| MeSH term | MeSH ID | Detail |
|---|---|---|
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Cicatrix | D002921 | 9 associated lipids |
Total
2
Epicatechin-3-gallate
Epicatechin-3-gallate is a lipid of Polyketides (PK) class. Epicatechin-3-gallate is associated with abnormalities such as Epilepsy and Megalencephaly. The involved functions are known as Docking, Drug Interactions, inhibitors, Oxidation and Inflammation Process. Epicatechin-3-gallate often locates in Solitary microtubule component of centriole or axonemal complex, Palmar surface, Glial and peritoneal. The associated genes with Epicatechin-3-gallate are Homologous Gene and TSC1 gene.
Cross Reference
Introduction
To understand associated biological information of Epicatechin-3-gallate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Epicatechin-3-gallate?
Epicatechin-3-gallate is suspected in Epilepsy, Megalencephaly and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Epicatechin-3-gallate
PubChem Associated disorders and diseases
What pathways are associated with Epicatechin-3-gallate
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Epicatechin-3-gallate?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Epicatechin-3-gallate?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Epicatechin-3-gallate?
There are no associated biomedical information in the current reference collection.
What genes are associated with Epicatechin-3-gallate?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Epicatechin-3-gallate?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Epicatechin-3-gallate
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Wan SB et al. | Study of the green tea polyphenols catechin-3-gallate (CG) and epicatechin-3-gallate (ECG) as proteasome inhibitors. | 2004 | Bioorg. Med. Chem. | pmid:15186836 |
| Anderson JC et al. | Anti-staphylococcal activity and β-lactam resistance attenuating capacity of structural analogues of (-)-epicatechin gallate. | 2011 | Bioorg. Med. Chem. Lett. | pmid:22030031 |
| Tillekeratne LM et al. | Simplified catechin-gallate inhibitors of HIV-1 reverse transcriptase. | 2001 | Bioorg. Med. Chem. Lett. | pmid:11591519 |
| Anderson JC et al. | Synthesis and antibacterial activity of hydrolytically stable (-)-epicatechin gallate analogues for the modulation of beta-lactam resistance in Staphylococcus aureus. | 2005 | Bioorg. Med. Chem. Lett. | pmid:15863332 |
| Nishimuta H et al. | Inhibitory effects of various beverages on human recombinant sulfotransferase isoforms SULT1A1 and SULT1A3. | 2007 | Biopharm Drug Dispos | pmid:17876860 |
| Hayakawa F et al. | Prooxidative activities of tea catechins in the presence of Cu2+. | 2004 | Biosci. Biotechnol. Biochem. | pmid:15388955 |
| Yamazaki T et al. | Activation of the hTAS2R14 human bitter-taste receptor by (-)-epigallocatechin gallate and (-)-epicatechin gallate. | 2013 | Biosci. Biotechnol. Biochem. | pmid:24018685 |
| Nanjo F et al. | Radical scavenging activity of tea catechins and their related compounds. | 1999 | Biosci. Biotechnol. Biochem. | pmid:10610125 |
| Satsu H et al. | Suppressive effect of nobiletin and epicatechin gallate on fructose uptake in human intestinal epithelial Caco-2 cells. | 2018 | Biosci. Biotechnol. Biochem. | pmid:29191128 |
| Sakanaka S et al. | Inhibitory effects of green tea polyphenols on growth and cellular adherence of an oral bacterium, Porphyromonas gingivalis. | 1996 | Biosci. Biotechnol. Biochem. | pmid:8704303 |
| Okushio K et al. | Methylation of tea catechins by rat liver homogenates. | 1999 | Biosci. Biotechnol. Biochem. | pmid:10192923 |
| Murakami C et al. | Effect of tea catechins on cellular lipid peroxidation and cytotoxicity in HepG2 cells. | 2002 | Biosci. Biotechnol. Biochem. | pmid:12224642 |
| Miyake T et al. | Analysis of the mechanism of inhibition of human matrix metalloproteinase 7 (MMP-7) activity by green tea catechins. | 2011 | Biosci. Biotechnol. Biochem. | pmid:21821933 |
| Ikeda I et al. | Dietary gallate esters of tea catechins reduce deposition of visceral fat, hepatic triacylglycerol, and activities of hepatic enzymes related to fatty acid synthesis in rats. | 2005 | Biosci. Biotechnol. Biochem. | pmid:15914933 |
| Schantz M et al. | Metabolism of green tea catechins by the human small intestine. | 2010 | Biotechnol J | pmid:20931601 |
| Zhang R et al. | Novel inhibitors of fatty-acid synthase from green tea (Camellia sinensis Xihu Longjing) with high activity and a new reacting site. | 2006 | Biotechnol. Appl. Biochem. | pmid:15943584 |
| Cai Y et al. | (-)-Epicatechin-3-gallate (a polyphenol from green tea) potentiates doxorubicin-induced apoptosis in H9C2 cardiomyocytes. | 2015 | Biotechnol. Lett. | pmid:26063620 |
| Kwak H et al. | Flavonoids inhibit the AU-rich element binding of HuC. | 2009 | BMB Rep | pmid:19192392 |
| Mata-Bilbao Mde L et al. | Absorption and pharmacokinetics of green tea catechins in beagles. | 2008 | Br. J. Nutr. | pmid:18205995 |
| Tsang C et al. | The absorption, metabolism and excretion of flavan-3-ols and procyanidins following the ingestion of a grape seed extract by rats. | 2005 | Br. J. Nutr. | pmid:16115350 |
| Anger DL et al. | Heteroactivation of cytochrome P450 1A1 by teas and tea polyphenols. | 2005 | Br. J. Pharmacol. | pmid:15895106 |
| Iwasaki M et al. | Plasma tea polyphenol levels and subsequent risk of breast cancer among Japanese women: a nested case-control study. | 2010 | Breast Cancer Res. Treat. | pmid:20440552 |
| Ando T et al. | Effects of tea catechins on cholesterol absorption with exogenously hypercholesterolemic rat (ExHC-Ta). | 1989 | Bull Kanagawa Dent Coll | pmid:2519221 |
| Paschka AG et al. | Induction of apoptosis in prostate cancer cell lines by the green tea component, (-)-epigallocatechin-3-gallate. | 1998 | Cancer Lett. | pmid:9751250 |
| Tan X et al. | Differences of four catechins in cell cycle arrest and induction of apoptosis in LoVo cells. | 2000 | Cancer Lett. | pmid:10940502 |
| Lamy S et al. | Green tea catechins inhibit vascular endothelial growth factor receptor phosphorylation. | 2002 | Cancer Res. | pmid:11809684 |
| Kürbitz C et al. | Epicatechin gallate and catechin gallate are superior to epigallocatechin gallate in growth suppression and anti-inflammatory activities in pancreatic tumor cells. | 2011 | Cancer Sci. | pmid:21241417 |
| Choudhary S et al. | Intervention of human breast cell carcinogenesis chronically induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine. | 2012 | Carcinogenesis | pmid:22307971 |
| Baek SJ et al. | Epicatechin gallate-induced expression of NAG-1 is associated with growth inhibition and apoptosis in colon cancer cells. | 2004 | Carcinogenesis | pmid:15308587 |
| Rathore K et al. | Green tea catechin intervention of reactive oxygen species-mediated ERK pathway activation and chronically induced breast cell carcinogenesis. | 2012 | Carcinogenesis | pmid:22045026 |
| El Bedoui J et al. | Catechins prevent vascular smooth muscle cell invasion by inhibiting MT1-MMP activity and MMP-2 expression. | 2005 | Cardiovasc. Res. | pmid:15885676 |
| Isemura M et al. | Effects of catechins on the mouse lung carcinoma cell adhesion to the endothelial cells. | 1993 | Cell Biol. Int. | pmid:8348114 |
| Hosokawa Y et al. | Catechins inhibit CCL20 production in IL-17A-stimulated human gingival fibroblasts. | 2009 | Cell. Physiol. Biochem. | pmid:19910679 |
| Vyas S et al. | Potential O-acyl-substituted (-)-Epicatechin gallate prodrugs as inhibitors of DMBA/TPA-induced squamous cell carcinoma of skin in Swiss albino mice. | 2011 | Chem. Biodivers. | pmid:21480506 |
| Kaneko T et al. | Inhibition of linoleic acid hydroperoxide-induced toxicity in cultured human umbilical vein endothelial cells by catechins. | 1998 | Chem. Biol. Interact. | pmid:9744559 |
| Kennedy DO et al. | Involvement of protein tyrosine phosphorylation in the effect of green tea polyphenols on Ehrlich ascites tumor cells in vitro. | 1998 | Chem. Biol. Interact. | pmid:9609384 |
| Tsuchiya H | Stereospecificity in membrane effects of catechins. | 2001 | Chem. Biol. Interact. | pmid:11248221 |
| Stadlbauer S et al. | A new synthetic strategy for catechin-class polyphenols: concise synthesis of (-)-epicatechin and its 3-O-gallate. | 2012 | Chem. Commun. (Camb.) | pmid:22790234 |
| Sato T et al. | Characterization of creaming precipitate of tea catechins and caffeine in aqueous solution. | 2012 | Chem. Pharm. Bull. | pmid:22976328 |
| Fan W et al. | Prolyl endopeptidase inhibitory activity of fourteen Kampo formulas and inhibitory constituents of Tokaku-joki-to. | 2000 | Chem. Pharm. Bull. | pmid:10923840 |
| Kusano R et al. | Structures of epicatechin gallate trimer and tetramer produced by enzymatic oxidation. | 2007 | Chem. Pharm. Bull. | pmid:18057757 |
| Agusta A et al. | Stereoselective oxidation at C-4 of flavans by the endophytic fungus Diaporthe sp. isolated from a tea plant. | 2005 | Chem. Pharm. Bull. | pmid:16327190 |
| Liu Z et al. | Antioxidative effects of green tea polyphenols on free radical initiated and photosensitized peroxidation of human low density lipoprotein. | 2000 | Chem. Phys. Lipids | pmid:10878235 |
| Chen L et al. | Tea catechins protect against lead-induced ROS formation, mitochondrial dysfunction, and calcium dysregulation in PC12 cells. | 2003 | Chem. Res. Toxicol. | pmid:12971804 |
| Kawai Y et al. | Galloylated catechins as potent inhibitors of hypochlorous acid-induced DNA damage. | 2008 | Chem. Res. Toxicol. | pmid:18512968 |
| Chen L et al. | Effect of tea catechins on the change of glutathione levels caused by Pb(++) in PC12 cells. | 2004 | Chem. Res. Toxicol. | pmid:15257617 |
| Ishii T et al. | Catechol type polyphenol is a potential modifier of protein sulfhydryls: development and application of a new probe for understanding the dietary polyphenol actions. | 2009 | Chem. Res. Toxicol. | pmid:19743802 |
| Cao P et al. | Effect of green tea catechins and hydrolyzable tannins on benzo[a]pyrene-induced DNA adducts and structure-activity relationship. | 2010 | Chem. Res. Toxicol. | pmid:20218540 |
| Pandey KB et al. | Erythrocyte membrane transporters during human ageing: modulatory role of tea catechins. | 2013 | Clin. Exp. Pharmacol. Physiol. | pmid:23240554 |
| Jiang F et al. | The evaluation of catechins that contain a galloyl moiety as potential HIV-1 integrase inhibitors. | 2010 | Clin. Immunol. | pmid:20832370 |