| MeSH term | MeSH ID | Detail |
|---|---|---|
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Cicatrix | D002921 | 9 associated lipids |
Total
2
Epicatechin-3-gallate
Epicatechin-3-gallate is a lipid of Polyketides (PK) class. Epicatechin-3-gallate is associated with abnormalities such as Epilepsy and Megalencephaly. The involved functions are known as Docking, Drug Interactions, inhibitors, Oxidation and Inflammation Process. Epicatechin-3-gallate often locates in Solitary microtubule component of centriole or axonemal complex, Palmar surface, Glial and peritoneal. The associated genes with Epicatechin-3-gallate are Homologous Gene and TSC1 gene.
Cross Reference
Introduction
To understand associated biological information of Epicatechin-3-gallate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Epicatechin-3-gallate?
Epicatechin-3-gallate is suspected in Epilepsy, Megalencephaly and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Epicatechin-3-gallate
PubChem Associated disorders and diseases
What pathways are associated with Epicatechin-3-gallate
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Epicatechin-3-gallate?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Epicatechin-3-gallate?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Epicatechin-3-gallate?
There are no associated biomedical information in the current reference collection.
What genes are associated with Epicatechin-3-gallate?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Epicatechin-3-gallate?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Epicatechin-3-gallate
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Yuan B et al. | Extraction, identification, and quantification of antioxidant phenolics from hazelnut (Corylus avellana L.) shells. | 2018 | Food Chem | pmid:29120806 |
| Kfoury N et al. | Striking changes in tea metabolites due to elevational effects. | 2018 | Food Chem | pmid:29853384 |
| Peng J et al. | Separation and purification of four phenolic compounds from persimmon by high-speed counter-current chromatography. | 2018 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:29136554 |
| Kim JH et al. | Inhibitory activity of (-)-epicatechin-3,5-O-digallate on α-glucosidase and in silico analysis. | 2018 | Int. J. Biol. Macromol. | pmid:28958819 |
| Satsu H et al. | Suppressive effect of nobiletin and epicatechin gallate on fructose uptake in human intestinal epithelial Caco-2 cells. | 2018 | Biosci. Biotechnol. Biochem. | pmid:29191128 |
| Al-Sayed E and Abdel-Daim MM | Analgesic and anti-inflammatory activities of epicatechin gallate from Bauhinia hookeri. | 2018 | Drug Dev. Res. | pmid:29732583 |
| Park JE et al. | Quantitative Analysis of Four Catechins from Green Tea Extract in Human Plasma Using Ultra-Performance Liquid Chromatography-Tandem Mass Spectrometry for Pharmacokinetic Studies. | 2018 | Molecules | pmid:29690635 |
| Xu YQ et al. | Quantitative analyses of the bitterness and astringency of catechins from green tea. | 2018 | Food Chem | pmid:29655718 |
| Yang H et al. | The relative antioxidant activity and steric structure of green tea catechins - A kinetic approach. | 2018 | Food Chem | pmid:29622228 |
| Tian DD et al. | Identification of Intestinal UDP-Glucuronosyltransferase Inhibitors in Green Tea ( Using a Biochemometric Approach: Application to Raloxifene as a Test Drug via In Vitro to In Vivo Extrapolation. | 2018 | Drug Metab. Dispos. | pmid:29467215 |
| Stadlbauer S et al. | Impact of Green Tea Catechin ECG and Its Synthesized Fluorinated Analogue on Prostate Cancer Cells and Stimulated Immunocompetent Cells. | 2018 | Planta Med. | pmid:29466808 |
| Fujimaki T et al. | Isolation of proanthocyanidins from red wine, and their inhibitory effects on melanin synthesis in vitro. | 2018 | Food Chem | pmid:29329871 |
| Mukherjee S et al. | Liposomal TriCurin, A Synergistic Combination of Curcumin, Epicatechin Gallate and Resveratrol, Repolarizes Tumor-Associated Microglia/Macrophages, and Eliminates Glioblastoma (GBM) and GBM Stem Cells. | 2018 | Molecules | pmid:29346317 |
| Lei S et al. | Effective synthesis of theaflavin-3,3'-digallate with epigallocatechin-3-O-gallate and epicatechin gallate as substrates by using immobilized pear polyphenol oxidase. | 2017 | Int. J. Biol. Macromol. | pmid:27780760 |
| Dhanani T et al. | Extraction optimization of gallic acid, (+)-catechin, procyanidin-B2, (-)-epicatechin, (-)-epigallocatechin gallate, and (-)-epicatechin gallate: their simultaneous identification and quantification in Saraca asoca. | 2017 | J Food Drug Anal | pmid:28911654 |
| Koch W et al. | Catechin Composition and Antioxidant Activity of Black Teas in Relation to Brewing Time. | 2017 | J AOAC Int | pmid:28707612 |
| Guo YJ et al. | An integrated antioxidant activity fingerprint for commercial teas based on their capacities to scavenge reactive oxygen species. | 2017 | Food Chem | pmid:28764047 |
| Zhu W et al. | A-type ECG and EGCG dimers inhibit 3T3-L1 differentiation by binding to cholesterol in lipid rafts. | 2017 | J. Nutr. Biochem. | pmid:28772148 |
| Zhang QA et al. | Effect of ultrasound on the interaction between (-)-epicatechin gallate and bovine serum albumin in a model wine. | 2017 | Ultrason Sonochem | pmid:28427650 |
| Karas D et al. | Galloylation of polyphenols alters their biological activity. | 2017 | Food Chem. Toxicol. | pmid:28428085 |
| Chen JH et al. | Autophagic effects of Hibiscus sabdariffa leaf polyphenols and epicatechin gallate (ECG) against oxidized LDL-induced injury of human endothelial cells. | 2017 | Eur J Nutr | pmid:27318926 |
| Zinellu A et al. | N- and S-homocysteinylation reduce the binding of human serum albumin to catechins. | 2017 | Eur J Nutr | pmid:26658763 |
| Cui L et al. | Extraction of Epigallocatechin Gallate and Epicatechin Gallate from Tea Leaves Using β-Cyclodextrin. | 2017 | J. Food Sci. | pmid:28071811 |
| Fathima A and Rao JR | Selective toxicity of Catechin-a natural flavonoid towards bacteria. | 2016 | Appl. Microbiol. Biotechnol. | pmid:27052380 |
| Zhang YN et al. | Improving the sweet aftertaste of green tea infusion with tannase. | 2016 | Food Chem | pmid:26304374 |
| Takechi R et al. | Elevated plasma and urinary concentrations of green tea catechins associated with improved plasma lipid profile in healthy Japanese women. | 2016 | Nutr Res | pmid:26923508 |
| Chiou YS et al. | Directly interact with Keap1 and LPS is involved in the anti-inflammatory mechanisms of (-)-epicatechin-3-gallate in LPS-induced macrophages and endotoxemia. | 2016 | Free Radic. Biol. Med. | pmid:26878775 |
| Godsey J and Grundmann O | Review of Various Herbal Supplements as Complementary Treatments for Oral Cancer. | 2016 | J Diet Suppl | pmid:26863913 |
| Farhan M et al. | Mobilization of Nuclear Copper by Green Tea Polyphenol Epicatechin-3-Gallate and Subsequent Prooxidant Breakage of Cellular DNA: Implications for Cancer Chemotherapy. | 2016 | Int J Mol Sci | pmid:28035959 |
| Kobayashi K et al. | Strong Inhibition of Secretory Sphingomyelinase by Catechins, Particularly by (-)-Epicatechin 3-O-Gallate and (-)-3'-O-Methylepigallocatechin 3-O-Gallate. | 2016 | J. Nutr. Sci. Vitaminol. | pmid:27264097 |
| Malik S et al. | Molecular mechanisms underlying attenuation of cisplatin-induced acute kidney injury by epicatechin gallate. | 2016 | Lab. Invest. | pmid:27239733 |
| Wein S et al. | Systemic Absorption of Catechins after Intraruminal or Intraduodenal Application of a Green Tea Extract in Cows. | 2016 | PLoS ONE | pmid:27427946 |
| Huang SF et al. | Epicatechin-3-gallate reverses TGF-β1-induced epithelial-to-mesenchymal transition and inhibits cell invasion and protease activities in human lung cancer cells. | 2016 | Food Chem. Toxicol. | pmid:27224248 |
| Abourashed EA et al. | Content Variation of Catechin Markers, Total Phenolics and Caffeine in Green Tea Dietary Supplements. | 2016 | J Diet Suppl | pmid:25299974 |
| Li Q et al. | Separation and characterization of polyphenolics from underutilized byproducts of fruit production (Choerospondias axillaris peels): inhibitory activity of proanthocyanidins against glycolysis enzymes. | 2015 | Food Funct | pmid:26442714 |
| Chiu CT et al. | Hibiscus sabdariffa leaf polyphenolic extract induces human melanoma cell death, apoptosis, and autophagy. | 2015 | J. Food Sci. | pmid:25694272 |
| Lall N et al. | Extract from Ceratonia siliqua Exhibits Depigmentation Properties. | 2015 | Phytother Res | pmid:26201055 |
| Grases F et al. | Effect of consuming a grape seed supplement with abundant phenolic compounds on the oxidative status of healthy human volunteers. | 2015 | Nutr J | pmid:26353756 |
| Rosado H et al. | Impact of the β-Lactam Resistance Modifier (-)-Epicatechin Gallate on the Non-Random Distribution of Phospholipids across the Cytoplasmic Membrane of Staphylococcus aureus. | 2015 | Int J Mol Sci | pmid:26213914 |
| Zhu W et al. | A-type ECG and EGCG dimers disturb the structure of 3T3-L1 cell membrane and strongly inhibit its differentiation by targeting peroxisome proliferator-activated receptor γ with miR-27 involved mechanism. | 2015 | J. Nutr. Biochem. | pmid:26145192 |
| Zhang B et al. | Inflammatory mechanisms contribute to the neurological manifestations of tuberous sclerosis complex. | 2015 | Neurobiol. Dis. | pmid:26003087 |
| Liu Y et al. | Molecular weight and galloylation affect grape seed extract constituents' ability to cross-link dentin collagen in clinically relevant time. | 2015 | Dent Mater | pmid:25958268 |
| Schmuch J et al. | Extract from Rumex acetosa L. for prophylaxis of periodontitis: inhibition of bacterial in vitro adhesion and of gingipains of Porphyromonas gingivalis by epicatechin-3-O-(4β→8)-epicatechin-3-O-gallate (procyanidin-B2-Di-gallate). | 2015 | PLoS ONE | pmid:25803708 |
| Chen L et al. | Bioactivity-guided fractionation of an antidiarrheal Chinese herb Rhodiola kirilowii (Regel) Maxim reveals (-)-epicatechin-3-gallate and (-)-epigallocatechin-3-gallate as inhibitors of cystic fibrosis transmembrane conductance regulator. | 2015 | PLoS ONE | pmid:25747701 |
| Barr JT et al. | Inhibition of human aldehyde oxidase activity by diet-derived constituents: structural influence, enzyme-ligand interactions, and clinical relevance. | 2015 | Drug Metab. Dispos. | pmid:25326286 |
| Cai Y et al. | (-)-Epicatechin-3-gallate (a polyphenol from green tea) potentiates doxorubicin-induced apoptosis in H9C2 cardiomyocytes. | 2015 | Biotechnol. Lett. | pmid:26063620 |
| Nakanishi T et al. | Catechins inhibit vascular endothelial growth factor production and cyclooxygenase-2 expression in human dental pulp cells. | 2015 | Int Endod J | pmid:24847951 |
| Miao M et al. | Interaction mechanism between green tea extract and human α-amylase for reducing starch digestion. | 2015 | Food Chem | pmid:25976786 |
| Kaneko YK et al. | Structure-dependent inhibitory effects of green tea catechins on insulin secretion from pancreatic β-cells. | 2015 | Biol. Pharm. Bull. | pmid:25757931 |
| Müller P and Downard KM | Catechin inhibition of influenza neuraminidase and its molecular basis with mass spectrometry. | 2015 | J Pharm Biomed Anal | pmid:25910046 |