Epicatechin-3-gallate

Epicatechin-3-gallate is a lipid of Polyketides (PK) class. Epicatechin-3-gallate is associated with abnormalities such as Epilepsy and Megalencephaly. The involved functions are known as Docking, Drug Interactions, inhibitors, Oxidation and Inflammation Process. Epicatechin-3-gallate often locates in Solitary microtubule component of centriole or axonemal complex, Palmar surface, Glial and peritoneal. The associated genes with Epicatechin-3-gallate are Homologous Gene and TSC1 gene.

Cross Reference

Introduction

To understand associated biological information of Epicatechin-3-gallate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Epicatechin-3-gallate?

Epicatechin-3-gallate is suspected in Epilepsy, Megalencephaly and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Epicatechin-3-gallate

MeSH term MeSH ID Detail
Colonic Neoplasms D003110 161 associated lipids
Cicatrix D002921 9 associated lipids
Total 2

PubChem Associated disorders and diseases

What pathways are associated with Epicatechin-3-gallate

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Epicatechin-3-gallate?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Epicatechin-3-gallate?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Epicatechin-3-gallate?

There are no associated biomedical information in the current reference collection.

What genes are associated with Epicatechin-3-gallate?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Epicatechin-3-gallate?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Epicatechin-3-gallate

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Authors Title Published Journal PubMed Link
Anger DL et al. Heteroactivation of cytochrome P450 1A1 by teas and tea polyphenols. 2005 Br. J. Pharmacol. pmid:15895106
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Ando T et al. Effects of tea catechins on cholesterol absorption with exogenously hypercholesterolemic rat (ExHC-Ta). 1989 Bull Kanagawa Dent Coll pmid:2519221
Paschka AG et al. Induction of apoptosis in prostate cancer cell lines by the green tea component, (-)-epigallocatechin-3-gallate. 1998 Cancer Lett. pmid:9751250
Tan X et al. Differences of four catechins in cell cycle arrest and induction of apoptosis in LoVo cells. 2000 Cancer Lett. pmid:10940502
Lamy S et al. Green tea catechins inhibit vascular endothelial growth factor receptor phosphorylation. 2002 Cancer Res. pmid:11809684
Kürbitz C et al. Epicatechin gallate and catechin gallate are superior to epigallocatechin gallate in growth suppression and anti-inflammatory activities in pancreatic tumor cells. 2011 Cancer Sci. pmid:21241417
Choudhary S et al. Intervention of human breast cell carcinogenesis chronically induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine. 2012 Carcinogenesis pmid:22307971
Baek SJ et al. Epicatechin gallate-induced expression of NAG-1 is associated with growth inhibition and apoptosis in colon cancer cells. 2004 Carcinogenesis pmid:15308587
Rathore K et al. Green tea catechin intervention of reactive oxygen species-mediated ERK pathway activation and chronically induced breast cell carcinogenesis. 2012 Carcinogenesis pmid:22045026