Epicatechin-3-gallate

Epicatechin-3-gallate is a lipid of Polyketides (PK) class. Epicatechin-3-gallate is associated with abnormalities such as Epilepsy and Megalencephaly. The involved functions are known as Docking, Drug Interactions, inhibitors, Oxidation and Inflammation Process. Epicatechin-3-gallate often locates in Solitary microtubule component of centriole or axonemal complex, Palmar surface, Glial and peritoneal. The associated genes with Epicatechin-3-gallate are Homologous Gene and TSC1 gene.

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Introduction

To understand associated biological information of Epicatechin-3-gallate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Epicatechin-3-gallate?

Epicatechin-3-gallate is suspected in Epilepsy, Megalencephaly and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Epicatechin-3-gallate

MeSH term MeSH ID Detail
Colonic Neoplasms D003110 161 associated lipids
Cicatrix D002921 9 associated lipids
Total 2

PubChem Associated disorders and diseases

What pathways are associated with Epicatechin-3-gallate

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Epicatechin-3-gallate?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Epicatechin-3-gallate?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Epicatechin-3-gallate?

There are no associated biomedical information in the current reference collection.

What genes are associated with Epicatechin-3-gallate?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Epicatechin-3-gallate?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Epicatechin-3-gallate

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Authors Title Published Journal PubMed Link
Mukai K et al. Structure-activity relationship of the tocopherol-regeneration reaction by catechins. 2005 Free Radic. Biol. Med. pmid:15808422
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Kumar NS and Rajapaksha M Separation of catechin constituents from five tea cultivars using high-speed counter-current chromatography. 2005 J Chromatogr A pmid:16078712
Mukai K et al. Kinetic study of the quenching reaction of singlet oxygen by tea catechins in ethanol solution. 2005 Free Radic. Biol. Med. pmid:16109305
Babich H et al. Differential in vitro cytotoxicity of (-)-epicatechin gallate (ECG) to cancer and normal cells from the human oral cavity. 2005 Toxicol In Vitro pmid:15649637
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Huang CC et al. Protective effects of (-)-epicatechin-3-gallate on UVA-induced damage in HaCaT keratinocytes. 2005 Arch. Dermatol. Res. pmid:15726391
Navarro-Perán E et al. Kinetics of the inhibition of bovine liver dihydrofolate reductase by tea catechins: origin of slow-binding inhibition and pH studies. 2005 Biochemistry pmid:15895994
El Bedoui J et al. Catechins prevent vascular smooth muscle cell invasion by inhibiting MT1-MMP activity and MMP-2 expression. 2005 Cardiovasc. Res. pmid:15885676
Song JM et al. Antiviral effect of catechins in green tea on influenza virus. 2005 Antiviral Res. pmid:16137775
Stapleton PD et al. Potentiation of catechin gallate-mediated sensitization of Staphylococcus aureus to oxacillin by nongalloylated catechins. 2006 Antimicrob. Agents Chemother. pmid:16436737
Luximon-Ramma A et al. Assessment of the polyphenolic composition of the organic extracts of Mauritian black teas: a potential contributor to their antioxidant functions. 2006 Biofactors pmid:17012766
Daniel KG et al. Methylation of green tea polyphenols affects their binding to and inhibitory poses of the proteasome beta5 subunit. 2006 Int. J. Mol. Med. pmid:16964415
Wang R et al. Kinetic study of the thermal stability of tea catechins in aqueous systems using a microwave reactor. 2006 J. Agric. Food Chem. pmid:16881696
Stapleton PD et al. Epicatechin gallate, a component of green tea, reduces halotolerance in Staphylococcus aureus. 2006 Int. J. Food Microbiol. pmid:16839636
Hayes CJ et al. Synthesis and preliminary anticancer activity studies of C4 and C8-modified derivatives of catechin gallate (CG) and epicatechin gallate (ECG). 2006 J. Org. Chem. pmid:17168588
Si W et al. Bioassay-guided purification and identification of antimicrobial components in Chinese green tea extract. 2006 J Chromatogr A pmid:16797571