| MeSH term | MeSH ID | Detail |
|---|---|---|
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Cicatrix | D002921 | 9 associated lipids |
Total
2
Epicatechin-3-gallate
Epicatechin-3-gallate is a lipid of Polyketides (PK) class. Epicatechin-3-gallate is associated with abnormalities such as Epilepsy and Megalencephaly. The involved functions are known as Docking, Drug Interactions, inhibitors, Oxidation and Inflammation Process. Epicatechin-3-gallate often locates in Solitary microtubule component of centriole or axonemal complex, Palmar surface, Glial and peritoneal. The associated genes with Epicatechin-3-gallate are Homologous Gene and TSC1 gene.
Cross Reference
Introduction
To understand associated biological information of Epicatechin-3-gallate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Epicatechin-3-gallate?
Epicatechin-3-gallate is suspected in Epilepsy, Megalencephaly and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Epicatechin-3-gallate
PubChem Associated disorders and diseases
What pathways are associated with Epicatechin-3-gallate
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Epicatechin-3-gallate?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Epicatechin-3-gallate?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Epicatechin-3-gallate?
There are no associated biomedical information in the current reference collection.
What genes are associated with Epicatechin-3-gallate?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Epicatechin-3-gallate?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Epicatechin-3-gallate
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Choudhary S et al. | Intervention of human breast cell carcinogenesis chronically induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine. | 2012 | Carcinogenesis | pmid:22307971 |
| Kelman D and Wright AD | The importance of 1H-nuclear magnetic resonance spectroscopy for reference standard validation in analytical sciences. | 2012 | PLoS ONE | pmid:22848701 |
| Sasaki T et al. | Green tea catechins increase the force of contraction in isolated guinea pig atrial muscle preparations by increasing the amplitude of intracellular Ca2+ concentration. | 2012 | J. Vet. Med. Sci. | pmid:22864409 |
| Shrestha SP et al. | Glucuronidation and methylation of procyanidin dimers b2 and 3,3″-di-o-galloyl-b2 and corresponding monomers epicatechin and 3-o-galloyl-epicatechin in mouse liver. | 2012 | Pharm. Res. | pmid:22068277 |
| Luo ZM et al. | A new norisoprenoid and other compounds from Fuzhuan brick tea. | 2012 | Molecules | pmid:22430120 |
| Rathore K et al. | Green tea catechin intervention of reactive oxygen species-mediated ERK pathway activation and chronically induced breast cell carcinogenesis. | 2012 | Carcinogenesis | pmid:22045026 |
| Anderson JC et al. | Anti-staphylococcal activity and β-lactam resistance attenuating capacity of structural analogues of (-)-epicatechin gallate. | 2011 | Bioorg. Med. Chem. Lett. | pmid:22030031 |
| Durgo K et al. | Genotoxic effects of green tea extract on human laryngeal carcinoma cells in vitro. | 2011 | Arh Hig Rada Toksikol | pmid:21705301 |
| Ramos S et al. | Dietary flavanols exert different effects on antioxidant defenses and apoptosis/proliferation in Caco-2 and SW480 colon cancer cells. | 2011 | Toxicol In Vitro | pmid:21945981 |
| RodrÃguez-Ramiro I et al. | Comparative effects of dietary flavanols on antioxidant defences and their response to oxidant-induced stress on Caco2 cells. | 2011 | Eur J Nutr | pmid:21046126 |
| Vyas S et al. | Potential O-acyl-substituted (-)-Epicatechin gallate prodrugs as inhibitors of DMBA/TPA-induced squamous cell carcinoma of skin in Swiss albino mice. | 2011 | Chem. Biodivers. | pmid:21480506 |
| Ferreira PG et al. | Stimulation of acidic reduction of nitrite to nitric oxide by soybean phenolics: possible relevance to gastrointestinal host defense. | 2011 | J. Agric. Food Chem. | pmid:21510708 |
| Cushnie TP and Lamb AJ | Recent advances in understanding the antibacterial properties of flavonoids. | 2011 | Int. J. Antimicrob. Agents | pmid:21514796 |
| Kürbitz C et al. | Epicatechin gallate and catechin gallate are superior to epigallocatechin gallate in growth suppression and anti-inflammatory activities in pancreatic tumor cells. | 2011 | Cancer Sci. | pmid:21241417 |
| Narukawa M et al. | Evaluation of the bitterness of green tea catechins by a cell-based assay with the human bitter taste receptor hTAS2R39. | 2011 | Biochem. Biophys. Res. Commun. | pmid:21272567 |
| Roth M et al. | Interactions of green tea catechins with organic anion-transporting polypeptides. | 2011 | Drug Metab. Dispos. | pmid:21278283 |
| Tayama Y et al. | Effect of tea beverages on aldehyde oxidase activity. | 2011 | Drug Metab. Pharmacokinet. | pmid:21084768 |
| Uekusa Y et al. | Interaction of epicatechin gallate with phospholipid membranes as revealed by solid-state NMR spectroscopy. | 2011 | Biochim. Biophys. Acta | pmid:21352801 |
| Zoechling A et al. | Red wine: a source of potent ligands for peroxisome proliferator-activated receptor γ. | 2011 | Food Funct | pmid:21773583 |
| Pan MH et al. | Multistage carcinogenesis process as molecular targets in cancer chemoprevention by epicatechin-3-gallate. | 2011 | Food Funct | pmid:21779554 |
| Li C et al. | Green tea polyphenols control dysregulated glutamate dehydrogenase in transgenic mice by hijacking the ADP activation site. | 2011 | J. Biol. Chem. | pmid:21813650 |
| Miyake T et al. | Analysis of the mechanism of inhibition of human matrix metalloproteinase 7 (MMP-7) activity by green tea catechins. | 2011 | Biosci. Biotechnol. Biochem. | pmid:21821933 |
| El-Hawary SA et al. | A profile of bioactive compounds of Rumex vesicarius L. | 2011 | J. Food Sci. | pmid:22417584 |
| Hu Y et al. | Bioactive components from the tea polyphenols influence on endogenous antioxidant defense system and modulate inflammatory cytokines after total-body irradiation in mice. | 2011 | Phytomedicine | pmid:21498061 |
| Erdogan S et al. | Pressurized liquid extraction of phenolic compounds from Anatolia propolis and their radical scavenging capacities. | 2011 | Food Chem. Toxicol. | pmid:21530603 |
| Chen Y et al. | Effect of girdling at various positions of 'Huang Zhi Xiang' tea tree (Camellia sinensis) on the contents of catechins and starch in fresh leaf. | 2011 | Plant Foods Hum Nutr | pmid:21523413 |
| Maruyama T et al. | Supplementation of green tea catechins in dentifrices suppresses gingival oxidative stress and periodontal inflammation. | 2011 | Arch. Oral Biol. | pmid:20869695 |
| Wu X et al. | Analysis of binding interaction between (-)-epigallocatechin (EGC) and β-lactoglobulin by multi-spectroscopic method. | 2011 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:21820944 |
| Ingólfsson HI et al. | Effects of green tea catechins on gramicidin channel function and inferred changes in bilayer properties. | 2011 | FEBS Lett. | pmid:21896274 |
| Zheng R et al. | A comparative reverse docking strategy to identify potential antineoplastic targets of tea functional components and binding mode. | 2011 | Int J Mol Sci | pmid:21954353 |
| Tu HC et al. | Epicatechin gallate decreases the viability and subsequent embryonic development of mouse blastocysts. | 2010 | Taiwan J Obstet Gynecol | pmid:20708524 |
| Abib RT et al. | Genoprotective effects of the green tea-derived polyphenol/epicatechin gallate in C6 astroglial cells. | 2010 | J Med Food | pmid:20828315 |
| Schantz M et al. | Metabolism of green tea catechins by the human small intestine. | 2010 | Biotechnol J | pmid:20931601 |
| Sukhthankar M et al. | A potential proliferative gene, NUDT6, is down-regulated by green tea catechins at the posttranscriptional level. | 2010 | J. Nutr. Biochem. | pmid:19157820 |
| Hosokawa Y et al. | Catechins inhibit CXCL10 production from oncostatin M-stimulated human gingival fibroblasts. | 2010 | J. Nutr. Biochem. | pmid:19616927 |
| Kim HJ et al. | Epicatechin gallate suppresses oxidative stress-induced MUC5AC overexpression by interaction with epidermal growth factor receptor. | 2010 | Am. J. Respir. Cell Mol. Biol. | pmid:19855084 |
| Hosokawa Y et al. | Tea polyphenols inhibit IL-6 production in tumor necrosis factor superfamily 14-stimulated human gingival fibroblasts. | 2010 | Mol Nutr Food Res | pmid:20461739 |
| Nakanishi T et al. | Anti-inflammatory effect of catechin on cultured human dental pulp cells affected by bacteria-derived factors. | 2010 | Eur. J. Oral Sci. | pmid:20487003 |
| Duhon D et al. | The polyphenol epigallocatechin-3-gallate affects lipid rafts to block activation of the c-Met receptor in prostate cancer cells. | 2010 | Mol. Carcinog. | pmid:20623641 |
| Bernal P et al. | Insertion of epicatechin gallate into the cytoplasmic membrane of methicillin-resistant Staphylococcus aureus disrupts penicillin-binding protein (PBP) 2a-mediated beta-lactam resistance by delocalizing PBP2. | 2010 | J. Biol. Chem. | pmid:20516078 |
| Jackson JK et al. | The inhibition of collagenase induced degradation of collagen by the galloyl-containing polyphenols tannic acid, epigallocatechin gallate and epicatechin gallate. | 2010 | J Mater Sci Mater Med | pmid:20162329 |
| Hirao K et al. | Tea catechins reduce inflammatory reactions via mitogen-activated protein kinase pathways in toll-like receptor 2 ligand-stimulated dental pulp cells. | 2010 | Life Sci. | pmid:20176036 |
| Ferrer-Gallego R et al. | Statistical correlation between flavanolic composition, colour and sensorial parameters in grape seed during ripening. | 2010 | Anal. Chim. Acta | pmid:20103139 |
| Soe WM et al. | In vitro drug interactions of gallates with antibiotics in Staphylococcus Aureus. | 2010 | Front Biosci (Elite Ed) | pmid:20036910 |
| Jiang F et al. | The evaluation of catechins that contain a galloyl moiety as potential HIV-1 integrase inhibitors. | 2010 | Clin. Immunol. | pmid:20832370 |
| Ziaedini A et al. | Extraction of antioxidants and caffeine from green tea (Camelia sinensis) leaves: kinetics and modeling. | 2010 | Food Sci Technol Int | pmid:21339166 |
| Minoda K et al. | Influence of the galloyl moiety in tea catechins on binding affinity for human serum albumin. | 2010 | J. Nutr. Sci. Vitaminol. | pmid:21228505 |
| Schmidt CA et al. | Catechin derivatives from Parapiptadenia rigida with in vitro wound-healing properties. | 2010 | J. Nat. Prod. | pmid:21080642 |
| Nakamura H et al. | Green tea catechin inhibits lipopolysaccharide-induced bone resorption in vivo. | 2010 | J. Periodont. Res. | pmid:19602116 |
| Cao P et al. | Effect of green tea catechins and hydrolyzable tannins on benzo[a]pyrene-induced DNA adducts and structure-activity relationship. | 2010 | Chem. Res. Toxicol. | pmid:20218540 |
| Korte G et al. | Tea catechins' affinity for human cannabinoid receptors. | 2010 | Phytomedicine | pmid:19897346 |
| Ishii T et al. | Binding affinity of tea catechins for HSA: characterization by high-performance affinity chromatography with immobilized albumin column. | 2010 | Mol Nutr Food Res | pmid:20013883 |
| Jun X et al. | Separation of major catechins from green tea by ultrahigh pressure extraction. | 2010 | Int J Pharm | pmid:19874878 |
| Iwasaki M et al. | Plasma tea polyphenol levels and subsequent risk of breast cancer among Japanese women: a nested case-control study. | 2010 | Breast Cancer Res. Treat. | pmid:20440552 |
| Feng W et al. | Green tea catechins are potent sensitizers of ryanodine receptor type 1 (RyR1). | 2010 | Biochem. Pharmacol. | pmid:20471964 |
| Manna S et al. | Tea polyphenols can restrict benzo[a]pyrene-induced lung carcinogenesis by altered expression of p53-associated genes and H-ras, c-myc and cyclin D1. | 2009 | J. Nutr. Biochem. | pmid:18656336 |
| Hemdan DI et al. | Polyphenols prevent clinorotation-induced expression of atrogenes in mouse C2C12 skeletal myotubes. | 2009 | J. Med. Invest. | pmid:19262011 |
| Maurya PK and Rizvi SI | Protective role of tea catechins on erythrocytes subjected to oxidative stress during human aging. | 2009 | Nat. Prod. Res. | pmid:18846469 |
| Bernal P et al. | Disruption of D-alanyl esterification of Staphylococcus aureus cell wall teichoic acid by the {beta}-lactam resistance modifier (-)-epicatechin gallate. | 2009 | J. Antimicrob. Chemother. | pmid:19307172 |
| Appeldoorn MM et al. | Some phenolic compounds increase the nitric oxide level in endothelial cells in vitro. | 2009 | J. Agric. Food Chem. | pmid:19722703 |
| Jumtee K et al. | Fast GC-FID based metabolic fingerprinting of Japanese green tea leaf for its quality ranking prediction. | 2009 | J Sep Sci | pmid:19569110 |
| Hosokawa Y et al. | Catechins inhibit CCL20 production in IL-17A-stimulated human gingival fibroblasts. | 2009 | Cell. Physiol. Biochem. | pmid:19910679 |
| Kwak H et al. | Flavonoids inhibit the AU-rich element binding of HuC. | 2009 | BMB Rep | pmid:19192392 |
| Ishii T et al. | Catechol type polyphenol is a potential modifier of protein sulfhydryls: development and application of a new probe for understanding the dietary polyphenol actions. | 2009 | Chem. Res. Toxicol. | pmid:19743802 |
| Ku HC et al. | Green tea (-)-epigallocatechin gallate inhibits insulin stimulation of 3T3-L1 preadipocyte mitogenesis via the 67-kDa laminin receptor pathway. | 2009 | Am. J. Physiol., Cell Physiol. | pmid:19176763 |
| Stalmach A et al. | Absorption, metabolism and excretion of Choladi green tea flavan-3-ols by humans. | 2009 | Mol Nutr Food Res | pmid:18979506 |
| Ochiai H et al. | Epigallocatechin-3-gallate is an inhibitor of Na+, K(+)-ATPase by favoring the E1 conformation. | 2009 | Biochem. Pharmacol. | pmid:19539611 |
| Severino JF et al. | Free radicals generated during oxidation of green tea polyphenols: electron paramagnetic resonance spectroscopy combined with density functional theory calculations. | 2009 | Free Radic. Biol. Med. | pmid:19439236 |
| Liu J et al. | Borate complexation-assisted field-enhanced sample injection for on-line preconcentration of cis-diol-containing compounds in capillary electrophoresis. | 2009 | Talanta | pmid:19836518 |
| Park JH et al. | Ambivalent role of gallated catechins in glucose tolerance in humans: a novel insight into non-absorbable gallated catechin-derived inhibitors of glucose absorption. | 2009 | J. Physiol. Pharmacol. | pmid:20065503 |
| Liu TT and Yang TS | Effects of water-soluble natural antioxidants on photosensitized oxidation of conjugated linoleic acid in an oil-in-water emulsion system. | 2008 | J. Food Sci. | pmid:18460119 |
| Coyle CH et al. | Antioxidant effects of green tea and its polyphenols on bladder cells. | 2008 | Life Sci. | pmid:18544457 |
| Kawai Y et al. | (-)-Epicatechin gallate accumulates in foamy macrophages in human atherosclerotic aorta: implication in the anti-atherosclerotic actions of tea catechins. | 2008 | Biochem. Biophys. Res. Commun. | pmid:18657514 |
| Kadowaki M et al. | Presence or absence of a gallate moiety on catechins affects their cellular transport. | 2008 | J. Pharm. Pharmacol. | pmid:18718123 |
| Kawai Y et al. | Galloylated catechins as potent inhibitors of hypochlorous acid-induced DNA damage. | 2008 | Chem. Res. Toxicol. | pmid:18512968 |
| Dai F et al. | Antioxidant synergism of green tea polyphenols with alpha-tocopherol and L-ascorbic acid in SDS micelles. | 2008 | Biochimie | pmid:18554517 |
| Fu T et al. | Simultaneous determination of the major active components of tea polyphenols in rat plasma by a simple and specific HPLC assay. | 2008 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:18922746 |
| Wang JS et al. | Validation of green tea polyphenol biomarkers in a phase II human intervention trial. | 2008 | Food Chem. Toxicol. | pmid:17888558 |
| Li D et al. | Identification of a PKCepsilon-dependent regulation of myocardial contraction by epicatechin-3-gallate. | 2008 | Am. J. Physiol. Heart Circ. Physiol. | pmid:17951366 |
| Abib RT et al. | Epicatechin gallate increases glutamate uptake and S100B secretion in C6 cell lineage. | 2008 | Mol. Cell. Biochem. | pmid:18066651 |
| Shah S et al. | The polyphenol (-)-epicatechin gallate disrupts the secretion of virulence-related proteins by Staphylococcus aureus. | 2008 | Lett. Appl. Microbiol. | pmid:18069979 |
| Mata-Bilbao Mde L et al. | Absorption and pharmacokinetics of green tea catechins in beagles. | 2008 | Br. J. Nutr. | pmid:18205995 |
| Ishizu T et al. | Diastereomeric difference of inclusion modes between (-)-epicatechin gallate, (-)-epigallocatechin gallate and (+)-gallocatechin gallate, with beta-cyclodextrin in aqueous solvent. | 2008 | Magn Reson Chem | pmid:18318450 |
| Mukai D et al. | Potential anthelmintics: polyphenols from the tea plant Camellia sinensis L. are lethally toxic to Caenorhabditis elegans. | 2008 | J Nat Med | pmid:18404315 |
| Fujimura Y et al. | The impact of the 67kDa laminin receptor on both cell-surface binding and anti-allergic action of tea catechins. | 2008 | Arch. Biochem. Biophys. | pmid:18358230 |
| Mitani S et al. | Stopped-flow kinetic study of the aroxyl radical-scavenging action of catechins and vitamin C in ethanol and micellar solutions. | 2008 | J. Agric. Food Chem. | pmid:18500808 |
| Ghosh KS et al. | Studies on the interaction of copper complexes of (-)-epicatechin gallate and (-)-epigallocatechin gallate with calf thymus DNA. | 2008 | J. Inorg. Biochem. | pmid:18541305 |
| Lin CL et al. | Theaflavins attenuate hepatic lipid accumulation through activating AMPK in human HepG2 cells. | 2007 | J. Lipid Res. | pmid:17720960 |
| Saito ST et al. | Characterization of the constituents and antioxidant activity of Brazilian green tea (Camellia sinensis var. assamica IAC-259 cultivar) extracts. | 2007 | J. Agric. Food Chem. | pmid:17937477 |
| Annabi B et al. | Inhibition of HuR and MMP-9 expression in macrophage-differentiated HL-60 myeloid leukemia cells by green tea polyphenol EGCg. | 2007 | Leuk. Res. | pmid:17081606 |
| Gradisar H et al. | Green tea catechins inhibit bacterial DNA gyrase by interaction with its ATP binding site. | 2007 | J. Med. Chem. | pmid:17228868 |
| You Y et al. | Identification of major phenolic compounds of Chinese water chestnut and their antioxidant activity. | 2007 | Molecules | pmid:17851436 |
| Huang CC et al. | (-)-Epicatechin-3-gallate, a green tea polyphenol is a potent agent against UVB-induced damage in HaCaT keratinocytes. | 2007 | Molecules | pmid:17960092 |
| Uekusa Y et al. | Dynamic behavior of tea catechins interacting with lipid membranes as determined by NMR spectroscopy. | 2007 | J. Agric. Food Chem. | pmid:17966973 |
| Danila AM et al. | Determination of rutin, catechin, epicatechin, and epicatechin gallate in buckwheat Fagopyrum esculentum Moench by micro-high-performance liquid chromatography with electrochemical detection. | 2007 | J. Agric. Food Chem. | pmid:17253718 |
| Kusano R et al. | Structures of epicatechin gallate trimer and tetramer produced by enzymatic oxidation. | 2007 | Chem. Pharm. Bull. | pmid:18057757 |
| Cho KN et al. | Green tea catechin (-)-epicatechin gallate induces tumour suppressor protein ATF3 via EGR-1 activation. | 2007 | Eur. J. Cancer | pmid:17764926 |
| Haginaka J et al. | Uniformly-sized, molecularly imprinted polymers for (-)-epigallocatechin gallate, -epicatechin gallate and -gallocatechin gallate by multi-step swelling and polymerization method. | 2007 | J Chromatogr A | pmid:17070533 |
| Nitta Y et al. | Food components inhibiting recombinant human histidine decarboxylase activity. | 2007 | J. Agric. Food Chem. | pmid:17227057 |
| Sannella AR et al. | Antimalarial properties of green tea. | 2007 | Biochem. Biophys. Res. Commun. | pmid:17174271 |