Epicatechin-3-gallate

Epicatechin-3-gallate is a lipid of Polyketides (PK) class. Epicatechin-3-gallate is associated with abnormalities such as Epilepsy and Megalencephaly. The involved functions are known as Docking, Drug Interactions, inhibitors, Oxidation and Inflammation Process. Epicatechin-3-gallate often locates in Solitary microtubule component of centriole or axonemal complex, Palmar surface, Glial and peritoneal. The associated genes with Epicatechin-3-gallate are Homologous Gene and TSC1 gene.

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Introduction

To understand associated biological information of Epicatechin-3-gallate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Epicatechin-3-gallate?

Epicatechin-3-gallate is suspected in Epilepsy, Megalencephaly and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Epicatechin-3-gallate

MeSH term MeSH ID Detail
Colonic Neoplasms D003110 161 associated lipids
Cicatrix D002921 9 associated lipids
Total 2

PubChem Associated disorders and diseases

What pathways are associated with Epicatechin-3-gallate

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Epicatechin-3-gallate?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Epicatechin-3-gallate?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Epicatechin-3-gallate?

There are no associated biomedical information in the current reference collection.

What genes are associated with Epicatechin-3-gallate?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Epicatechin-3-gallate?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Epicatechin-3-gallate

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Authors Title Published Journal PubMed Link
Lei S et al. Effective synthesis of theaflavin-3,3'-digallate with epigallocatechin-3-O-gallate and epicatechin gallate as substrates by using immobilized pear polyphenol oxidase. 2017 Int. J. Biol. Macromol. pmid:27780760
Zhu W et al. A-type ECG and EGCG dimers inhibit 3T3-L1 differentiation by binding to cholesterol in lipid rafts. 2017 J. Nutr. Biochem. pmid:28772148
Zinellu A et al. N- and S-homocysteinylation reduce the binding of human serum albumin to catechins. 2017 Eur J Nutr pmid:26658763
Fathima A and Rao JR Selective toxicity of Catechin-a natural flavonoid towards bacteria. 2016 Appl. Microbiol. Biotechnol. pmid:27052380
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Takechi R et al. Elevated plasma and urinary concentrations of green tea catechins associated with improved plasma lipid profile in healthy Japanese women. 2016 Nutr Res pmid:26923508
Chiou YS et al. Directly interact with Keap1 and LPS is involved in the anti-inflammatory mechanisms of (-)-epicatechin-3-gallate in LPS-induced macrophages and endotoxemia. 2016 Free Radic. Biol. Med. pmid:26878775
Godsey J and Grundmann O Review of Various Herbal Supplements as Complementary Treatments for Oral Cancer. 2016 J Diet Suppl pmid:26863913
Farhan M et al. Mobilization of Nuclear Copper by Green Tea Polyphenol Epicatechin-3-Gallate and Subsequent Prooxidant Breakage of Cellular DNA: Implications for Cancer Chemotherapy. 2016 Int J Mol Sci pmid:28035959
Kobayashi K et al. Strong Inhibition of Secretory Sphingomyelinase by Catechins, Particularly by (-)-Epicatechin 3-O-Gallate and (-)-3'-O-Methylepigallocatechin 3-O-Gallate. 2016 J. Nutr. Sci. Vitaminol. pmid:27264097
Malik S et al. Molecular mechanisms underlying attenuation of cisplatin-induced acute kidney injury by epicatechin gallate. 2016 Lab. Invest. pmid:27239733
Wein S et al. Systemic Absorption of Catechins after Intraruminal or Intraduodenal Application of a Green Tea Extract in Cows. 2016 PLoS ONE pmid:27427946
Huang SF et al. Epicatechin-3-gallate reverses TGF-β1-induced epithelial-to-mesenchymal transition and inhibits cell invasion and protease activities in human lung cancer cells. 2016 Food Chem. Toxicol. pmid:27224248
Abourashed EA et al. Content Variation of Catechin Markers, Total Phenolics and Caffeine in Green Tea Dietary Supplements. 2016 J Diet Suppl pmid:25299974
Chiu CT et al. Hibiscus sabdariffa leaf polyphenolic extract induces human melanoma cell death, apoptosis, and autophagy. 2015 J. Food Sci. pmid:25694272
Perumal S et al. Anti-infective potential of caffeic acid and epicatechin 3-gallate isolated from methanol extract of Euphorbia hirta (L.) against Pseudomonas aeruginosa. 2015 Nat. Prod. Res. pmid:25571920
Zhu YT et al. Fast identification of lipase inhibitors in oolong tea by using lipase functionalised Fe3O4 magnetic nanoparticles coupled with UPLC-MS/MS. 2015 Food Chem pmid:25466054
Song BJ et al. Thermal degradation of green tea flavan-3-ols and formation of hetero- and homocatechin dimers in model dairy beverages. 2015 Food Chem pmid:25466027
Miao M et al. Interaction mechanism between green tea extract and human α-amylase for reducing starch digestion. 2015 Food Chem pmid:25976786
Müller P and Downard KM Catechin inhibition of influenza neuraminidase and its molecular basis with mass spectrometry. 2015 J Pharm Biomed Anal pmid:25910046