MeSH term | MeSH ID | Detail |
---|---|---|
Colonic Neoplasms | D003110 | 161 associated lipids |
Cicatrix | D002921 | 9 associated lipids |
Epicatechin-3-gallate is a lipid of Polyketides (PK) class. Epicatechin-3-gallate is associated with abnormalities such as Epilepsy and Megalencephaly. The involved functions are known as Docking, Drug Interactions, inhibitors, Oxidation and Inflammation Process. Epicatechin-3-gallate often locates in Solitary microtubule component of centriole or axonemal complex, Palmar surface, Glial and peritoneal. The associated genes with Epicatechin-3-gallate are Homologous Gene and TSC1 gene.
To understand associated biological information of Epicatechin-3-gallate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Epicatechin-3-gallate is suspected in Epilepsy, Megalencephaly and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Epicatechin-3-gallate
MeSH term | MeSH ID | Detail |
---|---|---|
Colonic Neoplasms | D003110 | 161 associated lipids |
Cicatrix | D002921 | 9 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Kobayashi K et al. | Strong Inhibition of Secretory Sphingomyelinase by Catechins, Particularly by (-)-Epicatechin 3-O-Gallate and (-)-3'-O-Methylepigallocatechin 3-O-Gallate. | 2016 | J. Nutr. Sci. Vitaminol. | pmid:27264097 |
Minoda K et al. | Influence of the galloyl moiety in tea catechins on binding affinity for human serum albumin. | 2010 | J. Nutr. Sci. Vitaminol. | pmid:21228505 |
Hayes CJ et al. | Synthesis and preliminary anticancer activity studies of C4 and C8-modified derivatives of catechin gallate (CG) and epicatechin gallate (ECG). | 2006 | J. Org. Chem. | pmid:17168588 |
Nakamura H et al. | Green tea catechin inhibits lipopolysaccharide-induced bone resorption in vivo. | 2010 | J. Periodont. Res. | pmid:19602116 |
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Yokozawa T et al. | (-)-Epicatechin 3-O-gallate ameliorates the damages related to peroxynitrite production by mechanisms distinct from those of other free radical inhibitors. | 2004 | J. Pharm. Pharmacol. | pmid:15005882 |
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Bourassa P et al. | The effect of milk alpha-casein on the antioxidant activity of tea polyphenols. | 2013 | J. Photochem. Photobiol. B, Biol. | pmid:24001682 |
Park JH et al. | Ambivalent role of gallated catechins in glucose tolerance in humans: a novel insight into non-absorbable gallated catechin-derived inhibitors of glucose absorption. | 2009 | J. Physiol. Pharmacol. | pmid:20065503 |
Sasaki T et al. | Green tea catechins increase the force of contraction in isolated guinea pig atrial muscle preparations by increasing the amplitude of intracellular Ca2+ concentration. | 2012 | J. Vet. Med. Sci. | pmid:22864409 |
Matsumoto N et al. | Inhibitory effects of tea catechins, black tea extract and oolong tea extract on hepatocarcinogenesis in rat. | 1996 | Jpn. J. Cancer Res. | pmid:8957060 |
Malik S et al. | Molecular mechanisms underlying attenuation of cisplatin-induced acute kidney injury by epicatechin gallate. | 2016 | Lab. Invest. | pmid:27239733 |
Shah S et al. | The polyphenol (-)-epicatechin gallate disrupts the secretion of virulence-related proteins by Staphylococcus aureus. | 2008 | Lett. Appl. Microbiol. | pmid:18069979 |
Annabi B et al. | Inhibition of HuR and MMP-9 expression in macrophage-differentiated HL-60 myeloid leukemia cells by green tea polyphenol EGCg. | 2007 | Leuk. Res. | pmid:17081606 |
Coyle CH et al. | Antioxidant effects of green tea and its polyphenols on bladder cells. | 2008 | Life Sci. | pmid:18544457 |
Zhang A et al. | Inhibitory effects of jasmine green tea epicatechin isomers on free radical-induced lysis of red blood cells. | 1997 | Life Sci. | pmid:9244364 |
Hirao K et al. | Tea catechins reduce inflammatory reactions via mitogen-activated protein kinase pathways in toll-like receptor 2 ligand-stimulated dental pulp cells. | 2010 | Life Sci. | pmid:20176036 |
Van Dyke K et al. | Green tea extract and its polyphenols markedly inhibit luminol-dependent chemiluminescence activated by peroxynitrite or SIN-1. | 2000 Jan-Feb | Luminescence | pmid:10660664 |
Ishizu T et al. | Diastereomeric difference of inclusion modes between (-)-epicatechin gallate, (-)-epigallocatechin gallate and (+)-gallocatechin gallate, with beta-cyclodextrin in aqueous solvent. | 2008 | Magn Reson Chem | pmid:18318450 |