Epicatechin-3-gallate

Epicatechin-3-gallate is a lipid of Polyketides (PK) class. Epicatechin-3-gallate is associated with abnormalities such as Epilepsy and Megalencephaly. The involved functions are known as Docking, Drug Interactions, inhibitors, Oxidation and Inflammation Process. Epicatechin-3-gallate often locates in Solitary microtubule component of centriole or axonemal complex, Palmar surface, Glial and peritoneal. The associated genes with Epicatechin-3-gallate are Homologous Gene and TSC1 gene.

Cross Reference

Introduction

To understand associated biological information of Epicatechin-3-gallate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Epicatechin-3-gallate?

Epicatechin-3-gallate is suspected in Epilepsy, Megalencephaly and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Epicatechin-3-gallate

MeSH term MeSH ID Detail
Colonic Neoplasms D003110 161 associated lipids
Cicatrix D002921 9 associated lipids
Total 2

PubChem Associated disorders and diseases

What pathways are associated with Epicatechin-3-gallate

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Epicatechin-3-gallate?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Epicatechin-3-gallate?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Epicatechin-3-gallate?

There are no associated biomedical information in the current reference collection.

What genes are associated with Epicatechin-3-gallate?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Epicatechin-3-gallate?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Epicatechin-3-gallate

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Authors Title Published Journal PubMed Link
Coyle CH et al. Antioxidant effects of green tea and its polyphenols on bladder cells. 2008 Life Sci. pmid:18544457
Kawai Y et al. (-)-Epicatechin gallate accumulates in foamy macrophages in human atherosclerotic aorta: implication in the anti-atherosclerotic actions of tea catechins. 2008 Biochem. Biophys. Res. Commun. pmid:18657514
Kadowaki M et al. Presence or absence of a gallate moiety on catechins affects their cellular transport. 2008 J. Pharm. Pharmacol. pmid:18718123
Fu T et al. Simultaneous determination of the major active components of tea polyphenols in rat plasma by a simple and specific HPLC assay. 2008 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:18922746
Wang JS et al. Validation of green tea polyphenol biomarkers in a phase II human intervention trial. 2008 Food Chem. Toxicol. pmid:17888558
Li D et al. Identification of a PKCepsilon-dependent regulation of myocardial contraction by epicatechin-3-gallate. 2008 Am. J. Physiol. Heart Circ. Physiol. pmid:17951366
Shah S et al. The polyphenol (-)-epicatechin gallate disrupts the secretion of virulence-related proteins by Staphylococcus aureus. 2008 Lett. Appl. Microbiol. pmid:18069979
Green RJ et al. Common tea formulations modulate in vitro digestive recovery of green tea catechins. 2007 Mol Nutr Food Res pmid:17688297
Saito ST et al. Characterization of the constituents and antioxidant activity of Brazilian green tea (Camellia sinensis var. assamica IAC-259 cultivar) extracts. 2007 J. Agric. Food Chem. pmid:17937477
Mata-Bilbao Mde L et al. A new LC/MS/MS rapid and sensitive method for the determination of green tea catechins and their metabolites in biological samples. 2007 J. Agric. Food Chem. pmid:17902624
Uekusa Y et al. Dynamic behavior of tea catechins interacting with lipid membranes as determined by NMR spectroscopy. 2007 J. Agric. Food Chem. pmid:17966973
Noda Y and Peterson DG Structure-reactivity relationships of flavan-3-ols on product generation in aqueous glucose/glycine model systems. 2007 J. Agric. Food Chem. pmid:17394338
Thephinlap C et al. Epigallocatechin-3-gallate and epicatechin-3-gallate from green tea decrease plasma non-transferrin bound iron and erythrocyte oxidative stress. 2007 Med Chem pmid:17504202
Kyle JA et al. Effects of infusion time and addition of milk on content and absorption of polyphenols from black tea. 2007 J. Agric. Food Chem. pmid:17489604
Landis-Piwowar KR et al. Methylation suppresses the proteasome-inhibitory function of green tea polyphenols. 2007 J. Cell. Physiol. pmid:17477351
Cheng KW et al. Inhibitory activities of dietary phenolic compounds on heterocyclic amine formation in both chemical model system and beef patties. 2007 Mol Nutr Food Res pmid:17628877
Kusano R et al. Structures of epicatechin gallate trimer and tetramer produced by enzymatic oxidation. 2007 Chem. Pharm. Bull. pmid:18057757
Nishimuta H et al. Inhibitory effects of various beverages on human recombinant sulfotransferase isoforms SULT1A1 and SULT1A3. 2007 Biopharm Drug Dispos pmid:17876860
Lo HM et al. Tea polyphenols inhibit rat vascular smooth muscle cell adhesion and migration on collagen and laminin via interference with cell-ECM interaction. 2007 J. Biomed. Sci. pmid:17436062
Neilson AP et al. Catechin degradation with concurrent formation of homo- and heterocatechin dimers during in vitro digestion. 2007 J. Agric. Food Chem. pmid:17924707