Epicatechin-3-gallate

Epicatechin-3-gallate is a lipid of Polyketides (PK) class. Epicatechin-3-gallate is associated with abnormalities such as Epilepsy and Megalencephaly. The involved functions are known as Docking, Drug Interactions, inhibitors, Oxidation and Inflammation Process. Epicatechin-3-gallate often locates in Solitary microtubule component of centriole or axonemal complex, Palmar surface, Glial and peritoneal. The associated genes with Epicatechin-3-gallate are Homologous Gene and TSC1 gene.

Cross Reference

Introduction

To understand associated biological information of Epicatechin-3-gallate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Epicatechin-3-gallate?

Epicatechin-3-gallate is suspected in Epilepsy, Megalencephaly and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Epicatechin-3-gallate

MeSH term MeSH ID Detail
Colonic Neoplasms D003110 161 associated lipids
Cicatrix D002921 9 associated lipids
Total 2

PubChem Associated disorders and diseases

What pathways are associated with Epicatechin-3-gallate

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Epicatechin-3-gallate?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Epicatechin-3-gallate?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Epicatechin-3-gallate?

There are no associated biomedical information in the current reference collection.

What genes are associated with Epicatechin-3-gallate?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Epicatechin-3-gallate?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Epicatechin-3-gallate

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Authors Title Published Journal PubMed Link
Chen D et al. Inhibition of human liver catechol-O-methyltransferase by tea catechins and their metabolites: structure-activity relationship and molecular-modeling studies. 2005 Biochem. Pharmacol. pmid:15857617
Wu AZ et al. Antiarrhythmic effects of (-)-epicatechin-3-gallate, a novel sodium channel agonist in cultured neonatal rat ventricular myocytes. 2013 Biochem. Pharmacol. pmid:23116965
Wang X et al. The galloyl moiety of green tea catechins is the critical structural feature to inhibit fatty-acid synthase. 2003 Biochem. Pharmacol. pmid:14599562
Feng W et al. Green tea catechins are potent sensitizers of ryanodine receptor type 1 (RyR1). 2010 Biochem. Pharmacol. pmid:20471964
Kamihira-Ishijima M et al. Inhibitory mechanism of pancreatic amyloid fibril formation: formation of the complex between tea catechins and the fragment of residues 22-27. 2012 Biochemistry pmid:23205879
Navarro-Perán E et al. Kinetics of the inhibition of bovine liver dihydrofolate reductase by tea catechins: origin of slow-binding inhibition and pH studies. 2005 Biochemistry pmid:15895994
Ikeda I et al. Tea catechins decrease micellar solubility and intestinal absorption of cholesterol in rats. 1992 Biochim. Biophys. Acta pmid:1643098
Trnková L et al. Green tea catechins can bind and modify ERp57/PDIA3 activity. 2013 Biochim. Biophys. Acta pmid:23671928
Mochizuki M et al. Kinetic analysis and mechanistic aspects of autoxidation of catechins. 2002 Biochim. Biophys. Acta pmid:11853955
Uekusa Y et al. Interaction of epicatechin gallate with phospholipid membranes as revealed by solid-state NMR spectroscopy. 2011 Biochim. Biophys. Acta pmid:21352801