Epicatechin-3-gallate

Epicatechin-3-gallate is a lipid of Polyketides (PK) class. Epicatechin-3-gallate is associated with abnormalities such as Epilepsy and Megalencephaly. The involved functions are known as Docking, Drug Interactions, inhibitors, Oxidation and Inflammation Process. Epicatechin-3-gallate often locates in Solitary microtubule component of centriole or axonemal complex, Palmar surface, Glial and peritoneal. The associated genes with Epicatechin-3-gallate are Homologous Gene and TSC1 gene.

Cross Reference

Introduction

To understand associated biological information of Epicatechin-3-gallate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Epicatechin-3-gallate?

Epicatechin-3-gallate is suspected in Epilepsy, Megalencephaly and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Epicatechin-3-gallate

MeSH term MeSH ID Detail
Colonic Neoplasms D003110 161 associated lipids
Cicatrix D002921 9 associated lipids
Total 2

PubChem Associated disorders and diseases

What pathways are associated with Epicatechin-3-gallate

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Epicatechin-3-gallate?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Epicatechin-3-gallate?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Epicatechin-3-gallate?

There are no associated biomedical information in the current reference collection.

What genes are associated with Epicatechin-3-gallate?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Epicatechin-3-gallate?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Epicatechin-3-gallate

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Authors Title Published Journal PubMed Link
Zinellu A et al. N- and S-homocysteinylation reduce the binding of human serum albumin to catechins. 2017 Eur J Nutr pmid:26658763
Godsey J and Grundmann O Review of Various Herbal Supplements as Complementary Treatments for Oral Cancer. 2016 J Diet Suppl pmid:26863913
Chiou YS et al. Directly interact with Keap1 and LPS is involved in the anti-inflammatory mechanisms of (-)-epicatechin-3-gallate in LPS-induced macrophages and endotoxemia. 2016 Free Radic. Biol. Med. pmid:26878775
Takechi R et al. Elevated plasma and urinary concentrations of green tea catechins associated with improved plasma lipid profile in healthy Japanese women. 2016 Nutr Res pmid:26923508
Fathima A and Rao JR Selective toxicity of Catechin-a natural flavonoid towards bacteria. 2016 Appl. Microbiol. Biotechnol. pmid:27052380
Huang SF et al. Epicatechin-3-gallate reverses TGF-β1-induced epithelial-to-mesenchymal transition and inhibits cell invasion and protease activities in human lung cancer cells. 2016 Food Chem. Toxicol. pmid:27224248
Malik S et al. Molecular mechanisms underlying attenuation of cisplatin-induced acute kidney injury by epicatechin gallate. 2016 Lab. Invest. pmid:27239733
Kobayashi K et al. Strong Inhibition of Secretory Sphingomyelinase by Catechins, Particularly by (-)-Epicatechin 3-O-Gallate and (-)-3'-O-Methylepigallocatechin 3-O-Gallate. 2016 J. Nutr. Sci. Vitaminol. pmid:27264097
Chen JH et al. Autophagic effects of Hibiscus sabdariffa leaf polyphenols and epicatechin gallate (ECG) against oxidized LDL-induced injury of human endothelial cells. 2017 Eur J Nutr pmid:27318926
Wein S et al. Systemic Absorption of Catechins after Intraruminal or Intraduodenal Application of a Green Tea Extract in Cows. 2016 PLoS ONE pmid:27427946