MeSH term | MeSH ID | Detail |
---|---|---|
Colonic Neoplasms | D003110 | 161 associated lipids |
Cicatrix | D002921 | 9 associated lipids |
Epicatechin-3-gallate is a lipid of Polyketides (PK) class. Epicatechin-3-gallate is associated with abnormalities such as Epilepsy and Megalencephaly. The involved functions are known as Docking, Drug Interactions, inhibitors, Oxidation and Inflammation Process. Epicatechin-3-gallate often locates in Solitary microtubule component of centriole or axonemal complex, Palmar surface, Glial and peritoneal. The associated genes with Epicatechin-3-gallate are Homologous Gene and TSC1 gene.
To understand associated biological information of Epicatechin-3-gallate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Epicatechin-3-gallate is suspected in Epilepsy, Megalencephaly and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Epicatechin-3-gallate
MeSH term | MeSH ID | Detail |
---|---|---|
Colonic Neoplasms | D003110 | 161 associated lipids |
Cicatrix | D002921 | 9 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Pan CY et al. | Enhancement of inward Ca(2+) currents in bovine chromaffin cells by green tea polyphenol extracts. | 2002 | Neurochem. Int. | pmid:11738479 |
Nakagawa T et al. | Protective activity of green tea against free radical- and glucose-mediated protein damage. | 2002 | J. Agric. Food Chem. | pmid:11929306 |
Amantana A et al. | Antimutagenic activity of selenium-enriched green tea toward the heterocyclic amine 2-amino-3-methylimidazo[4,5-f]quinoline. | 2002 | Biol Trace Elem Res | pmid:12008980 |
Sachinidis A et al. | Inhibition of the PDGF beta-receptor tyrosine phosphorylation and its downstream intracellular signal transduction pathway in rat and human vascular smooth muscle cells by different catechins. | 2002 | FASEB J. | pmid:12039871 |
Mochizuki M et al. | Kinetic analysis and mechanistic aspects of autoxidation of catechins. | 2002 | Biochim. Biophys. Acta | pmid:11853955 |
Caturla N et al. | The relationship between the antioxidant and the antibacterial properties of galloylated catechins and the structure of phospholipid model membranes. | 2003 | Free Radic. Biol. Med. | pmid:12633742 |
Vaidyanathan JB and Walle T | Cellular uptake and efflux of the tea flavonoid (-)epicatechin-3-gallate in the human intestinal cell line Caco-2. | 2003 | J. Pharmacol. Exp. Ther. | pmid:12970388 |
Chen L et al. | Tea catechins protect against lead-induced ROS formation, mitochondrial dysfunction, and calcium dysregulation in PC12 cells. | 2003 | Chem. Res. Toxicol. | pmid:12971804 |
Sakanaka S | A novel convenient process to obtain a raw decaffeinated tea polyphenol fraction using a lignocellulose column. | 2003 | J. Agric. Food Chem. | pmid:12720405 |
Takizawa Y et al. | Pharmacokinetics of (-)-epicatechin-3-O-gallate, an active component of Onpi-to, in rats. | 2003 | Biol. Pharm. Bull. | pmid:12736498 |
Morré DJ et al. | Tea catechin synergies in inhibition of cancer cell proliferation and of a cancer specific cell surface oxidase (ECTO-NOX). | 2003 | Pharmacol. Toxicol. | pmid:12753411 |
Kohri T et al. | Identification of metabolites of (-)-epicatechin gallate and their metabolic fate in the rat. | 2003 | J. Agric. Food Chem. | pmid:12926915 |
Konishi Y et al. | Tea polyphenols inhibit the transport of dietary phenolic acids mediated by the monocarboxylic acid transporter (MCT) in intestinal Caco-2 cell monolayers. | 2003 | J. Agric. Food Chem. | pmid:14640574 |
Ikeda I et al. | Heat-epimerized tea catechins rich in gallocatechin gallate and catechin gallate are more effective to inhibit cholesterol absorption than tea catechins rich in epigallocatechin gallate and epicatechin gallate. | 2003 | J. Agric. Food Chem. | pmid:14640575 |
Wang X et al. | The galloyl moiety of green tea catechins is the critical structural feature to inhibit fatty-acid synthase. | 2003 | Biochem. Pharmacol. | pmid:14599562 |
Goodin MG and Rosengren RJ | Epigallocatechin gallate modulates CYP450 isoforms in the female Swiss-Webster mouse. | 2003 | Toxicol. Sci. | pmid:14600287 |
Hayakawa F et al. | Prooxidative activities of tea catechins in the presence of Cu2+. | 2004 | Biosci. Biotechnol. Biochem. | pmid:15388955 |
Kapoor M et al. | Effects of epicatechin gallate on wound healing and scar formation in a full thickness incisional wound healing model in rats. | 2004 | Am. J. Pathol. | pmid:15215184 |
Zhou YD et al. | Hypoxia-inducible factor-1 activation by (-)-epicatechin gallate: potential adverse effects of cancer chemoprevention with high-dose green tea extracts. | 2004 | J. Nat. Prod. | pmid:15620252 |
Okamoto M et al. | Inhibitory effect of green tea catechins on cysteine proteinases in Porphyromonas gingivalis. | 2004 | Oral Microbiol. Immunol. | pmid:14871352 |