly inhibit its differentiation by targeting peroxisome proliferator-activated receptor γ with miR-27 involved mechanism. | 2015 | J. Nutr. Biochem. | pmid:26145192 |
| Schmuch J et al. | Extract from Rumex acetosa L. for prophylaxis of periodontitis: inhibition of bacterial in vitro adhesion and of gingipains of Porphyromonas gingivalis by epicatechin-3-O-(4β→8)-epicatechin-3-O-gallate (procyanidin-B2-Di-gallate). | 2015 | PLoS ONE | pmid:25803708 |
| Chen L et al. | Bioactivity-guided fractionation of an antidiarrheal Chinese herb Rhodiola kirilowii (Regel) Maxim reveals (-)-epicatechin-3-gallate and (-)-epigallocatechin-3-gallate as inhibitors of cystic fibrosis transmembrane conductance regulator. | 2015 | PLoS ONE | pmid:25747701 |
| Kaneko YK et al. | Structure-dependent inhibitory effects of green tea catechins on insulin secretion from pancreatic β-cells. | 2015 | Biol. Pharm. Bull. | pmid:25757931 |